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A meta-analysis of coffee and tea consumption and the risk of glioma in adults.

Abstract

BACKGROUND

Coffee contains many compounds, including antioxidants, which could prevent cancerogenesis, and coffee has been related with lower incidence of cancer at several sites. Tea is also rich in antioxidants, mainly polyphenols. To provide a quantitative overall estimate on the relation between coffee and tea consumption and glioma, we combined all published data, using a meta-analytic approach.

METHODS

In September 2012, a bibliography search was carried out in both PubMed and Embase to identify observational studies providing quantitative estimates on the issue. Pooled estimates of the relative risks (RR) and the corresponding 95 % confidence intervals (CI) were calculated using random-effects models.

RESULTS

Six studies (four cohort and two case-control studies) were available for meta-analysis, for a total of about 2100 cases. The summary RRs and 95 % CIs of glioma for drinkers versus non/occasional drinkers were 0.96 (95 % CI: 0.81-1.13) for coffee and 0.86 (95 % CI: 0.78-0.94) for tea, with no heterogeneity between studies. When we compared the highest versus the lowest categories of consumption, the RRs were 1.01 (95 % CI: 0.83-1.22) for coffee, 0.88 (95 % CI: 0.69-1.12) for tea, and 0.75 (95 % CI: 0.54-1.05) for coffee plus tea.

CONCLUSIONS

This meta-analysis, although based on few studies, suggests a lack of association between coffee intake and glioma risk, and a tendency, if any, to a lower risk for tea and coffee plus tea drinkers.

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  • Authors+Show Affiliations

    ,

    Department of Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Via Giuseppe La Masa 19, 0157, Milan, Italy.

    , , , , ,

    Source

    Cancer causes & control : CCC 24:2 2013 Feb pg 267-76

    MeSH

    Adult
    Brain Neoplasms
    Coffee
    Glioma
    Humans
    Risk Factors
    Tea

    Pub Type(s)

    Journal Article
    Meta-Analysis
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    23247638

    Citation

    Malerba, Stefano, et al. "A Meta-analysis of Coffee and Tea Consumption and the Risk of Glioma in Adults." Cancer Causes & Control : CCC, vol. 24, no. 2, 2013, pp. 267-76.
    Malerba S, Galeone C, Pelucchi C, et al. A meta-analysis of coffee and tea consumption and the risk of glioma in adults. Cancer Causes Control. 2013;24(2):267-76.
    Malerba, S., Galeone, C., Pelucchi, C., Turati, F., Hashibe, M., La Vecchia, C., & Tavani, A. (2013). A meta-analysis of coffee and tea consumption and the risk of glioma in adults. Cancer Causes & Control : CCC, 24(2), pp. 267-76. doi:10.1007/s10552-012-0126-4.
    Malerba S, et al. A Meta-analysis of Coffee and Tea Consumption and the Risk of Glioma in Adults. Cancer Causes Control. 2013;24(2):267-76. PubMed PMID: 23247638.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - A meta-analysis of coffee and tea consumption and the risk of glioma in adults. AU - Malerba,Stefano, AU - Galeone,Carlotta, AU - Pelucchi,Claudio, AU - Turati,Federica, AU - Hashibe,Mia, AU - La Vecchia,Carlo, AU - Tavani,Alessandra, Y1 - 2012/12/18/ PY - 2012/10/03/received PY - 2012/12/07/accepted PY - 2012/12/19/entrez PY - 2012/12/19/pubmed PY - 2013/10/31/medline SP - 267 EP - 76 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 24 IS - 2 N2 - BACKGROUND: Coffee contains many compounds, including antioxidants, which could prevent cancerogenesis, and coffee has been related with lower incidence of cancer at several sites. Tea is also rich in antioxidants, mainly polyphenols. To provide a quantitative overall estimate on the relation between coffee and tea consumption and glioma, we combined all published data, using a meta-analytic approach. METHODS: In September 2012, a bibliography search was carried out in both PubMed and Embase to identify observational studies providing quantitative estimates on the issue. Pooled estimates of the relative risks (RR) and the corresponding 95 % confidence intervals (CI) were calculated using random-effects models. RESULTS: Six studies (four cohort and two case-control studies) were available for meta-analysis, for a total of about 2100 cases. The summary RRs and 95 % CIs of glioma for drinkers versus non/occasional drinkers were 0.96 (95 % CI: 0.81-1.13) for coffee and 0.86 (95 % CI: 0.78-0.94) for tea, with no heterogeneity between studies. When we compared the highest versus the lowest categories of consumption, the RRs were 1.01 (95 % CI: 0.83-1.22) for coffee, 0.88 (95 % CI: 0.69-1.12) for tea, and 0.75 (95 % CI: 0.54-1.05) for coffee plus tea. CONCLUSIONS: This meta-analysis, although based on few studies, suggests a lack of association between coffee intake and glioma risk, and a tendency, if any, to a lower risk for tea and coffee plus tea drinkers. SN - 1573-7225 UR - https://www.unboundmedicine.com/medline/citation/23247638/A_meta_analysis_of_coffee_and_tea_consumption_and_the_risk_of_glioma_in_adults_ L2 - https://doi.org/10.1007/s10552-012-0126-4 DB - PRIME DP - Unbound Medicine ER -