Abstract
A man in his 60s with a history of multiple myeloma diagnosed 6 months previously was referred with a diagnosis of a sellar mass. He reported a 3-month history of headaches associated with double vision which appeared to improve with corticosteroid treatment. An MRI scan revealed a 3.7 cm × 3 cm × 2.6 cm sellar mass with erosion into the sphenoid sinus and extending to the right cavernous sinus. Pituitary function tests were normal apart from hypogonadotrophic hypogonadism. A diagnosis of plasmacytoma was considered and so transphenoidal biopsy of the sellar lesion was organised, which revealed sheets of mature appearing plasma cells, staining exclusively for κ-light chain immunoglobulins. He was to be started on chemotherapy for the myeloma and radiotherapy for the plasmacytoma. The patient's clinical course was complicated by community-acquired pneumonia and renal failure resulting in his death a month after the diagnosis of plasmacytoma.
TY - JOUR
T1 - Metastatic haematological malignancy presenting as a sellar mass.
AU - Udiawar,Maneesh,
AU - Bejnariu,Christina,
AU - Davies,Stephen,
Y1 - 2012/11/21/
PY - 2012/11/24/entrez
PY - 2012/11/24/pubmed
PY - 2014/1/22/medline
JF - BMJ case reports
JO - BMJ Case Rep
VL - 2012
N2 - A man in his 60s with a history of multiple myeloma diagnosed 6 months previously was referred with a diagnosis of a sellar mass. He reported a 3-month history of headaches associated with double vision which appeared to improve with corticosteroid treatment. An MRI scan revealed a 3.7 cm × 3 cm × 2.6 cm sellar mass with erosion into the sphenoid sinus and extending to the right cavernous sinus. Pituitary function tests were normal apart from hypogonadotrophic hypogonadism. A diagnosis of plasmacytoma was considered and so transphenoidal biopsy of the sellar lesion was organised, which revealed sheets of mature appearing plasma cells, staining exclusively for κ-light chain immunoglobulins. He was to be started on chemotherapy for the myeloma and radiotherapy for the plasmacytoma. The patient's clinical course was complicated by community-acquired pneumonia and renal failure resulting in his death a month after the diagnosis of plasmacytoma.
SN - 1757-790X
UR - https://www.unboundmedicine.com/medline/citation/23175000/Metastatic_haematological_malignancy_presenting_as_a_sellar_mass_
L2 - https://casereports.bmj.com/lookup/pmidlookup?view=long&pmid=23175000
DB - PRIME
DP - Unbound Medicine
ER -
