Tags

Type your tag names separated by a space and hit enter

Synthesis of pyrazolo[5,1-a]isoquinolines via silver(I)-rhodium(I) cooperative catalysis in the reaction of N'-(2-alkynylbenzylidene)hydrazide with cycloprop-2-ene-1,1-dicarboxylate.
Org Biomol Chem. 2012 Dec 21; 10(47):9447-51.OB

Abstract

A tandem reaction between N'-(2-alkynylbenzylidene)hydrazide and cycloprop-2-ene-1,1-dicarboxylate co-catalyzed by silver triflate and tris(triphenylphosphine)rhodium chloride is reported. The reaction proceeds through 6-endo-cyclization, [3 + 2] cycloaddition, cyclopropane opening, and aromatization, leading to pyrazolo[5,1-a]isoquinolines in moderate to good yields.

Authors+Show Affiliations

Obstetrics and Gynecology Hospital, Fudan University, 419 Fangxie Road, Shanghai 200011, China. yaoliangqingcn@126.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23117441

Citation

Yao, Liangqing, et al. "Synthesis of Pyrazolo[5,1-a]isoquinolines Via silver(I)-rhodium(I) Cooperative Catalysis in the Reaction of N'-(2-alkynylbenzylidene)hydrazide With Cycloprop-2-ene-1,1-dicarboxylate." Organic & Biomolecular Chemistry, vol. 10, no. 47, 2012, pp. 9447-51.
Yao L, Yu X, Mo C, et al. Synthesis of pyrazolo[5,1-a]isoquinolines via silver(I)-rhodium(I) cooperative catalysis in the reaction of N'-(2-alkynylbenzylidene)hydrazide with cycloprop-2-ene-1,1-dicarboxylate. Org Biomol Chem. 2012;10(47):9447-51.
Yao, L., Yu, X., Mo, C., & Wu, J. (2012). Synthesis of pyrazolo[5,1-a]isoquinolines via silver(I)-rhodium(I) cooperative catalysis in the reaction of N'-(2-alkynylbenzylidene)hydrazide with cycloprop-2-ene-1,1-dicarboxylate. Organic & Biomolecular Chemistry, 10(47), 9447-51. https://doi.org/10.1039/c2ob26824h
Yao L, et al. Synthesis of Pyrazolo[5,1-a]isoquinolines Via silver(I)-rhodium(I) Cooperative Catalysis in the Reaction of N'-(2-alkynylbenzylidene)hydrazide With Cycloprop-2-ene-1,1-dicarboxylate. Org Biomol Chem. 2012 Dec 21;10(47):9447-51. PubMed PMID: 23117441.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of pyrazolo[5,1-a]isoquinolines via silver(I)-rhodium(I) cooperative catalysis in the reaction of N'-(2-alkynylbenzylidene)hydrazide with cycloprop-2-ene-1,1-dicarboxylate. AU - Yao,Liangqing, AU - Yu,Xingxin, AU - Mo,Chen, AU - Wu,Jie, Y1 - 2012/11/01/ PY - 2012/11/3/entrez PY - 2012/11/3/pubmed PY - 2013/4/30/medline SP - 9447 EP - 51 JF - Organic & biomolecular chemistry JO - Org Biomol Chem VL - 10 IS - 47 N2 - A tandem reaction between N'-(2-alkynylbenzylidene)hydrazide and cycloprop-2-ene-1,1-dicarboxylate co-catalyzed by silver triflate and tris(triphenylphosphine)rhodium chloride is reported. The reaction proceeds through 6-endo-cyclization, [3 + 2] cycloaddition, cyclopropane opening, and aromatization, leading to pyrazolo[5,1-a]isoquinolines in moderate to good yields. SN - 1477-0539 UR - https://www.unboundmedicine.com/medline/citation/23117441/Synthesis_of_pyrazolo[51_a]isoquinolines_via_silver_I__rhodium_I__cooperative_catalysis_in_the_reaction_of_N'__2_alkynylbenzylidene_hydrazide_with_cycloprop_2_ene_11_dicarboxylate_ L2 - https://doi.org/10.1039/c2ob26824h DB - PRIME DP - Unbound Medicine ER -