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The effects of low-level prenatal lead exposure on birth outcomes.
Environ Pollut. 2013 Apr; 175:30-4.EP

Abstract

Exposure to lead early in life may be a risk factor for fetal growth, but little is known about the effects of low-level prenatal lead exposure on birth outcomes. We measured maternal and cord blood lead levels and examined their associations with birth outcomes. Mother-infant pairs (n = 252) were recruited from a rural area located on the south coast of Laizhou Bay between 2010 and 2011. The median levels of maternal and cord blood lead were 3.20 and 2.52 μg/dL, respectively. Increasing maternal blood lead exposure was associated with decreasing birth weight (β = -148.99; 95% CI, -286.33 to -11.66), and a significant negative relationship was found between cord blood lead levels and birth length (β = -0.84; 95% CI, -1.52 to -0.16). Low-level prenatal lead exposure may adversely affect fetal growth. These results may be important for public health and have implications regarding the recommended blood lead levels.

Authors+Show Affiliations

Department of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23321271

Citation

Xie, Xin, et al. "The Effects of Low-level Prenatal Lead Exposure On Birth Outcomes." Environmental Pollution (Barking, Essex : 1987), vol. 175, 2013, pp. 30-4.
Xie X, Ding G, Cui C, et al. The effects of low-level prenatal lead exposure on birth outcomes. Environ Pollut. 2013;175:30-4.
Xie, X., Ding, G., Cui, C., Chen, L., Gao, Y., Zhou, Y., Shi, R., & Tian, Y. (2013). The effects of low-level prenatal lead exposure on birth outcomes. Environmental Pollution (Barking, Essex : 1987), 175, 30-4. https://doi.org/10.1016/j.envpol.2012.12.013
Xie X, et al. The Effects of Low-level Prenatal Lead Exposure On Birth Outcomes. Environ Pollut. 2013;175:30-4. PubMed PMID: 23321271.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effects of low-level prenatal lead exposure on birth outcomes. AU - Xie,Xin, AU - Ding,Guodong, AU - Cui,Chang, AU - Chen,Limei, AU - Gao,Yu, AU - Zhou,Yijun, AU - Shi,Rong, AU - Tian,Ying, Y1 - 2013/01/12/ PY - 2012/08/26/received PY - 2012/12/10/revised PY - 2012/12/14/accepted PY - 2013/1/17/entrez PY - 2013/1/17/pubmed PY - 2013/4/5/medline SP - 30 EP - 4 JF - Environmental pollution (Barking, Essex : 1987) JO - Environ Pollut VL - 175 N2 - Exposure to lead early in life may be a risk factor for fetal growth, but little is known about the effects of low-level prenatal lead exposure on birth outcomes. We measured maternal and cord blood lead levels and examined their associations with birth outcomes. Mother-infant pairs (n = 252) were recruited from a rural area located on the south coast of Laizhou Bay between 2010 and 2011. The median levels of maternal and cord blood lead were 3.20 and 2.52 μg/dL, respectively. Increasing maternal blood lead exposure was associated with decreasing birth weight (β = -148.99; 95% CI, -286.33 to -11.66), and a significant negative relationship was found between cord blood lead levels and birth length (β = -0.84; 95% CI, -1.52 to -0.16). Low-level prenatal lead exposure may adversely affect fetal growth. These results may be important for public health and have implications regarding the recommended blood lead levels. SN - 1873-6424 UR - https://www.unboundmedicine.com/medline/citation/23321271/The_effects_of_low_level_prenatal_lead_exposure_on_birth_outcomes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0269-7491(12)00538-6 DB - PRIME DP - Unbound Medicine ER -