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Evaluation of sodium stibogluconate in the treatment of cutaneous leishmaniasis in Syria.
Curr Med Res Opin. 1979; 6(4):280-3.CM

Abstract

A series of 31 patients presenting with skin lesions with positive smears for leishmania parasites were treated with sodium stibogluconate (each ml of injection containing the equivalent of 100 mg pentavalent antimony). The drug was administered either intramuscularly at a dosage of 6 ml daily for at least 10 days or infiltrated around the lesion (maximum 2 ml per lesion) at weekly intervals for 3 to 4 consecutive weeks. Twenty-four (77%) of the patients were assessed as showing a successful response, with parasites absent from the smear and the lesions healing at the end of treatment. Poor results, however, were reported in 5 of the 16 patients treated solely by infiltration. Follow-up of a few patients at 3 months showed that the healing process was prompt and little disfiguration was produced, lesions on the trunk tending to heal more quickly than those on the face.

Authors

No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

230939

Citation

Ghosn, S. "Evaluation of Sodium Stibogluconate in the Treatment of Cutaneous Leishmaniasis in Syria." Current Medical Research and Opinion, vol. 6, no. 4, 1979, pp. 280-3.
Ghosn S. Evaluation of sodium stibogluconate in the treatment of cutaneous leishmaniasis in Syria. Curr Med Res Opin. 1979;6(4):280-3.
Ghosn, S. (1979). Evaluation of sodium stibogluconate in the treatment of cutaneous leishmaniasis in Syria. Current Medical Research and Opinion, 6(4), 280-3.
Ghosn S. Evaluation of Sodium Stibogluconate in the Treatment of Cutaneous Leishmaniasis in Syria. Curr Med Res Opin. 1979;6(4):280-3. PubMed PMID: 230939.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of sodium stibogluconate in the treatment of cutaneous leishmaniasis in Syria. A1 - Ghosn,S, PY - 1979/1/1/pubmed PY - 1979/1/1/medline PY - 1979/1/1/entrez SP - 280 EP - 3 JF - Current medical research and opinion JO - Curr Med Res Opin VL - 6 IS - 4 N2 - A series of 31 patients presenting with skin lesions with positive smears for leishmania parasites were treated with sodium stibogluconate (each ml of injection containing the equivalent of 100 mg pentavalent antimony). The drug was administered either intramuscularly at a dosage of 6 ml daily for at least 10 days or infiltrated around the lesion (maximum 2 ml per lesion) at weekly intervals for 3 to 4 consecutive weeks. Twenty-four (77%) of the patients were assessed as showing a successful response, with parasites absent from the smear and the lesions healing at the end of treatment. Poor results, however, were reported in 5 of the 16 patients treated solely by infiltration. Follow-up of a few patients at 3 months showed that the healing process was prompt and little disfiguration was produced, lesions on the trunk tending to heal more quickly than those on the face. SN - 0300-7995 UR - https://www.unboundmedicine.com/medline/citation/230939/Evaluation_of_sodium_stibogluconate_in_the_treatment_of_cutaneous_leishmaniasis_in_Syria_ L2 - https://www.tandfonline.com/doi/full/10.1185/03007997909109438 DB - PRIME DP - Unbound Medicine ER -