Tags

Type your tag names separated by a space and hit enter

Primary spinal primitive neuroectodermal tumour: report of two cases mimicking neurofibroma and review of the literature.
Neurol Neurochir Pol. 2012 Sep-Oct; 46(5):480-8.NN

Abstract

Primary spinal primitive neuroectodermal tumours (PNETs) are a rare entity. Most of them occur in children and young adults. To date, 47 cases of primary spinal PNET have been reported in the literature. We present two cases of primary spinal PNET. In both cases, the tumours were thoracic extradural ones with intrathoracic extension through intervertebral foramina resembling neurofibroma. These tumours are highly aggressive with rapid growth as evidenced by the short history in both of our cases. Both cases underwent gross total removal of the intraspinal and thoracic components. Postoperatively, both patients underwent cranio-spinal radiotherapy. A review of the literature shows that the overall prognosis of PNETs of the spinal cord is very poor even with adequate surgery, radiotherapy and chemotherapy. One patient died after 4 months and the other one is still alive 8 months after surgery, radiotherapy and chemotherapy.

Authors+Show Affiliations

SCB Medical College, Manglabag 753007, Cuttack, India. dr_ash@yahoo.co.inNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

23161193

Citation

Patnaik, Ashis, et al. "Primary Spinal Primitive Neuroectodermal Tumour: Report of Two Cases Mimicking Neurofibroma and Review of the Literature." Neurologia I Neurochirurgia Polska, vol. 46, no. 5, 2012, pp. 480-8.
Patnaik A, Mishra S, Mishra S, et al. Primary spinal primitive neuroectodermal tumour: report of two cases mimicking neurofibroma and review of the literature. Neurol Neurochir Pol. 2012;46(5):480-8.
Patnaik, A., Mishra, S., Mishra, S., & Deo, R. (2012). Primary spinal primitive neuroectodermal tumour: report of two cases mimicking neurofibroma and review of the literature. Neurologia I Neurochirurgia Polska, 46(5), 480-8.
Patnaik A, et al. Primary Spinal Primitive Neuroectodermal Tumour: Report of Two Cases Mimicking Neurofibroma and Review of the Literature. Neurol Neurochir Pol. 2012 Sep-Oct;46(5):480-8. PubMed PMID: 23161193.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Primary spinal primitive neuroectodermal tumour: report of two cases mimicking neurofibroma and review of the literature. AU - Patnaik,Ashis, AU - Mishra,Sudhansu, AU - Mishra,Sanjib, AU - Deo,Rama, PY - 2012/11/20/entrez PY - 2012/11/20/pubmed PY - 2013/3/2/medline SP - 480 EP - 8 JF - Neurologia i neurochirurgia polska JO - Neurol Neurochir Pol VL - 46 IS - 5 N2 - Primary spinal primitive neuroectodermal tumours (PNETs) are a rare entity. Most of them occur in children and young adults. To date, 47 cases of primary spinal PNET have been reported in the literature. We present two cases of primary spinal PNET. In both cases, the tumours were thoracic extradural ones with intrathoracic extension through intervertebral foramina resembling neurofibroma. These tumours are highly aggressive with rapid growth as evidenced by the short history in both of our cases. Both cases underwent gross total removal of the intraspinal and thoracic components. Postoperatively, both patients underwent cranio-spinal radiotherapy. A review of the literature shows that the overall prognosis of PNETs of the spinal cord is very poor even with adequate surgery, radiotherapy and chemotherapy. One patient died after 4 months and the other one is still alive 8 months after surgery, radiotherapy and chemotherapy. SN - 0028-3843 UR - https://www.unboundmedicine.com/medline/citation/23161193/Primary_spinal_primitive_neuroectodermal_tumour:_report_of_two_cases_mimicking_neurofibroma_and_review_of_the_literature_ L2 - http://www.diseaseinfosearch.org/result/5170 DB - PRIME DP - Unbound Medicine ER -