Tags

Type your tag names separated by a space and hit enter

Fabrication and characterization of novel antimicrobial films derived from thymol-loaded zein-sodium caseinate (SC) nanoparticles.
J Agric Food Chem. 2012 Nov 21; 60(46):11592-600.JA

Abstract

The objective of this research was to fabricate novel antimicrobial films based on zein colloidal nanoparticles coated with sodium caseinate (SC), an emulsifier/stabilizer. Thymol-loaded zein-SC nanoparticles were prepared using an antisolvent technique, with the average particle size and zeta potential about 200 ± 20 nm and -40 mV, respectively. Zein-SC nanoparticle-based films exhibited higher mechanical resistance and water barrier capacity than the SC films and concomitant good extensibility as compared with zein films. Thymol loadings endowed zein-SC nanoparticle-based films with antimicrobial activity against Escherichia coli and Salmonella as well as DPPH radical scavenging activity. Water vapor permeability, microstructure, mechanical, and controlled release properties of the films were evaluated. The possible relationship between some selected physical properties and microstructure were also discussed. Atomic force microscopy (AFM) analysis indicated that thymol loadings resulted in the emergence phenomena of the nanoparticles to form large particles or packed structure, consisting of clusters of nanoparticles, within the film matrix, in a thymol loading dependent manner. The appearance of large particles or an agglomerate of particles may weaken the compactness of protein network of films and thus impair the water barrier capacity, mechanical resistance, and extensibility of the films. The release kinetics of thymol from nanoparticle-based films can be described as a two-step biphasic process, that is, an initial burst effect followed by subsequent slower release, and zein-SC nanoparticles within the films matrices gave them the ability to sustain the release of thymol. In addition, a schematic illustration of the formation pathway of zein-SC nanoparticle-based films with or without thymol was proposed to illuminate the possible relationship between some selected physical properties and the microstructure of the films.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Li KK
Research and Development Center of Food Proteins, Department of Food Science and Technology, South China University of Technology, Guangzhou 410640, People's Republic of China.
Yin SW
No affiliation info available
Yang XQ
No affiliation info available
Tang CH
No affiliation info available
Wei ZH
No affiliation info available

MeSH

Anti-Bacterial AgentsCaseinsEscherichia coliFood PackagingPlant ExtractsSalmonellaThymolZein

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23121318

Citation

Li, Kang-Kang, et al. "Fabrication and Characterization of Novel Antimicrobial Films Derived From Thymol-loaded Zein-sodium Caseinate (SC) Nanoparticles." Journal of Agricultural and Food Chemistry, vol. 60, no. 46, 2012, pp. 11592-600.
Li KK, Yin SW, Yang XQ, et al. Fabrication and characterization of novel antimicrobial films derived from thymol-loaded zein-sodium caseinate (SC) nanoparticles. J Agric Food Chem. 2012;60(46):11592-600.
Li, K. K., Yin, S. W., Yang, X. Q., Tang, C. H., & Wei, Z. H. (2012). Fabrication and characterization of novel antimicrobial films derived from thymol-loaded zein-sodium caseinate (SC) nanoparticles. Journal of Agricultural and Food Chemistry, 60(46), 11592-600. https://doi.org/10.1021/jf302752v
Li KK, et al. Fabrication and Characterization of Novel Antimicrobial Films Derived From Thymol-loaded Zein-sodium Caseinate (SC) Nanoparticles. J Agric Food Chem. 2012 Nov 21;60(46):11592-600. PubMed PMID: 23121318.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fabrication and characterization of novel antimicrobial films derived from thymol-loaded zein-sodium caseinate (SC) nanoparticles. AU - Li,Kang-Kang, AU - Yin,Shou-Wei, AU - Yang,Xiao-Quan, AU - Tang,Chuan-He, AU - Wei,Zi-Hao, Y1 - 2012/11/09/ PY - 2012/11/6/entrez PY - 2012/11/6/pubmed PY - 2013/11/5/medline SP - 11592 EP - 600 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 60 IS - 46 N2 - The objective of this research was to fabricate novel antimicrobial films based on zein colloidal nanoparticles coated with sodium caseinate (SC), an emulsifier/stabilizer. Thymol-loaded zein-SC nanoparticles were prepared using an antisolvent technique, with the average particle size and zeta potential about 200 ± 20 nm and -40 mV, respectively. Zein-SC nanoparticle-based films exhibited higher mechanical resistance and water barrier capacity than the SC films and concomitant good extensibility as compared with zein films. Thymol loadings endowed zein-SC nanoparticle-based films with antimicrobial activity against Escherichia coli and Salmonella as well as DPPH radical scavenging activity. Water vapor permeability, microstructure, mechanical, and controlled release properties of the films were evaluated. The possible relationship between some selected physical properties and microstructure were also discussed. Atomic force microscopy (AFM) analysis indicated that thymol loadings resulted in the emergence phenomena of the nanoparticles to form large particles or packed structure, consisting of clusters of nanoparticles, within the film matrix, in a thymol loading dependent manner. The appearance of large particles or an agglomerate of particles may weaken the compactness of protein network of films and thus impair the water barrier capacity, mechanical resistance, and extensibility of the films. The release kinetics of thymol from nanoparticle-based films can be described as a two-step biphasic process, that is, an initial burst effect followed by subsequent slower release, and zein-SC nanoparticles within the films matrices gave them the ability to sustain the release of thymol. In addition, a schematic illustration of the formation pathway of zein-SC nanoparticle-based films with or without thymol was proposed to illuminate the possible relationship between some selected physical properties and the microstructure of the films. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/23121318/Fabrication_and_characterization_of_novel_antimicrobial_films_derived_from_thymol_loaded_zein_sodium_caseinate__SC__nanoparticles_ L2 - https://doi.org/10.1021/jf302752v DB - PRIME DP - Unbound Medicine ER -