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Polycystic ovarian syndrome management options.
Obstet Gynecol Clin North Am. 2012 Dec; 39(4):495-506.OG

Abstract

Polycystic ovarian syndrome (PCOS) is a disorder of androgen excess and ovarian dysfunction. Hirsutism and elevated free testosterone levels are the most consistent signs of the androgen excess. Irregular, infrequent, or absent menses and infertility are symptoms of ovulatory dysfunction. Obesity is also a feature of this syndrome and contributes to associated metabolic abnormalities. Lifestyle modification should be the first treatment and is effective in reducing the signs and symptoms. The ovulatory infertility associated with PCOS can be overcome in most cases with oral (clomiphene citrate or letrozole) or injectable (gonadotropins) agents. Surgical intervention is reserved for cases resistant to medical management.

Links

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linkinghub.elsevier.com
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Authors+Show Affiliations

Bates GW
Department of Obstetrics and Gynecology, University of Alabama School of Medicine, 619 19th Street South, Building 176F, Room 10390, Birmingham, AL 35249-7333, USA. wbates@uab.edu
Propst AM
No affiliation info available

MeSH

ClomipheneContraceptives, Oral, HormonalEstrogen AntagonistsExerciseFemaleHumansInfertility, FemaleInsulin ResistanceLetrozoleMenstruation DisturbancesMetforminNitrilesObesityOvulation InductionPolycystic Ovary SyndromeReproductive Techniques, AssistedRisk Reduction BehaviorTriazolesWeight Loss

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23182556

Citation

Bates, G Wright, and Anthony M. Propst. "Polycystic Ovarian Syndrome Management Options." Obstetrics and Gynecology Clinics of North America, vol. 39, no. 4, 2012, pp. 495-506.
Bates GW, Propst AM. Polycystic ovarian syndrome management options. Obstet Gynecol Clin North Am. 2012;39(4):495-506.
Bates, G. W., & Propst, A. M. (2012). Polycystic ovarian syndrome management options. Obstetrics and Gynecology Clinics of North America, 39(4), 495-506. https://doi.org/10.1016/j.ogc.2012.10.001
Bates GW, Propst AM. Polycystic Ovarian Syndrome Management Options. Obstet Gynecol Clin North Am. 2012;39(4):495-506. PubMed PMID: 23182556.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Polycystic ovarian syndrome management options. AU - Bates,G Wright,Jr AU - Propst,Anthony M, PY - 2012/11/28/entrez PY - 2012/11/28/pubmed PY - 2013/6/13/medline SP - 495 EP - 506 JF - Obstetrics and gynecology clinics of North America JO - Obstet Gynecol Clin North Am VL - 39 IS - 4 N2 - Polycystic ovarian syndrome (PCOS) is a disorder of androgen excess and ovarian dysfunction. Hirsutism and elevated free testosterone levels are the most consistent signs of the androgen excess. Irregular, infrequent, or absent menses and infertility are symptoms of ovulatory dysfunction. Obesity is also a feature of this syndrome and contributes to associated metabolic abnormalities. Lifestyle modification should be the first treatment and is effective in reducing the signs and symptoms. The ovulatory infertility associated with PCOS can be overcome in most cases with oral (clomiphene citrate or letrozole) or injectable (gonadotropins) agents. Surgical intervention is reserved for cases resistant to medical management. SN - 1558-0474 UR - https://www.unboundmedicine.com/medline/citation/23182556/Polycystic_ovarian_syndrome_management_options_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0889-8545(12)00082-4 DB - PRIME DP - Unbound Medicine ER -