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Outcomes after temporal lobectomy for temporal lobe epilepsy with hippocampal sclerosis.
J Med Assoc Thai 2012; 95(9):1173-7JM

Abstract

OBJECTIVE

Outcome predictors from the pure cohorts of patients with temporal lobe epilepsy (TLE) with hippocampal sclerosis (HS) are limited The aim of the present study was to assess seizure outcomes and predictive factors in groups of well-defined patients with TLE-HS.

MATERIAL AND METHOD

One hundred forty eight patients with drug resistant TLE who had magnetic resonance imaging (MRI) that demonstrated unilateral HS underwent temporal lobectomy between 2004 and 2008 by a single neurosurgeon. All patients had completed at least two years of follow-up. Seizure outcome was categorized into seizure-free and not seizure-free.

RESULTS

Ninety-five patients (64.2%) were seizure-free after surgery at two years of follow-up. At four years follow-up, 47 patients (77.1%) were seizure-free for at least two years. There was no operative mortality or significant morbidity. No clinical variables are predictive of surgical outcomes at two and four years offollow-up.

CONCLUSION

Temporal lobectomy for drug-resistant TLE with HS is safe and effective. The authors did not identify predictive factors of surgical outcomes in TLE-HS.

Authors+Show Affiliations

Department of Neurosurgery, Prasat Neurological Institute, Bangkok, Thailand. srikijt@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23140034

Citation

Srikijvilaikul, Teeradej, et al. "Outcomes After Temporal Lobectomy for Temporal Lobe Epilepsy With Hippocampal Sclerosis." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 95, no. 9, 2012, pp. 1173-7.
Srikijvilaikul T, Lerdlum S, Tepmongkol S, et al. Outcomes after temporal lobectomy for temporal lobe epilepsy with hippocampal sclerosis. J Med Assoc Thai. 2012;95(9):1173-7.
Srikijvilaikul, T., Lerdlum, S., Tepmongkol, S., & Shuangshoti, S. (2012). Outcomes after temporal lobectomy for temporal lobe epilepsy with hippocampal sclerosis. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 95(9), pp. 1173-7.
Srikijvilaikul T, et al. Outcomes After Temporal Lobectomy for Temporal Lobe Epilepsy With Hippocampal Sclerosis. J Med Assoc Thai. 2012;95(9):1173-7. PubMed PMID: 23140034.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcomes after temporal lobectomy for temporal lobe epilepsy with hippocampal sclerosis. AU - Srikijvilaikul,Teeradej, AU - Lerdlum,Sukulya, AU - Tepmongkol,Supatporn, AU - Shuangshoti,Shanop, PY - 2012/11/13/entrez PY - 2012/11/13/pubmed PY - 2012/12/12/medline SP - 1173 EP - 7 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 95 IS - 9 N2 - OBJECTIVE: Outcome predictors from the pure cohorts of patients with temporal lobe epilepsy (TLE) with hippocampal sclerosis (HS) are limited The aim of the present study was to assess seizure outcomes and predictive factors in groups of well-defined patients with TLE-HS. MATERIAL AND METHOD: One hundred forty eight patients with drug resistant TLE who had magnetic resonance imaging (MRI) that demonstrated unilateral HS underwent temporal lobectomy between 2004 and 2008 by a single neurosurgeon. All patients had completed at least two years of follow-up. Seizure outcome was categorized into seizure-free and not seizure-free. RESULTS: Ninety-five patients (64.2%) were seizure-free after surgery at two years of follow-up. At four years follow-up, 47 patients (77.1%) were seizure-free for at least two years. There was no operative mortality or significant morbidity. No clinical variables are predictive of surgical outcomes at two and four years offollow-up. CONCLUSION: Temporal lobectomy for drug-resistant TLE with HS is safe and effective. The authors did not identify predictive factors of surgical outcomes in TLE-HS. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/23140034/Outcomes_after_temporal_lobectomy_for_temporal_lobe_epilepsy_with_hippocampal_sclerosis_ L2 - http://www.diseaseinfosearch.org/result/2593 DB - PRIME DP - Unbound Medicine ER -