TY - JOUR T1 - Acute and potentially life-threatening tropical diseases in western travelers--a GeoSentinel multicenter study, 1996-2011. AU - Jensenius,Mogens, AU - Han,Pauline V, AU - Schlagenhauf,Patricia, AU - Schwartz,Eli, AU - Parola,Philippe, AU - Castelli,Francesco, AU - von Sonnenburg,Frank, AU - Loutan,Louis, AU - Leder,Karin, AU - Freedman,David O, AU - ,, Y1 - 2013/01/16/ PY - 2013/1/18/entrez PY - 2013/1/18/pubmed PY - 2013/4/2/medline SP - 397 EP - 404 JF - The American journal of tropical medicine and hygiene JO - Am J Trop Med Hyg VL - 88 IS - 2 N2 - We performed a descriptive analysis of acute and potentially life-threatening tropical diseases among 82,825 ill western travelers reported to GeoSentinel from June of 1996 to August of 2011. We identified 3,655 patients (4.4%) with a total of 3,666 diagnoses representing 13 diseases, including falciparum malaria (76.9%), enteric fever (18.1%), and leptospirosis (2.4%). Ninety-one percent of the patients had fever; the median time from travel to presentation was 16 days. Thirteen (0.4%) patients died: 10 with falciparum malaria, 2 with melioidosis, and 1 with severe dengue. Falciparum malaria was mainly acquired in West Africa, and enteric fever was largely contracted on the Indian subcontinent; leptospirosis, scrub typhus, and murine typhus were principally acquired in Southeast Asia. Western physicians seeing febrile and recently returned travelers from the tropics need to consider a wide profile of potentially life-threatening tropical illnesses, with a specific focus on the most likely diseases described in our large case series. SN - 1476-1645 UR - https://www.unboundmedicine.com/medline/citation/23324216/full_citation L2 - https://ajtmh.org/doi/10.4269/ajtmh.12-0551 DB - PRIME DP - Unbound Medicine ER -