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Citalopram versus psychological training for depression and anxiety symptoms in hemodialysis patients.
Iran J Kidney Dis 2012; 6(6):446-51IJ

Abstract

INTRODUCTION

This study was designed to compare an antidepressant medication, citalopram, with psychological training in hemodialysis patients with symptoms of anxiety and depression.

MATERIALS AND METHODS

A total number of 44 hemodialysis patients scored 8 and more on the Hospital Anxiety and Depression Scale (HADS) were randomly allocated to two groups to receive citalopram, 20 mg/d, for 3 months or to attend 6 sessions of 1-hour psychological training. A nephrologist and a senior psychiatry resident were responsible for training of the patients, which contained explaining the anatomy of the kidneys, causes of kidney failure, treatment modalities, the mechanism involved in hemodialysis, the required care in hemodialysis patients, stages of adaptive reaction in human, and techniques of problem solving, stress management, and muscle relaxation. Both groups completed the HADS once before and once after the treatment. The final results of the two groups were compared.

RESULTS

Citalopram administration led to a significant decrease in the patients' depression score (P = .001), anxiety score (P = .048), and total HADS score (P = .002). Psychological training sessions also decreased significantly depression (P = .04), anxiety (P = .03), and total HADS scores (P = .045). There was no significant difference in the amount of decrease in the scores of depression (P = .65), anxiety (P = .19), and the total HADS (P = .66) between the two groups.

CONCLUSIONS

Psychological training and citalopram have similar effects on improving the symptoms of anxiety and depression in hemodialysis patients.

Authors+Show Affiliations

Department of Psychiatry, Faculty of Medicine, Psychiatry and Behavioral Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23146983

Citation

Hosseini, Seyed Hamzeh, et al. "Citalopram Versus Psychological Training for Depression and Anxiety Symptoms in Hemodialysis Patients." Iranian Journal of Kidney Diseases, vol. 6, no. 6, 2012, pp. 446-51.
Hosseini SH, Espahbodi F, Mirzadeh Goudarzi SM. Citalopram versus psychological training for depression and anxiety symptoms in hemodialysis patients. Iran J Kidney Dis. 2012;6(6):446-51.
Hosseini, S. H., Espahbodi, F., & Mirzadeh Goudarzi, S. M. (2012). Citalopram versus psychological training for depression and anxiety symptoms in hemodialysis patients. Iranian Journal of Kidney Diseases, 6(6), pp. 446-51.
Hosseini SH, Espahbodi F, Mirzadeh Goudarzi SM. Citalopram Versus Psychological Training for Depression and Anxiety Symptoms in Hemodialysis Patients. Iran J Kidney Dis. 2012;6(6):446-51. PubMed PMID: 23146983.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Citalopram versus psychological training for depression and anxiety symptoms in hemodialysis patients. AU - Hosseini,Seyed Hamzeh, AU - Espahbodi,Fatemeh, AU - Mirzadeh Goudarzi,Seyyed Mohammad Mehdi, PY - 2012/02/06/received PY - 2012/07/06/accepted PY - 2012/11/14/entrez PY - 2012/11/14/pubmed PY - 2013/5/2/medline SP - 446 EP - 51 JF - Iranian journal of kidney diseases JO - Iran J Kidney Dis VL - 6 IS - 6 N2 - INTRODUCTION: This study was designed to compare an antidepressant medication, citalopram, with psychological training in hemodialysis patients with symptoms of anxiety and depression. MATERIALS AND METHODS: A total number of 44 hemodialysis patients scored 8 and more on the Hospital Anxiety and Depression Scale (HADS) were randomly allocated to two groups to receive citalopram, 20 mg/d, for 3 months or to attend 6 sessions of 1-hour psychological training. A nephrologist and a senior psychiatry resident were responsible for training of the patients, which contained explaining the anatomy of the kidneys, causes of kidney failure, treatment modalities, the mechanism involved in hemodialysis, the required care in hemodialysis patients, stages of adaptive reaction in human, and techniques of problem solving, stress management, and muscle relaxation. Both groups completed the HADS once before and once after the treatment. The final results of the two groups were compared. RESULTS: Citalopram administration led to a significant decrease in the patients' depression score (P = .001), anxiety score (P = .048), and total HADS score (P = .002). Psychological training sessions also decreased significantly depression (P = .04), anxiety (P = .03), and total HADS scores (P = .045). There was no significant difference in the amount of decrease in the scores of depression (P = .65), anxiety (P = .19), and the total HADS (P = .66) between the two groups. CONCLUSIONS: Psychological training and citalopram have similar effects on improving the symptoms of anxiety and depression in hemodialysis patients. SN - 1735-8604 UR - https://www.unboundmedicine.com/medline/citation/23146983/Citalopram_versus_psychological_training_for_depression_and_anxiety_symptoms_in_hemodialysis_patients_ L2 - http://www.ijkd.org/index.php/ijkd/article/view/770/476 DB - PRIME DP - Unbound Medicine ER -