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Magnesium homeostasis and hypomagnesemia in children with malignancy.
Pediatr Blood Cancer. 2013 May; 60(5):734-40.PB

Abstract

Hypomagnesemia is not uncommon among children with malignancies. It is especially seen in association with certain medications and can be further complicated by the presence of diarrhea and malnutrition. Severe hypomagnesemia may cause disturbances in the neuromuscular and cardiovascular systems. All patients with hypomagnesemia should be supplemented with the mineral, and urgent treatment is indicated when serum magnesium decreases below 1.0 mg/dl, a level under which symptoms may develop. This review addresses the essentials of magnesium physiology, and pathophysiology of hypomagnesemia, its etiologies, clinical manifestations and ways to treat it, with an emphasis on the child with hematologic/oncologic disorders.

Authors+Show Affiliations

Department of Pediatric Hematology-Oncology, The Edmond and Lily Safra Children's Hospital, The Chaim Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23303583

Citation

Kaplinsky, Chaim, and Uri S. Alon. "Magnesium Homeostasis and Hypomagnesemia in Children With Malignancy." Pediatric Blood & Cancer, vol. 60, no. 5, 2013, pp. 734-40.
Kaplinsky C, Alon US. Magnesium homeostasis and hypomagnesemia in children with malignancy. Pediatr Blood Cancer. 2013;60(5):734-40.
Kaplinsky, C., & Alon, U. S. (2013). Magnesium homeostasis and hypomagnesemia in children with malignancy. Pediatric Blood & Cancer, 60(5), 734-40. https://doi.org/10.1002/pbc.24460
Kaplinsky C, Alon US. Magnesium Homeostasis and Hypomagnesemia in Children With Malignancy. Pediatr Blood Cancer. 2013;60(5):734-40. PubMed PMID: 23303583.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Magnesium homeostasis and hypomagnesemia in children with malignancy. AU - Kaplinsky,Chaim, AU - Alon,Uri S, Y1 - 2013/01/09/ PY - 2012/10/16/received PY - 2012/12/05/accepted PY - 2013/1/11/entrez PY - 2013/1/11/pubmed PY - 2013/5/23/medline SP - 734 EP - 40 JF - Pediatric blood & cancer JO - Pediatr Blood Cancer VL - 60 IS - 5 N2 - Hypomagnesemia is not uncommon among children with malignancies. It is especially seen in association with certain medications and can be further complicated by the presence of diarrhea and malnutrition. Severe hypomagnesemia may cause disturbances in the neuromuscular and cardiovascular systems. All patients with hypomagnesemia should be supplemented with the mineral, and urgent treatment is indicated when serum magnesium decreases below 1.0 mg/dl, a level under which symptoms may develop. This review addresses the essentials of magnesium physiology, and pathophysiology of hypomagnesemia, its etiologies, clinical manifestations and ways to treat it, with an emphasis on the child with hematologic/oncologic disorders. SN - 1545-5017 UR - https://www.unboundmedicine.com/medline/citation/23303583/Magnesium_homeostasis_and_hypomagnesemia_in_children_with_malignancy_ L2 - https://doi.org/10.1002/pbc.24460 DB - PRIME DP - Unbound Medicine ER -