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Evaluation of diverse antioxidant activities of Galium aparine.
Spectrochim Acta A Mol Biomol Spectrosc. 2013 Feb; 102:24-9.SA

Abstract

Methanol extract and its n-hexane, ethyl acetate, butanol and aqueous fraction of Galium aparine L. (Rubiacea) were evaluated in vitro for their antioxidant capacity (DPPH, superoxide radical, phosphomolybdate assay); reducing power (ABTS, hydroxyl, hydrogen peroxide, to reduce Fe(3+) to Fe(2+) ions) and to estimate total flavonoid and phenolic contents. All the free radical generating assay models depicted differential positive scavenging activity but considerable magnitude for all the fractions. The results showed that aqueous fraction strongly scavenge the DPPH, ABTS, hydroxyl, hydrogen peroxide and superoxide radicals. A significantly high correlation coefficient existed between IC(50) values of DPPH and superoxide radical with total phenolic content and phosphomolybdate assay with total flavonoid contents, respectively. These results suggested that aqueous fraction can be a good source of antioxidant therapeutic in oxidative stress damages.

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Authors+Show Affiliations

Bokhari J
Department of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan. jasiabokhari@yahoo.com
Khan MR
No affiliation info available
Shabbir M
No affiliation info available
Rashid U
No affiliation info available
Jan S
No affiliation info available
Zai JA
No affiliation info available

MeSH

AntioxidantsBenzothiazolesBiphenyl CompoundsFlavonoidsHydrogen PeroxideHydroxyl RadicalOxidation-ReductionPhenolsPicratesPlant ExtractsRubiaceaeSulfonic AcidsSuperoxidesThiazoles

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23211618

Citation

Bokhari, Jasia, et al. "Evaluation of Diverse Antioxidant Activities of Galium Aparine." Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, vol. 102, 2013, pp. 24-9.
Bokhari J, Khan MR, Shabbir M, et al. Evaluation of diverse antioxidant activities of Galium aparine. Spectrochim Acta A Mol Biomol Spectrosc. 2013;102:24-9.
Bokhari, J., Khan, M. R., Shabbir, M., Rashid, U., Jan, S., & Zai, J. A. (2013). Evaluation of diverse antioxidant activities of Galium aparine. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 102, 24-9. https://doi.org/10.1016/j.saa.2012.09.056
Bokhari J, et al. Evaluation of Diverse Antioxidant Activities of Galium Aparine. Spectrochim Acta A Mol Biomol Spectrosc. 2013;102:24-9. PubMed PMID: 23211618.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of diverse antioxidant activities of Galium aparine. AU - Bokhari,Jasia, AU - Khan,Muhammad R, AU - Shabbir,Maria, AU - Rashid,Umbreen, AU - Jan,Shumaila, AU - Zai,Jawaid A, Y1 - 2012/10/13/ PY - 2012/06/13/received PY - 2012/09/10/revised PY - 2012/09/20/accepted PY - 2012/12/6/entrez PY - 2012/12/6/pubmed PY - 2013/6/14/medline SP - 24 EP - 9 JF - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy JO - Spectrochim Acta A Mol Biomol Spectrosc VL - 102 N2 - Methanol extract and its n-hexane, ethyl acetate, butanol and aqueous fraction of Galium aparine L. (Rubiacea) were evaluated in vitro for their antioxidant capacity (DPPH, superoxide radical, phosphomolybdate assay); reducing power (ABTS, hydroxyl, hydrogen peroxide, to reduce Fe(3+) to Fe(2+) ions) and to estimate total flavonoid and phenolic contents. All the free radical generating assay models depicted differential positive scavenging activity but considerable magnitude for all the fractions. The results showed that aqueous fraction strongly scavenge the DPPH, ABTS, hydroxyl, hydrogen peroxide and superoxide radicals. A significantly high correlation coefficient existed between IC(50) values of DPPH and superoxide radical with total phenolic content and phosphomolybdate assay with total flavonoid contents, respectively. These results suggested that aqueous fraction can be a good source of antioxidant therapeutic in oxidative stress damages. SN - 1873-3557 UR - https://www.unboundmedicine.com/medline/citation/23211618/Evaluation_of_diverse_antioxidant_activities_of_Galium_aparine_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1386-1425(12)00927-4 DB - PRIME DP - Unbound Medicine ER -