Relationship between community prevalence of obesity and associated behavioral factors and community rates of influenza-related hospitalizations in the United States.
Abstract
BACKGROUND
Findings from studies examining the association between obesity and acute respiratory infection are inconsistent. Few studies have assessed the relationship between obesity-related behavioral factors, such as diet and exercise, and risk of acute respiratory infection.OBJECTIVE
To determine whether community prevalence of obesity, low fruit/vegetable consumption, and physical inactivity are associated with influenza-related hospitalization rates.METHODS
Using data from 274 US counties, from 2002 to 2008, we regressed county influenza-related hospitalization rates on county prevalence of obesity (BMI ≥ 30), low fruit/vegetable consumption (<5 servings/day), and physical inactivity (<30 minutes/month recreational exercise), while adjusting for community-level confounders such as insurance coverage and the number of primary care physicians per 100,000 population.RESULTS
A 5% increase in obesity prevalence was associated with a 12% increase in influenza-related hospitalization rates [adjusted rate ratio (ARR) 1.12, 95% confidence interval (CI) 1.07, 1.17]. Similarly, a 5% increase in the prevalence of low fruit/vegetable consumption and physical inactivity was associated with an increase of 12% (ARR 1.12, 95% CI 1.08, 1.17) and 11% (ARR 1.11, 95% CI 1.07, 1.16), respectively. When all three variables were included in the same model, a 5% increase in prevalence of obesity, low fruit/vegetable consumption, and physical inactivity was associated with 6%, 8%, and 7% increases in influenza-related hospitalization rates, respectively.CONCLUSIONS
Communities with a greater prevalence of obesity were more likely to have high influenza-related hospitalization rates. Similarly, less physically active populations, with lower fruit/vegetable consumption, tended to have higher influenza-related hospitalization rates, even after accounting for obesity.Links
Authors+Show Affiliations
,Children's Hospital Informatics Program, Children's Hospital Boston, Boston, MA, USA. katia.charland@mcgill.ca
, , , , ,Source
Influenza and other respiratory viruses 7:5 2013 Sep pg 718-28
MeSH
AdolescentAdult
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Fruit
Hospitalization
Humans
Infant
Influenza, Human
Male
Middle Aged
Motor Activity
Obesity
Residence Characteristics
United States
Vegetables
Young Adult
Pub Type(s)
Journal ArticleResearch Support, U.S. Gov't, Non-P.H.S.
Language
eng
PubMed ID
23136926
Citation
* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Relationship between community prevalence of obesity and associated behavioral factors and community rates of influenza-related hospitalizations in the United States.
AU - Charland,Katia M,
AU - Buckeridge,David L,
AU - Hoen,Anne G,
AU - Berry,Jay G,
AU - Elixhauser,Anne,
AU - Melton,Forrest,
AU - Brownstein,John S,
Y1 - 2012/11/08/
PY - 2012/11/10/entrez
PY - 2012/11/10/pubmed
PY - 2014/3/13/medline
KW - Diet
KW - exercise
KW - influenza
KW - influenza-like illness
KW - obesity
SP - 718
EP - 28
JF - Influenza and other respiratory viruses
JO - Influenza Other Respir Viruses
VL - 7
IS - 5
N2 - BACKGROUND: Findings from studies examining the association between obesity and acute respiratory infection are inconsistent. Few studies have assessed the relationship between obesity-related behavioral factors, such as diet and exercise, and risk of acute respiratory infection. OBJECTIVE: To determine whether community prevalence of obesity, low fruit/vegetable consumption, and physical inactivity are associated with influenza-related hospitalization rates. METHODS: Using data from 274 US counties, from 2002 to 2008, we regressed county influenza-related hospitalization rates on county prevalence of obesity (BMI ≥ 30), low fruit/vegetable consumption (<5 servings/day), and physical inactivity (<30 minutes/month recreational exercise), while adjusting for community-level confounders such as insurance coverage and the number of primary care physicians per 100,000 population. RESULTS: A 5% increase in obesity prevalence was associated with a 12% increase in influenza-related hospitalization rates [adjusted rate ratio (ARR) 1.12, 95% confidence interval (CI) 1.07, 1.17]. Similarly, a 5% increase in the prevalence of low fruit/vegetable consumption and physical inactivity was associated with an increase of 12% (ARR 1.12, 95% CI 1.08, 1.17) and 11% (ARR 1.11, 95% CI 1.07, 1.16), respectively. When all three variables were included in the same model, a 5% increase in prevalence of obesity, low fruit/vegetable consumption, and physical inactivity was associated with 6%, 8%, and 7% increases in influenza-related hospitalization rates, respectively. CONCLUSIONS: Communities with a greater prevalence of obesity were more likely to have high influenza-related hospitalization rates. Similarly, less physically active populations, with lower fruit/vegetable consumption, tended to have higher influenza-related hospitalization rates, even after accounting for obesity.
SN - 1750-2659
UR - https://www.unboundmedicine.com/medline/citation/23136926/full_citation
L2 - https://doi.org/10.1111/irv.12019
DB - PRIME
DP - Unbound Medicine
ER -