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Suppressive effect of the hot-water extract of Ficus pseudopalma Blanco leaves on the postprandial increase in blood glucose level in mice.

Abstract

The use of medicinal plants with anti-diabetic properties continues because of the high cost of diabetes mellitus treatment. In the Bicol region of the Philippines, one local source is the leaves of Ficus pseudopalma Blanco (Philippine fig), which is utilized as an ingredient of their cuisine, and the decoction of its leaves is believed to have a blood-glucose lowering effect. The aim of this study was to evaluate the blood-glucose lowering effect of F. pseudoplama using sugar/carbohydrate-loaded and normoglycemic mice. The results showed that the hot-water extract of the leaves significantly suppressed the increase of blood glucose levels after glucose, maltose and starch loading. On the other hand, the extract did not show any hypoglycemic activity in either fasted or non-fasted mice as compared to the positive control drugs. These results suggest that F. pseudopalma is potentially useful for the management of blood glucose levels in the postprandial condition, as believed in the Bicol region of the Philippines.

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  • Authors+Show Affiliations

    ,

    Graduate School of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya, 468-8503, Japan.

    , , , , ,

    Source

    Journal of natural medicines 67:4 2013 Oct pg 725-9

    MeSH

    Animals
    Blood Glucose
    Female
    Ficus
    Hot Temperature
    Hypoglycemic Agents
    Mice
    Mice, Inbred ICR
    Plant Extracts
    Plant Leaves
    Plants, Medicinal
    Postprandial Period
    Water

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    23263832