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Prevalence and sex difference of lumbar disc space narrowing in elderly chinese men and women: osteoporotic fractures in men (Hong Kong) and osteoporotic fractures in women (Hong Kong) studies.
Arthritis Rheum. 2013 Apr; 65(4):1004-10.AR

Abstract

OBJECTIVE

Osteoporotic Fractures in Men (Hong Kong) and Osteoporotic Fractures in Women (Hong Kong) represent the first large-scale prospective population-based studies on bone health in elderly (age≥65 years) Chinese men (n=2,000) and women (n=2,000). We undertook the current study to investigate the prevalence of lumbar disc space narrowing in these subjects, and to identify the potential relationship between disc space narrowing and sex, bone mineral density (BMD), and other demographic and clinical data.

METHODS

On lumbar lateral radiographs, L1/L2-L4/L5 disc space was classified into 4 categories: 0=normal; 1=mild narrowing; 2=moderate narrowing; 3=severe narrowing. We compared demographic and clinical data between subjects with and those without total disc space narrowing scores≥3.

RESULTS

Disc space narrowing was more common in elderly women than in elderly men. The mean±SD disc space narrowing score for the 4 discs was 2.71±2.21 for men and 3.08±2.50 for women (P<0.0001). For the 3 age groups of 65-69 years, 70-79 years, and ≥80 years, the average disc space narrowing score increased with increasing age in both men and women, and to a greater degree in women than in men. The average disc space narrowing score differences between women and men were 0.12, 0.40, and 0.90, respectively, in the 3 age groups. For both men and women, a disc space narrowing score≥3 was associated with older age, higher spine and hip BMD, low back pain, and restricted leg mobility.

CONCLUSION

The prevalence and severity of disc space narrowing are higher in elderly women than in elderly men. With increasing age, disc space narrowing progresses at a greater rate in women than in men. A disc space narrowing score≥3 is associated with higher spine and hip BMD.

Authors+Show Affiliations

Department of Imaging and Interventional Radiology, Chinese University of Hong Kong and Prince of Wales Hospital, Shatin, Hong Kong, China. yixiang_wang@cuhk.edu.hkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23335175

Citation

Wang, Yi-Xiang J., et al. "Prevalence and Sex Difference of Lumbar Disc Space Narrowing in Elderly Chinese Men and Women: Osteoporotic Fractures in Men (Hong Kong) and Osteoporotic Fractures in Women (Hong Kong) Studies." Arthritis and Rheumatism, vol. 65, no. 4, 2013, pp. 1004-10.
Wang YX, Griffith JF, Zeng XJ, et al. Prevalence and sex difference of lumbar disc space narrowing in elderly chinese men and women: osteoporotic fractures in men (Hong Kong) and osteoporotic fractures in women (Hong Kong) studies. Arthritis Rheum. 2013;65(4):1004-10.
Wang, Y. X., Griffith, J. F., Zeng, X. J., Deng, M., Kwok, A. W., Leung, J. C., Ahuja, A. T., Kwok, T., & Leung, P. C. (2013). Prevalence and sex difference of lumbar disc space narrowing in elderly chinese men and women: osteoporotic fractures in men (Hong Kong) and osteoporotic fractures in women (Hong Kong) studies. Arthritis and Rheumatism, 65(4), 1004-10. https://doi.org/10.1002/art.37857
Wang YX, et al. Prevalence and Sex Difference of Lumbar Disc Space Narrowing in Elderly Chinese Men and Women: Osteoporotic Fractures in Men (Hong Kong) and Osteoporotic Fractures in Women (Hong Kong) Studies. Arthritis Rheum. 2013;65(4):1004-10. PubMed PMID: 23335175.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and sex difference of lumbar disc space narrowing in elderly chinese men and women: osteoporotic fractures in men (Hong Kong) and osteoporotic fractures in women (Hong Kong) studies. AU - Wang,Yi-Xiang J, AU - Griffith,James F, AU - Zeng,Xian-Jun, AU - Deng,Min, AU - Kwok,Anthony W L, AU - Leung,Jason C S, AU - Ahuja,Anil T, AU - Kwok,Timothy, AU - Leung,Ping Chung, PY - 2012/07/10/received PY - 2013/01/03/accepted PY - 2013/1/22/entrez PY - 2013/1/22/pubmed PY - 2013/5/23/medline SP - 1004 EP - 10 JF - Arthritis and rheumatism JO - Arthritis Rheum VL - 65 IS - 4 N2 - OBJECTIVE: Osteoporotic Fractures in Men (Hong Kong) and Osteoporotic Fractures in Women (Hong Kong) represent the first large-scale prospective population-based studies on bone health in elderly (age≥65 years) Chinese men (n=2,000) and women (n=2,000). We undertook the current study to investigate the prevalence of lumbar disc space narrowing in these subjects, and to identify the potential relationship between disc space narrowing and sex, bone mineral density (BMD), and other demographic and clinical data. METHODS: On lumbar lateral radiographs, L1/L2-L4/L5 disc space was classified into 4 categories: 0=normal; 1=mild narrowing; 2=moderate narrowing; 3=severe narrowing. We compared demographic and clinical data between subjects with and those without total disc space narrowing scores≥3. RESULTS: Disc space narrowing was more common in elderly women than in elderly men. The mean±SD disc space narrowing score for the 4 discs was 2.71±2.21 for men and 3.08±2.50 for women (P<0.0001). For the 3 age groups of 65-69 years, 70-79 years, and ≥80 years, the average disc space narrowing score increased with increasing age in both men and women, and to a greater degree in women than in men. The average disc space narrowing score differences between women and men were 0.12, 0.40, and 0.90, respectively, in the 3 age groups. For both men and women, a disc space narrowing score≥3 was associated with older age, higher spine and hip BMD, low back pain, and restricted leg mobility. CONCLUSION: The prevalence and severity of disc space narrowing are higher in elderly women than in elderly men. With increasing age, disc space narrowing progresses at a greater rate in women than in men. A disc space narrowing score≥3 is associated with higher spine and hip BMD. SN - 1529-0131 UR - https://www.unboundmedicine.com/medline/citation/23335175/Prevalence_and_sex_difference_of_lumbar_disc_space_narrowing_in_elderly_chinese_men_and_women:_osteoporotic_fractures_in_men__Hong_Kong__and_osteoporotic_fractures_in_women__Hong_Kong__studies_ L2 - https://doi.org/10.1002/art.37857 DB - PRIME DP - Unbound Medicine ER -