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Diagnosis and management of alcoholic hepatitis.
Clin Liver Dis 2012; 16(4):717-36CL

Abstract

Alcoholic hepatitis is a form of severe, cholestatic liver disease that results from consumption of large amount of alcohol during a sustained period of time in a subset of alcoholics. Symptoms could be mild and nonspecific to more severe. The diagnosis of alcoholic hepatitis can be made with a thorough history, physical examination, and review of laboratory results. Liver biopsy is confirmatory but generally not indicated for the diagnosis. Abstinence is the key form of therapeutic intervention. Despite variable results in clinical trials, corticosteroids and pentoxifylline seem to provide moderate survival benefit. Liver transplantation in acute alcoholic hepatitis is contentious.

Authors+Show Affiliations

University of Tennessee Health sciences center,1211 Union Avenue, Memphis, TN 38104, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23101979

Citation

Sohail, Umair, and Sanjaya K. Satapathy. "Diagnosis and Management of Alcoholic Hepatitis." Clinics in Liver Disease, vol. 16, no. 4, 2012, pp. 717-36.
Sohail U, Satapathy SK. Diagnosis and management of alcoholic hepatitis. Clin Liver Dis. 2012;16(4):717-36.
Sohail, U., & Satapathy, S. K. (2012). Diagnosis and management of alcoholic hepatitis. Clinics in Liver Disease, 16(4), pp. 717-36. doi:10.1016/j.cld.2012.08.005.
Sohail U, Satapathy SK. Diagnosis and Management of Alcoholic Hepatitis. Clin Liver Dis. 2012;16(4):717-36. PubMed PMID: 23101979.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis and management of alcoholic hepatitis. AU - Sohail,Umair, AU - Satapathy,Sanjaya K, PY - 2012/10/30/entrez PY - 2012/10/30/pubmed PY - 2013/4/13/medline SP - 717 EP - 36 JF - Clinics in liver disease JO - Clin Liver Dis VL - 16 IS - 4 N2 - Alcoholic hepatitis is a form of severe, cholestatic liver disease that results from consumption of large amount of alcohol during a sustained period of time in a subset of alcoholics. Symptoms could be mild and nonspecific to more severe. The diagnosis of alcoholic hepatitis can be made with a thorough history, physical examination, and review of laboratory results. Liver biopsy is confirmatory but generally not indicated for the diagnosis. Abstinence is the key form of therapeutic intervention. Despite variable results in clinical trials, corticosteroids and pentoxifylline seem to provide moderate survival benefit. Liver transplantation in acute alcoholic hepatitis is contentious. SN - 1557-8224 UR - https://www.unboundmedicine.com/medline/citation/23101979/Diagnosis_and_management_of_alcoholic_hepatitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1089-3261(12)00088-8 DB - PRIME DP - Unbound Medicine ER -