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Necrobiotic xanthogranuloma as an unusual cause of refractive chronic bilateral leg ulceration.

Abstract

Necrobiotic xanthogranuloma is a progressive histiocytic granulomatous disease with frequent extracutaneous involvement. We have documented an unusual case of necrobiotic xanthogranuloma in a 58-year-old man with a history of recalcitrant and chronic arm and leg ulcerations in the absence of characteristic periorbital involvement. Our patient demonstrates a therapeutic challenge and may display a new necrobiotic inflammatory disorder not previously characterized.

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  • Authors+Show Affiliations

    ,

    University of Toronto, Toronto, Ontario, Canada. nazli.ghiasi@utoronto.ca

    , , ,

    Source

    MeSH

    Adrenal Cortex Hormones
    Biopsy, Needle
    Chronic Disease
    Drug Therapy, Combination
    Follow-Up Studies
    Humans
    Immunohistochemistry
    Leg Ulcer
    Male
    Middle Aged
    Necrobiotic Xanthogranuloma
    Rare Diseases
    Risk Assessment
    Severity of Illness Index

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    23222162

    Citation

    Ghiasi, Nazli, et al. "Necrobiotic Xanthogranuloma as an Unusual Cause of Refractive Chronic Bilateral Leg Ulceration." The International Journal of Lower Extremity Wounds, vol. 11, no. 4, 2012, pp. 293-5.
    Ghiasi N, Alavi A, Coutts PM, et al. Necrobiotic xanthogranuloma as an unusual cause of refractive chronic bilateral leg ulceration. Int J Low Extrem Wounds. 2012;11(4):293-5.
    Ghiasi, N., Alavi, A., Coutts, P. M., Ghazarian, D., & Sibbald, R. G. (2012). Necrobiotic xanthogranuloma as an unusual cause of refractive chronic bilateral leg ulceration. The International Journal of Lower Extremity Wounds, 11(4), pp. 293-5. doi:10.1177/1534734612465434.
    Ghiasi N, et al. Necrobiotic Xanthogranuloma as an Unusual Cause of Refractive Chronic Bilateral Leg Ulceration. Int J Low Extrem Wounds. 2012;11(4):293-5. PubMed PMID: 23222162.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Necrobiotic xanthogranuloma as an unusual cause of refractive chronic bilateral leg ulceration. AU - Ghiasi,Nazli, AU - Alavi,Afsaneh, AU - Coutts,Patricia M, AU - Ghazarian,Danny, AU - Sibbald,R Gary, PY - 2012/12/11/entrez PY - 2012/12/12/pubmed PY - 2013/6/5/medline SP - 293 EP - 5 JF - The international journal of lower extremity wounds JO - Int J Low Extrem Wounds VL - 11 IS - 4 N2 - Necrobiotic xanthogranuloma is a progressive histiocytic granulomatous disease with frequent extracutaneous involvement. We have documented an unusual case of necrobiotic xanthogranuloma in a 58-year-old man with a history of recalcitrant and chronic arm and leg ulcerations in the absence of characteristic periorbital involvement. Our patient demonstrates a therapeutic challenge and may display a new necrobiotic inflammatory disorder not previously characterized. SN - 1552-6941 UR - https://www.unboundmedicine.com/medline/citation/23222162/Necrobiotic_xanthogranuloma_as_an_unusual_cause_of_refractive_chronic_bilateral_leg_ulceration_ L2 - http://journals.sagepub.com/doi/full/10.1177/1534734612465434?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -