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Effectiveness of the influenza vaccination program for the elderly in Taiwan.
Vaccine. 2013 Jan 11; 31(4):632-8.V

Abstract

BACKGROUND AND OBJECTIVES

Since 1998, an influenza vaccination program has been implemented by the Taiwan government targeting people aged ≥65 years. However, the evidence of the effectiveness of this program in preventing influenza, which is based on the nation-wide database, is lacking. This study attempted to estimate the effectiveness of the influenza vaccination program in preventing influenza- and pneumonia-associated outpatient visits and hospitalization in the elderly.

METHODS

Randomly sampled data of 1 million claims from the National Health Insurance Research Database compiled into seven consecutive cohorts were used to perform this analysis. Elderly claimants aged ≥65 years were included in each cohort. To decrease potential bias between vaccinated and unvaccinated subjects, the propensity score method was applied. Logistic regression and zero-inflated negative binominal regression were used to examine the effectiveness of vaccination in preventing influenza- and pneumonia-associated outpatient visits and hospitalization.

RESULTS

A significant decrease in both the risk and frequency of hospitalization was observed in elderly people who received influenza vaccination compared with those who did not. No similar decrease was observed in the risk and frequency of outpatient visits for influenza and pneumonia.

CONCLUSION

Vaccination against influenza reduced hospitalization for influenza and pneumonia in elderly Taiwanese people. These results are meaningful for the promotion of vaccination policy. Annual influenza vaccination of the elderly should be encouraged.

Authors+Show Affiliations

Fourth Division, Centers for Disease Control, Taiwan, ROC. s8911512@gmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23212027

Citation

Chiu, Po-Ju, et al. "Effectiveness of the Influenza Vaccination Program for the Elderly in Taiwan." Vaccine, vol. 31, no. 4, 2013, pp. 632-8.
Chiu PJ, Chen CH, Chih YC. Effectiveness of the influenza vaccination program for the elderly in Taiwan. Vaccine. 2013;31(4):632-8.
Chiu, P. J., Chen, C. H., & Chih, Y. C. (2013). Effectiveness of the influenza vaccination program for the elderly in Taiwan. Vaccine, 31(4), 632-8. https://doi.org/10.1016/j.vaccine.2012.11.055
Chiu PJ, Chen CH, Chih YC. Effectiveness of the Influenza Vaccination Program for the Elderly in Taiwan. Vaccine. 2013 Jan 11;31(4):632-8. PubMed PMID: 23212027.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effectiveness of the influenza vaccination program for the elderly in Taiwan. AU - Chiu,Po-Ju, AU - Chen,Chang-Hsun, AU - Chih,Yi-Chien, Y1 - 2012/12/01/ PY - 2012/08/28/received PY - 2012/11/12/revised PY - 2012/11/18/accepted PY - 2012/12/6/entrez PY - 2012/12/6/pubmed PY - 2013/7/13/medline SP - 632 EP - 8 JF - Vaccine JO - Vaccine VL - 31 IS - 4 N2 - BACKGROUND AND OBJECTIVES: Since 1998, an influenza vaccination program has been implemented by the Taiwan government targeting people aged ≥65 years. However, the evidence of the effectiveness of this program in preventing influenza, which is based on the nation-wide database, is lacking. This study attempted to estimate the effectiveness of the influenza vaccination program in preventing influenza- and pneumonia-associated outpatient visits and hospitalization in the elderly. METHODS: Randomly sampled data of 1 million claims from the National Health Insurance Research Database compiled into seven consecutive cohorts were used to perform this analysis. Elderly claimants aged ≥65 years were included in each cohort. To decrease potential bias between vaccinated and unvaccinated subjects, the propensity score method was applied. Logistic regression and zero-inflated negative binominal regression were used to examine the effectiveness of vaccination in preventing influenza- and pneumonia-associated outpatient visits and hospitalization. RESULTS: A significant decrease in both the risk and frequency of hospitalization was observed in elderly people who received influenza vaccination compared with those who did not. No similar decrease was observed in the risk and frequency of outpatient visits for influenza and pneumonia. CONCLUSION: Vaccination against influenza reduced hospitalization for influenza and pneumonia in elderly Taiwanese people. These results are meaningful for the promotion of vaccination policy. Annual influenza vaccination of the elderly should be encouraged. SN - 1873-2518 UR - https://www.unboundmedicine.com/medline/citation/23212027/Effectiveness_of_the_influenza_vaccination_program_for_the_elderly_in_Taiwan_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(12)01681-7 DB - PRIME DP - Unbound Medicine ER -