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Fecal microbiota transplantation: techniques, applications, and issues.
Gastroenterol Clin North Am 2012; 41(4):781-803GC

Abstract

Fecal microbiota transplantation (FMT) has gained widespread recognition in light of the recent Clostridium difficile infection (CDI) epidemic, responsible for almost 110,000 deaths per year. The procedure's success rate has caused experts to reflect on what other conditions may benefit. This article provides an overview of (1) description and history of FMT, (2) FMT publications in CDI, (3) the concept of the gut microbiota as a virtual organ, (4) rationale for FMT use, (5) FMT use in inflammatory bowel disease, (6) emerging FMT applications, (7) how FMT is currently performed, and (8) how FMT may be performed in the future.

Authors+Show Affiliations

Centre for Digestive Diseases, Level 1, 229 Great North Road, Five Dock, New South Wales 2046, Australia.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23101687

Citation

Borody, Thomas Julius, and Jordana Campbell. "Fecal Microbiota Transplantation: Techniques, Applications, and Issues." Gastroenterology Clinics of North America, vol. 41, no. 4, 2012, pp. 781-803.
Borody TJ, Campbell J. Fecal microbiota transplantation: techniques, applications, and issues. Gastroenterol Clin North Am. 2012;41(4):781-803.
Borody, T. J., & Campbell, J. (2012). Fecal microbiota transplantation: techniques, applications, and issues. Gastroenterology Clinics of North America, 41(4), pp. 781-803. doi:10.1016/j.gtc.2012.08.008.
Borody TJ, Campbell J. Fecal Microbiota Transplantation: Techniques, Applications, and Issues. Gastroenterol Clin North Am. 2012;41(4):781-803. PubMed PMID: 23101687.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fecal microbiota transplantation: techniques, applications, and issues. AU - Borody,Thomas Julius, AU - Campbell,Jordana, PY - 2012/10/30/entrez PY - 2012/10/30/pubmed PY - 2013/4/30/medline SP - 781 EP - 803 JF - Gastroenterology clinics of North America JO - Gastroenterol. Clin. North Am. VL - 41 IS - 4 N2 - Fecal microbiota transplantation (FMT) has gained widespread recognition in light of the recent Clostridium difficile infection (CDI) epidemic, responsible for almost 110,000 deaths per year. The procedure's success rate has caused experts to reflect on what other conditions may benefit. This article provides an overview of (1) description and history of FMT, (2) FMT publications in CDI, (3) the concept of the gut microbiota as a virtual organ, (4) rationale for FMT use, (5) FMT use in inflammatory bowel disease, (6) emerging FMT applications, (7) how FMT is currently performed, and (8) how FMT may be performed in the future. SN - 1558-1942 UR - https://www.unboundmedicine.com/medline/citation/23101687/Fecal_microbiota_transplantation:_techniques_applications_and_issues_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0889-8553(12)00102-1 DB - PRIME DP - Unbound Medicine ER -