TY - JOUR T1 - CE-MS for metabolomics: developments and applications in the period 2010-2012. AU - Ramautar,Rawi, AU - Somsen,Govert W, AU - de Jong,Gerhardus J, Y1 - 2012/12/03/ PY - 2012/07/20/received PY - 2012/08/30/revised PY - 2012/08/30/accepted PY - 2012/11/20/entrez PY - 2012/11/20/pubmed PY - 2013/6/5/medline SP - 86 EP - 98 JF - Electrophoresis JO - Electrophoresis VL - 34 IS - 1 N2 - CE-MS has emerged as a powerful technique for the profiling of (highly) polar and charged metabolites in biological samples. This review provides an update of the most recent developments in CE-MS for metabolomics covering the scientific literature from July 2010 to June 2012. The present paper is an update of two previous review papers covering the years 2000-2010 (Electrophoresis 2009, 30, 276-291; Electrophoresis 2011, 32, 52-65). Emerging technological developments used in CE-MS for metabolomics are discussed, such as the use of novel interfacing techniques for coupling CE to MS. Representative examples illustrate the applicability of CE-MS in the fields of biomedical, clinical, microbial, plant, environmental and food metabolomics. Concerning targeted and non-targeted approaches, a comprehensive overview of recent CE-MS-based metabolomics studies is given in a table. Information on sample type and pretreatment, capillary coatings and MS detection mode is provided. Finally, general conclusions and perspectives are provided. SN - 1522-2683 UR - https://www.unboundmedicine.com/medline/citation/23161106/CE_MS_for_metabolomics:_developments_and_applications_in_the_period_2010_2012_ L2 - https://doi.org/10.1002/elps.201200390 DB - PRIME DP - Unbound Medicine ER -