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Effect of soy isoflavone supplementation on menopausal quality of life.
Menopause. 2013 Apr; 20(4):443-7.M

Abstract

OBJECTIVE

The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women.

METHODS

A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire.

RESULTS

Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups.

CONCLUSIONS

Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.

Authors+Show Affiliations

Oregon Health and Science University, Portland, OR 97239-4501, USA. amatop@ohsu.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

23211877

Citation

Amato, Paula, et al. "Effect of Soy Isoflavone Supplementation On Menopausal Quality of Life." Menopause (New York, N.Y.), vol. 20, no. 4, 2013, pp. 443-7.
Amato P, Young RL, Steinberg FM, et al. Effect of soy isoflavone supplementation on menopausal quality of life. Menopause. 2013;20(4):443-7.
Amato, P., Young, R. L., Steinberg, F. M., Murray, M. J., Lewis, R. D., Cramer, M. A., Barnes, S., Ellis, K. J., Shypailo, R. J., Fraley, J. K., Konzelmann, K. L., Fischer, J. G., LaSalle, C., Smith, E. O., & Wong, W. W. (2013). Effect of soy isoflavone supplementation on menopausal quality of life. Menopause (New York, N.Y.), 20(4), 443-7. https://doi.org/10.1097/gme.0b013e318275025e
Amato P, et al. Effect of Soy Isoflavone Supplementation On Menopausal Quality of Life. Menopause. 2013;20(4):443-7. PubMed PMID: 23211877.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of soy isoflavone supplementation on menopausal quality of life. AU - Amato,Paula, AU - Young,Ronald L, AU - Steinberg,Francene M, AU - Murray,Michael J, AU - Lewis,Richard D, AU - Cramer,Margaret A, AU - Barnes,Stephen, AU - Ellis,Kenneth J, AU - Shypailo,Roman J, AU - Fraley,Joe Kennard, AU - Konzelmann,Karen L, AU - Fischer,Joan G, AU - LaSalle,Colette, AU - Smith,Elliot O'Brian, AU - Wong,William W, PY - 2012/12/6/entrez PY - 2012/12/6/pubmed PY - 2014/3/7/medline SP - 443 EP - 7 JF - Menopause (New York, N.Y.) JO - Menopause VL - 20 IS - 4 N2 - OBJECTIVE: The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women. METHODS: A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire. RESULTS: Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups. CONCLUSIONS: Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women. SN - 1530-0374 UR - https://www.unboundmedicine.com/medline/citation/23211877/Effect_of_soy_isoflavone_supplementation_on_menopausal_quality_of_life_ L2 - http://dx.doi.org/10.1097/gme.0b013e318275025e DB - PRIME DP - Unbound Medicine ER -