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Perforated gastrointestinal stromal tumor in the jejunum: A rare cause of acute abdomen.
Oncol Lett. 2012 Dec; 4(6):1244-1246.OL

Abstract

Gastrointestinal stromal tumors (GIST) are highly frequent mesenchymal tumors of the digestive tract, which mainly affect the stomach and small intestine. GISTs frequently exist with unclear symptoms. Their initial clinical presentation as acute abdomen due to their perforation is particularly rare. In the present study we report a case of a 59-year-old male presenting with acute abdomen. The final diagnosis revealed a small bowel perforation due to GIST. In this paper, we report the clinical manifestation as well as computed tomography and histopathological findings helpful for the accurate diagnosis of this rare complication of GIST. Emergency laparotomy and complete resection of tumor are essential. Following surgical resection, adjuvant tyrosine kinase inhibitor therapy should be considered for prevention of early recurrence.

Authors+Show Affiliations

Departments of General Surgery and.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23197998

Citation

Memmi, Naim, et al. "Perforated Gastrointestinal Stromal Tumor in the Jejunum: a Rare Cause of Acute Abdomen." Oncology Letters, vol. 4, no. 6, 2012, pp. 1244-1246.
Memmi N, Cipe G, Bektasoglu H, et al. Perforated gastrointestinal stromal tumor in the jejunum: A rare cause of acute abdomen. Oncol Lett. 2012;4(6):1244-1246.
Memmi, N., Cipe, G., Bektasoglu, H., Toydemir, T., Kadioglu, H., Bozkurt, S., Buyukpinarbasili, N., Karatepe, O., & Muslumanoglu, M. (2012). Perforated gastrointestinal stromal tumor in the jejunum: A rare cause of acute abdomen. Oncology Letters, 4(6), 1244-1246.
Memmi N, et al. Perforated Gastrointestinal Stromal Tumor in the Jejunum: a Rare Cause of Acute Abdomen. Oncol Lett. 2012;4(6):1244-1246. PubMed PMID: 23197998.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Perforated gastrointestinal stromal tumor in the jejunum: A rare cause of acute abdomen. AU - Memmi,Naim, AU - Cipe,Gokhan, AU - Bektasoglu,Huseyin, AU - Toydemir,Toygar, AU - Kadioglu,Huseyin, AU - Bozkurt,Suleyman, AU - Buyukpinarbasili,Nur, AU - Karatepe,Oguzhan, AU - Muslumanoglu,Mahmut, Y1 - 2012/09/14/ PY - 2012/05/24/received PY - 2012/08/21/accepted PY - 2012/12/1/entrez PY - 2012/12/1/pubmed PY - 2012/12/1/medline SP - 1244 EP - 1246 JF - Oncology letters JO - Oncol Lett VL - 4 IS - 6 N2 - Gastrointestinal stromal tumors (GIST) are highly frequent mesenchymal tumors of the digestive tract, which mainly affect the stomach and small intestine. GISTs frequently exist with unclear symptoms. Their initial clinical presentation as acute abdomen due to their perforation is particularly rare. In the present study we report a case of a 59-year-old male presenting with acute abdomen. The final diagnosis revealed a small bowel perforation due to GIST. In this paper, we report the clinical manifestation as well as computed tomography and histopathological findings helpful for the accurate diagnosis of this rare complication of GIST. Emergency laparotomy and complete resection of tumor are essential. Following surgical resection, adjuvant tyrosine kinase inhibitor therapy should be considered for prevention of early recurrence. SN - 1792-1074 UR - https://www.unboundmedicine.com/medline/citation/23197998/Perforated_gastrointestinal_stromal_tumor_in_the_jejunum:_A_rare_cause_of_acute_abdomen_ L2 - https://www.ingentaconnect.com/openurl?genre=article&issn=1792-1074&volume=4&issue=6&spage=1244&aulast=Memmi DB - PRIME DP - Unbound Medicine ER -