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Comparison of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo--a randomized bilateral comparison study.
Photodermatol Photoimmunol Photomed. 2013 Feb; 29(1):27-33.PP

Abstract

BACKGROUND

Vitiligo is an acquired pigment disorder characterized by areas of depigmented skin resulting from the loss of epidermal melanocytes. Recently, several investigations have documented the benefits of excimer phototherapy (e.g., using the 308-nm excimer laser or the 308-nm excimer lamp) for the treatment of vitiligo.

AIM

To compare the effectiveness of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo patients.

METHODS

This intervention study was designed as a randomized self-control trial. Fourteen subjects with 48 symmetrical vitiligo lesions were enrolled in this study. One lesion was treated with the 308-nm excimer laser, and its counterpart was treated with the 308-nm excimer lamp. Lesions were treated three times a week with the same dose on both sides for a total of 20 sessions.

RESULTS

All of the patients completed the study, and 48 lesions were treated. The two treatments exhibited similar results in terms of repigmentation.

CONCLUSIONS

The 308-nm excimer lamp and the 308-nm excimer laser exhibited similar efficacies in treating vitiligo.

Authors+Show Affiliations

Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

23281694

Citation

Shi, Qiong, et al. "Comparison of the 308-nm Excimer Laser With the 308-nm Excimer Lamp in the Treatment of Vitiligo--a Randomized Bilateral Comparison Study." Photodermatology, Photoimmunology & Photomedicine, vol. 29, no. 1, 2013, pp. 27-33.
Shi Q, Li K, Fu J, et al. Comparison of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo--a randomized bilateral comparison study. Photodermatol Photoimmunol Photomed. 2013;29(1):27-33.
Shi, Q., Li, K., Fu, J., Wang, Y., Ma, C., Li, Q., Li, C., & Gao, T. (2013). Comparison of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo--a randomized bilateral comparison study. Photodermatology, Photoimmunology & Photomedicine, 29(1), 27-33. https://doi.org/10.1111/phpp.12015
Shi Q, et al. Comparison of the 308-nm Excimer Laser With the 308-nm Excimer Lamp in the Treatment of Vitiligo--a Randomized Bilateral Comparison Study. Photodermatol Photoimmunol Photomed. 2013;29(1):27-33. PubMed PMID: 23281694.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo--a randomized bilateral comparison study. AU - Shi,Qiong, AU - Li,Kai, AU - Fu,Jun, AU - Wang,Yanchun, AU - Ma,Cuiling, AU - Li,Qiang, AU - Li,Chunying, AU - Gao,Tianwen, PY - 2012/10/03/accepted PY - 2013/1/4/entrez PY - 2013/1/4/pubmed PY - 2013/6/8/medline SP - 27 EP - 33 JF - Photodermatology, photoimmunology & photomedicine JO - Photodermatol Photoimmunol Photomed VL - 29 IS - 1 N2 - BACKGROUND: Vitiligo is an acquired pigment disorder characterized by areas of depigmented skin resulting from the loss of epidermal melanocytes. Recently, several investigations have documented the benefits of excimer phototherapy (e.g., using the 308-nm excimer laser or the 308-nm excimer lamp) for the treatment of vitiligo. AIM: To compare the effectiveness of the 308-nm excimer laser with the 308-nm excimer lamp in the treatment of vitiligo patients. METHODS: This intervention study was designed as a randomized self-control trial. Fourteen subjects with 48 symmetrical vitiligo lesions were enrolled in this study. One lesion was treated with the 308-nm excimer laser, and its counterpart was treated with the 308-nm excimer lamp. Lesions were treated three times a week with the same dose on both sides for a total of 20 sessions. RESULTS: All of the patients completed the study, and 48 lesions were treated. The two treatments exhibited similar results in terms of repigmentation. CONCLUSIONS: The 308-nm excimer lamp and the 308-nm excimer laser exhibited similar efficacies in treating vitiligo. SN - 1600-0781 UR - https://www.unboundmedicine.com/medline/citation/23281694/Comparison_of_the_308_nm_excimer_laser_with_the_308_nm_excimer_lamp_in_the_treatment_of_vitiligo__a_randomized_bilateral_comparison_study_ L2 - https://doi.org/10.1111/phpp.12015 DB - PRIME DP - Unbound Medicine ER -