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Alteration of vitamin D metabolism in Mexican-Americans.
J Bone Miner Res 1990; 5(1):13-7JB

Abstract

Studies were performed to investigate vitamin D metabolism in Mexican-Americans. Groups of 15 whites and 16 Mexican-Americans ranging in age from 18 to 41 years were evaluated. All of them were within 25% of their ideal body weight. Each of them was admitted to the Clinical Research Center of the University of Texas Health Science Center and placed on a daily diet estimated to contain 400 mg calcium and 900 mg phosphate. It was found that whereas serum vitamin D (1.8 +/- 0.5 versus 7.6 +/- 1.3 ng/ml, P less than 0.001) and serum 25-hydroxyvitamin D (9 +/- 1 versus 17 +/- 2 ng/ml, P less than 0.01) were significantly lower and serum 1,25-dihydroxyvitamin D (37 +/- 2 versus 28 +/- 2 pg/ml, P less than 0.001) was significantly higher in the Mexican-Americans than in the whites, serum calcium (9.1 +/- 0.1 versus 9.2 +/- 0.1 mg/dl), magnesium (1.84 +/- 0.07 versus 1.80 +/- 0.07 mEq/liter), and Gla protein (19 +/- 3 versus 21 +/- 2 ng/ml) were not different in the two groups. Urinary calcium (144 +/- 14 versus 124 +/- 16 mg/day), phosphate (672 +/- 51 versus 683 +/- 44 mg/day), sodium (110 +/- 8 versus 99 +/- 9 mEq/day), potassium (43 +/- 4 versus 49 +/- 3 mEq/day), and magnesium (7.3 +/- 0.7 versus 7.7 +/- 0.5 mEq/day) and creatinine clearance (173 +/- 14 versus 154 +/- 7 liters/day) were not different in the two groups.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

Department of Medicine, University of Texas Health Science Center, San Antonio.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

2309575

Citation

Reasner, C A., et al. "Alteration of Vitamin D Metabolism in Mexican-Americans." Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, vol. 5, no. 1, 1990, pp. 13-7.
Reasner CA, Dunn JF, Fetchick DA, et al. Alteration of vitamin D metabolism in Mexican-Americans. J Bone Miner Res. 1990;5(1):13-7.
Reasner, C. A., Dunn, J. F., Fetchick, D. A., Liel, Y., Hollis, B. W., Epstein, S., ... Bell, N. H. (1990). Alteration of vitamin D metabolism in Mexican-Americans. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 5(1), pp. 13-7.
Reasner CA, et al. Alteration of Vitamin D Metabolism in Mexican-Americans. J Bone Miner Res. 1990;5(1):13-7. PubMed PMID: 2309575.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alteration of vitamin D metabolism in Mexican-Americans. AU - Reasner,C A,2nd AU - Dunn,J F, AU - Fetchick,D A, AU - Liel,Y, AU - Hollis,B W, AU - Epstein,S, AU - Shary,J, AU - Mundy,G R, AU - Bell,N H, PY - 1990/1/1/pubmed PY - 1990/1/1/medline PY - 1990/1/1/entrez SP - 13 EP - 7 JF - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research JO - J. Bone Miner. Res. VL - 5 IS - 1 N2 - Studies were performed to investigate vitamin D metabolism in Mexican-Americans. Groups of 15 whites and 16 Mexican-Americans ranging in age from 18 to 41 years were evaluated. All of them were within 25% of their ideal body weight. Each of them was admitted to the Clinical Research Center of the University of Texas Health Science Center and placed on a daily diet estimated to contain 400 mg calcium and 900 mg phosphate. It was found that whereas serum vitamin D (1.8 +/- 0.5 versus 7.6 +/- 1.3 ng/ml, P less than 0.001) and serum 25-hydroxyvitamin D (9 +/- 1 versus 17 +/- 2 ng/ml, P less than 0.01) were significantly lower and serum 1,25-dihydroxyvitamin D (37 +/- 2 versus 28 +/- 2 pg/ml, P less than 0.001) was significantly higher in the Mexican-Americans than in the whites, serum calcium (9.1 +/- 0.1 versus 9.2 +/- 0.1 mg/dl), magnesium (1.84 +/- 0.07 versus 1.80 +/- 0.07 mEq/liter), and Gla protein (19 +/- 3 versus 21 +/- 2 ng/ml) were not different in the two groups. Urinary calcium (144 +/- 14 versus 124 +/- 16 mg/day), phosphate (672 +/- 51 versus 683 +/- 44 mg/day), sodium (110 +/- 8 versus 99 +/- 9 mEq/day), potassium (43 +/- 4 versus 49 +/- 3 mEq/day), and magnesium (7.3 +/- 0.7 versus 7.7 +/- 0.5 mEq/day) and creatinine clearance (173 +/- 14 versus 154 +/- 7 liters/day) were not different in the two groups.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0884-0431 UR - https://www.unboundmedicine.com/medline/citation/2309575/Alteration_of_vitamin_D_metabolism_in_Mexican_Americans_ L2 - https://doi.org/10.1002/jbmr.5650050105 DB - PRIME DP - Unbound Medicine ER -