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Clear cell acanthoma.
Clin Exp Dermatol. 2012 Dec; 37(8):831-7.CE

Abstract

Clear cell acanthoma (CCA), is an asymptomatic benign lesion of unknown origin and aetiology, which typically presents as a red to brown, dome-shaped papule on the leg. We discuss the case of a patient with an irregular plaque of hypopigmented papules whose diagnosis of CCA was only made by biopsy, and review the characteristic presentation, uncommon variants, locations and associated conditions of this lesion. The diagnosis is based on histopathology and/or immunohistochemistry, but the variable clinical presentation may make diagnosis difficult. The differential diagnosis includes skin tumours and inflammatory and pigmentary dermatoses. The lesions do not regress spontaneously, and excisional removal is the preferred treatment.

Authors+Show Affiliations

Department of Paediatrics, Chulalongkorn University, Bangkok, Thailand.No affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

23171155

Citation

Tempark, T, and T Shwayder. "Clear Cell Acanthoma." Clinical and Experimental Dermatology, vol. 37, no. 8, 2012, pp. 831-7.
Tempark T, Shwayder T. Clear cell acanthoma. Clin Exp Dermatol. 2012;37(8):831-7.
Tempark, T., & Shwayder, T. (2012). Clear cell acanthoma. Clinical and Experimental Dermatology, 37(8), 831-7. https://doi.org/10.1111/j.1365-2230.2012.04428.x
Tempark T, Shwayder T. Clear Cell Acanthoma. Clin Exp Dermatol. 2012;37(8):831-7. PubMed PMID: 23171155.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clear cell acanthoma. AU - Tempark,T, AU - Shwayder,T, PY - 2012/11/23/entrez PY - 2012/11/23/pubmed PY - 2013/5/3/medline SP - 831 EP - 7 JF - Clinical and experimental dermatology JO - Clin. Exp. Dermatol. VL - 37 IS - 8 N2 - Clear cell acanthoma (CCA), is an asymptomatic benign lesion of unknown origin and aetiology, which typically presents as a red to brown, dome-shaped papule on the leg. We discuss the case of a patient with an irregular plaque of hypopigmented papules whose diagnosis of CCA was only made by biopsy, and review the characteristic presentation, uncommon variants, locations and associated conditions of this lesion. The diagnosis is based on histopathology and/or immunohistochemistry, but the variable clinical presentation may make diagnosis difficult. The differential diagnosis includes skin tumours and inflammatory and pigmentary dermatoses. The lesions do not regress spontaneously, and excisional removal is the preferred treatment. SN - 1365-2230 UR - https://www.unboundmedicine.com/medline/citation/23171155/Clear_cell_acanthoma_ L2 - https://doi.org/10.1111/j.1365-2230.2012.04428.x DB - PRIME DP - Unbound Medicine ER -