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Being overweight or obese is associated with decreased mortality in critically ill patients: a retrospective analysis of a large regional Italian multicenter cohort.
J Crit Care. 2012 Dec; 27(6):714-21.JC

Abstract

PURPOSE

To describe the epidemiology of obesity in a large cohort of intensive care unit (ICU) patients and study its impact on outcomes.

METHODS

All 3902 patients admitted to one of 24 ICUs in the Piedmont region of Italy from April 3 to September 29, 2006, were included in this retrospective analysis of data from a prospective, multicenter study.

RESULTS

Mean body mass index (BMI) was 26.0 ± 5.4 kg/m(2): 32.8% of patients had a normal BMI, 2.6% were underweight, 45.1% overweight, 16.5% obese, and 2.9% morbidly obese. ICU mortality was significantly (P < .05) lower in overweight (18.8%) and obese (17.5%) patients than in those of normal BMI (22%). In multivariate logistic regression analysis, being overweight (OR = 0.73; 95%CI: 0.58-0.91, P = .007) or obese (OR = 0.62; 95%CI: 50.45-0.85, P = .003) was associated with a reduced risk of ICU death. Being morbidly obese was independently associated with an increased risk of death in elective surgery patients whereas being underweight was independently associated with an increased risk of death in patients admitted for short-term monitoring and after elective surgery.

CONCLUSIONS

In this cohort, overweight and obese patients had a reduced risk of ICU death. Being underweight or morbidly obese was associated with an increased risk of death in some subgroups of patients.

Authors+Show Affiliations

Department of Anesthesiology and Intensive Care, Friedrich-Schiller-University, Erlanger Allee 103, 07743 Jena, Germany. yasser.sakr@med.uni-jena.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23102526

Citation

Sakr, Yasser, et al. "Being Overweight or Obese Is Associated With Decreased Mortality in Critically Ill Patients: a Retrospective Analysis of a Large Regional Italian Multicenter Cohort." Journal of Critical Care, vol. 27, no. 6, 2012, pp. 714-21.
Sakr Y, Elia C, Mascia L, et al. Being overweight or obese is associated with decreased mortality in critically ill patients: a retrospective analysis of a large regional Italian multicenter cohort. J Crit Care. 2012;27(6):714-21.
Sakr, Y., Elia, C., Mascia, L., Barberis, B., Cardellino, S., Livigni, S., Fiore, G., Filippini, C., & Ranieri, V. M. (2012). Being overweight or obese is associated with decreased mortality in critically ill patients: a retrospective analysis of a large regional Italian multicenter cohort. Journal of Critical Care, 27(6), 714-21. https://doi.org/10.1016/j.jcrc.2012.08.013
Sakr Y, et al. Being Overweight or Obese Is Associated With Decreased Mortality in Critically Ill Patients: a Retrospective Analysis of a Large Regional Italian Multicenter Cohort. J Crit Care. 2012;27(6):714-21. PubMed PMID: 23102526.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Being overweight or obese is associated with decreased mortality in critically ill patients: a retrospective analysis of a large regional Italian multicenter cohort. AU - Sakr,Yasser, AU - Elia,Cristina, AU - Mascia,Luciana, AU - Barberis,Bruno, AU - Cardellino,Silvano, AU - Livigni,Sergio, AU - Fiore,Gilberto, AU - Filippini,Claudia, AU - Ranieri,V Marco, Y1 - 2012/10/24/ PY - 2012/01/25/received PY - 2012/08/08/revised PY - 2012/08/19/accepted PY - 2012/10/30/entrez PY - 2012/10/30/pubmed PY - 2013/5/31/medline SP - 714 EP - 21 JF - Journal of critical care JO - J Crit Care VL - 27 IS - 6 N2 - PURPOSE: To describe the epidemiology of obesity in a large cohort of intensive care unit (ICU) patients and study its impact on outcomes. METHODS: All 3902 patients admitted to one of 24 ICUs in the Piedmont region of Italy from April 3 to September 29, 2006, were included in this retrospective analysis of data from a prospective, multicenter study. RESULTS: Mean body mass index (BMI) was 26.0 ± 5.4 kg/m(2): 32.8% of patients had a normal BMI, 2.6% were underweight, 45.1% overweight, 16.5% obese, and 2.9% morbidly obese. ICU mortality was significantly (P < .05) lower in overweight (18.8%) and obese (17.5%) patients than in those of normal BMI (22%). In multivariate logistic regression analysis, being overweight (OR = 0.73; 95%CI: 0.58-0.91, P = .007) or obese (OR = 0.62; 95%CI: 50.45-0.85, P = .003) was associated with a reduced risk of ICU death. Being morbidly obese was independently associated with an increased risk of death in elective surgery patients whereas being underweight was independently associated with an increased risk of death in patients admitted for short-term monitoring and after elective surgery. CONCLUSIONS: In this cohort, overweight and obese patients had a reduced risk of ICU death. Being underweight or morbidly obese was associated with an increased risk of death in some subgroups of patients. SN - 1557-8615 UR - https://www.unboundmedicine.com/medline/citation/23102526/Being_overweight_or_obese_is_associated_with_decreased_mortality_in_critically_ill_patients:_a_retrospective_analysis_of_a_large_regional_Italian_multicenter_cohort_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0883-9441(12)00297-3 DB - PRIME DP - Unbound Medicine ER -