Effect of soy isoflavone supplementation on menopausal quality of life.Menopause. 2013 Apr; 20(4):443-7.M
The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women.
A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire.
Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups.
Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.