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Clinical characteristics of high grade foveal hypoplasia.
Int Ophthalmol. 2013 Feb; 33(1):9-14.IO

Abstract

To report clinical characteristics of high grade foveal hypoplasia. Patients with foveal hypoplasia of grade 3 or 4 on spectral domain optical coherence tomography according to a previously published scheme were enrolled. All patients underwent a full ophthalmologic assessment including visual acuity testing, slit lamp biomicroscopy, fundus examination, and evaluation of ocular alignment. The underlying causes of foveal hypoplasia were identified as albinism in five patients and aniridia in six patients. The mean logMAR visual acuity was 0.57 ± 0.24 (range 0.22-1.00) in the right eyes and 0.58 ± 0.21 (range 0.30-1.00) in the left eyes. On fundus examination in patients with albinism, two patients showed marked transparency, one patient showed moderate transparency, and two patients showed minimal transparency. Among six patients with aniridia, five patients showed normal macular pigmentation without macular reflex and one patient showed decreased macular pigmentation with no macular reflex. Patients with high grade macular hypoplasia tended to have poor visual acuities; however, the range of visual acuity was quite variable. Other factors associated with underlying disease could be the reason of this variability. Therefore, careful consideration should be given when assessing visual prognosis in foveal hypoplasia using optical coherence tomography.

Authors+Show Affiliations

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Ilwon-dong, Kangnam-gu, Seoul, Korea.No affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

23124196

Citation

Park, Kyung-Ah, and Sei Yeul Oh. "Clinical Characteristics of High Grade Foveal Hypoplasia." International Ophthalmology, vol. 33, no. 1, 2013, pp. 9-14.
Park KA, Oh SY. Clinical characteristics of high grade foveal hypoplasia. Int Ophthalmol. 2013;33(1):9-14.
Park, K. A., & Oh, S. Y. (2013). Clinical characteristics of high grade foveal hypoplasia. International Ophthalmology, 33(1), 9-14. https://doi.org/10.1007/s10792-012-9664-8
Park KA, Oh SY. Clinical Characteristics of High Grade Foveal Hypoplasia. Int Ophthalmol. 2013;33(1):9-14. PubMed PMID: 23124196.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical characteristics of high grade foveal hypoplasia. AU - Park,Kyung-Ah, AU - Oh,Sei Yeul, Y1 - 2012/11/03/ PY - 2012/06/27/received PY - 2012/10/22/accepted PY - 2012/11/6/entrez PY - 2012/11/6/pubmed PY - 2013/5/10/medline SP - 9 EP - 14 JF - International ophthalmology JO - Int Ophthalmol VL - 33 IS - 1 N2 - To report clinical characteristics of high grade foveal hypoplasia. Patients with foveal hypoplasia of grade 3 or 4 on spectral domain optical coherence tomography according to a previously published scheme were enrolled. All patients underwent a full ophthalmologic assessment including visual acuity testing, slit lamp biomicroscopy, fundus examination, and evaluation of ocular alignment. The underlying causes of foveal hypoplasia were identified as albinism in five patients and aniridia in six patients. The mean logMAR visual acuity was 0.57 ± 0.24 (range 0.22-1.00) in the right eyes and 0.58 ± 0.21 (range 0.30-1.00) in the left eyes. On fundus examination in patients with albinism, two patients showed marked transparency, one patient showed moderate transparency, and two patients showed minimal transparency. Among six patients with aniridia, five patients showed normal macular pigmentation without macular reflex and one patient showed decreased macular pigmentation with no macular reflex. Patients with high grade macular hypoplasia tended to have poor visual acuities; however, the range of visual acuity was quite variable. Other factors associated with underlying disease could be the reason of this variability. Therefore, careful consideration should be given when assessing visual prognosis in foveal hypoplasia using optical coherence tomography. SN - 1573-2630 UR - https://www.unboundmedicine.com/medline/citation/23124196/Clinical_characteristics_of_high_grade_foveal_hypoplasia_ L2 - https://doi.org/10.1007/s10792-012-9664-8 DB - PRIME DP - Unbound Medicine ER -