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Comfrey root: from tradition to modern clinical trials.

Abstract

Comfrey (Symphytum officinale L.) has been used over many centuries as a medicinal plant. In particular, the use of the root has a longstanding tradition. Today, several randomised controlled trials have demonstrated the efficacy and safety. Comfrey root extract has been used for the topical treatment of painful muscle and joint complaints. It is clinically proven to relieve pain, inflammation and swelling of muscles and joints in the case of degenerative arthritis, acute myalgia in the back, sprains, contusions and strains after sports injuries and accidents, also in children aged 3 years and older. This paper provides information on clinical trials, non-interventional studies and further literature published on comfrey root till date.

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  • Authors+Show Affiliations

    Merck Selbstmedikation GmbH, Röβlerstr. 96, 64293 Darmstadt, Germany. christiane.staiger@merckgroup.com

    Source

    MeSH

    Adult
    Anti-Inflammatory Agents
    Back Pain
    Child
    Child, Preschool
    Comfrey
    Diclofenac
    Drug Combinations
    Humans
    Medicine, Traditional
    Nicotinic Acids
    Osteoarthritis
    Phytotherapy
    Plant Extracts
    Plant Roots
    Product Surveillance, Postmarketing
    Randomized Controlled Trials as Topic
    Rheumatic Diseases
    Skin Cream
    Wounds, Nonpenetrating

    Pub Type(s)

    Comparative Study
    Journal Article
    Review

    Language

    eng

    PubMed ID

    23224633

    Citation

    Staiger, Christiane. "Comfrey Root: From Tradition to Modern Clinical Trials." Wiener Medizinische Wochenschrift (1946), vol. 163, no. 3-4, 2013, pp. 58-64.
    Staiger C. Comfrey root: from tradition to modern clinical trials. Wien Med Wochenschr. 2013;163(3-4):58-64.
    Staiger, C. (2013). Comfrey root: from tradition to modern clinical trials. Wiener Medizinische Wochenschrift (1946), 163(3-4), pp. 58-64. doi:10.1007/s10354-012-0162-4.
    Staiger C. Comfrey Root: From Tradition to Modern Clinical Trials. Wien Med Wochenschr. 2013;163(3-4):58-64. PubMed PMID: 23224633.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Comfrey root: from tradition to modern clinical trials. A1 - Staiger,Christiane, Y1 - 2012/12/07/ PY - 2012/09/05/received PY - 2012/10/25/accepted PY - 2012/12/11/entrez PY - 2012/12/12/pubmed PY - 2013/9/24/medline SP - 58 EP - 64 JF - Wiener medizinische Wochenschrift (1946) JO - Wien Med Wochenschr VL - 163 IS - 3-4 N2 - Comfrey (Symphytum officinale L.) has been used over many centuries as a medicinal plant. In particular, the use of the root has a longstanding tradition. Today, several randomised controlled trials have demonstrated the efficacy and safety. Comfrey root extract has been used for the topical treatment of painful muscle and joint complaints. It is clinically proven to relieve pain, inflammation and swelling of muscles and joints in the case of degenerative arthritis, acute myalgia in the back, sprains, contusions and strains after sports injuries and accidents, also in children aged 3 years and older. This paper provides information on clinical trials, non-interventional studies and further literature published on comfrey root till date. SN - 1563-258X UR - https://www.unboundmedicine.com/medline/citation/23224633/full_citation L2 - https://dx.doi.org/10.1007/s10354-012-0162-4 DB - PRIME DP - Unbound Medicine ER -