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Long-term intraventricular infusion of morphine for intractable pain in cancer of the head and neck.
Neurosurgery. 1990 Mar; 26(3):404-7; discussion 407-8.N

Abstract

The authors' experience with seven patients with intractable pain that was treated by continuous intraventricular infusion of morphine through an implanted Infusaid pump is reported. The pain was caused by head and neck cancer in six patients and was associated with postpolio syndrome in one. The average follow-up was 7 months. Pain was effectively managed through intraventricular administration of a combination of morphine and mild oral narcotic analgesics. Complications included one case of transient respiratory depression, one pump pocket infection, and one pump failure. The morphine dose required to maintain analgesia increased over time in all patients treated. This is a safe and effective method of pain management in patients with head and neck cancer. It is useful as well in patients who have intractable pain that cannot be managed through an intrathecal route because of a contraindication to lumbar puncture or an inaccessible subarachnoid space.

Authors+Show Affiliations

Dennis GC
Department of Surgery, College of Medicine, Howard University, Washington, District of Columbia.
DeWitty RL
No affiliation info available

MeSH

Head and Neck NeoplasmsHumansInfusion PumpsInjections, IntraventricularMorphinePain, Intractable

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2320208

Citation

Dennis, G C., and R L. DeWitty. "Long-term Intraventricular Infusion of Morphine for Intractable Pain in Cancer of the Head and Neck." Neurosurgery, vol. 26, no. 3, 1990, pp. 404-7; discussion 407-8.
Dennis GC, DeWitty RL. Long-term intraventricular infusion of morphine for intractable pain in cancer of the head and neck. Neurosurgery. 1990;26(3):404-7; discussion 407-8.
Dennis, G. C., & DeWitty, R. L. (1990). Long-term intraventricular infusion of morphine for intractable pain in cancer of the head and neck. Neurosurgery, 26(3), 404-7; discussion 407-8.
Dennis GC, DeWitty RL. Long-term Intraventricular Infusion of Morphine for Intractable Pain in Cancer of the Head and Neck. Neurosurgery. 1990;26(3):404-7; discussion 407-8. PubMed PMID: 2320208.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term intraventricular infusion of morphine for intractable pain in cancer of the head and neck. AU - Dennis,G C, AU - DeWitty,R L, PY - 1990/3/1/pubmed PY - 1990/3/1/medline PY - 1990/3/1/entrez SP - 404-7; discussion 407-8 JF - Neurosurgery JO - Neurosurgery VL - 26 IS - 3 N2 - The authors' experience with seven patients with intractable pain that was treated by continuous intraventricular infusion of morphine through an implanted Infusaid pump is reported. The pain was caused by head and neck cancer in six patients and was associated with postpolio syndrome in one. The average follow-up was 7 months. Pain was effectively managed through intraventricular administration of a combination of morphine and mild oral narcotic analgesics. Complications included one case of transient respiratory depression, one pump pocket infection, and one pump failure. The morphine dose required to maintain analgesia increased over time in all patients treated. This is a safe and effective method of pain management in patients with head and neck cancer. It is useful as well in patients who have intractable pain that cannot be managed through an intrathecal route because of a contraindication to lumbar puncture or an inaccessible subarachnoid space. SN - 0148-396X UR - https://www.unboundmedicine.com/medline/citation/2320208/Long_term_intraventricular_infusion_of_morphine_for_intractable_pain_in_cancer_of_the_head_and_neck_ DB - PRIME DP - Unbound Medicine ER -