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Comparison of sonographically guided core needle biopsy and excision in breast papillomas: clinical and sonographic features predictive of malignancy.
J Ultrasound Med. 2013 Feb; 32(2):303-11.JU

Abstract

OBJECTIVES

The aim of this study was to evaluate the clinical factors and sonographic features of benign papillomas of the breast proven by sonographically guided 14-gauge core needle biopsy and their upgrade or malignancy rate after sonographically guided vacuum-assisted excision or surgical excision.

METHODS

We reviewed the medical records of patients who underwent core needle biopsy from July 2005 to December 2011. We evaluated 39 benign papillomas without atypia in 34 patients. The papillomas were diagnosed by core needle biopsy and underwent surgical or vacuum-assisted excision. After core needle biopsy, imaging-histologic correlation was performed to determine concordance. The upgrade and malignancy rates were assessed after surgical or vacuum-assisted excision, and associated clinical and radiologic factors, including patient age, lesion size, distance from the nipple, sonographic features, and American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) category were evaluated.

RESULTS

Three lesions (7.7 %) among 39 papillomas were upgraded to papilloma with atypia after surgical excision. There was no malignancy after excision. The upgrade rates for BI-RADS categories 3, 4a, 4b, and 4c were 0%, 6.9%, 0%, and 20%, respectively. There were no significant differences in the upgrade to papilloma with atypia in terms of the presence of symptoms, lesion size, distance from the nipple, BI-RADS category, or imaging-histologic correlation.

CONCLUSIONS

Prediction of papilloma with atypia, not malignancy, was challenging because there were no associated clinical or radiologic factors to predict papilloma with atypia before excision. However, there was no malignancy after excision. Therefore, intensive surveillance is preferable to immediate surgical excision for benign papillomas diagnosed on core needle biopsy.

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Publisher Full Text

Authors+Show Affiliations

Sohn YM
Department of Radiology, Kyung Hee University Hospital, College of Medicine, Kyung Hee University, Seoul, Korea. sonyumee@naver.com
Park SH
No affiliation info available

MeSH

Biopsy, Large-Core NeedleBreast NeoplasmsFemaleHumansImage-Guided BiopsyNegative-Pressure Wound TherapyPapillomaRetrospective StudiesUltrasonography, Mammary

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23341387

Citation

Sohn, Yu-Mee, and So Hyun Park. "Comparison of Sonographically Guided Core Needle Biopsy and Excision in Breast Papillomas: Clinical and Sonographic Features Predictive of Malignancy." Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine, vol. 32, no. 2, 2013, pp. 303-11.
Sohn YM, Park SH. Comparison of sonographically guided core needle biopsy and excision in breast papillomas: clinical and sonographic features predictive of malignancy. J Ultrasound Med. 2013;32(2):303-11.
Sohn, Y. M., & Park, S. H. (2013). Comparison of sonographically guided core needle biopsy and excision in breast papillomas: clinical and sonographic features predictive of malignancy. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine, 32(2), 303-11.
Sohn YM, Park SH. Comparison of Sonographically Guided Core Needle Biopsy and Excision in Breast Papillomas: Clinical and Sonographic Features Predictive of Malignancy. J Ultrasound Med. 2013;32(2):303-11. PubMed PMID: 23341387.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of sonographically guided core needle biopsy and excision in breast papillomas: clinical and sonographic features predictive of malignancy. AU - Sohn,Yu-Mee, AU - Park,So Hyun, PY - 2013/1/24/entrez PY - 2013/1/24/pubmed PY - 2013/6/19/medline SP - 303 EP - 11 JF - Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine JO - J Ultrasound Med VL - 32 IS - 2 N2 - OBJECTIVES: The aim of this study was to evaluate the clinical factors and sonographic features of benign papillomas of the breast proven by sonographically guided 14-gauge core needle biopsy and their upgrade or malignancy rate after sonographically guided vacuum-assisted excision or surgical excision. METHODS: We reviewed the medical records of patients who underwent core needle biopsy from July 2005 to December 2011. We evaluated 39 benign papillomas without atypia in 34 patients. The papillomas were diagnosed by core needle biopsy and underwent surgical or vacuum-assisted excision. After core needle biopsy, imaging-histologic correlation was performed to determine concordance. The upgrade and malignancy rates were assessed after surgical or vacuum-assisted excision, and associated clinical and radiologic factors, including patient age, lesion size, distance from the nipple, sonographic features, and American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) category were evaluated. RESULTS: Three lesions (7.7 %) among 39 papillomas were upgraded to papilloma with atypia after surgical excision. There was no malignancy after excision. The upgrade rates for BI-RADS categories 3, 4a, 4b, and 4c were 0%, 6.9%, 0%, and 20%, respectively. There were no significant differences in the upgrade to papilloma with atypia in terms of the presence of symptoms, lesion size, distance from the nipple, BI-RADS category, or imaging-histologic correlation. CONCLUSIONS: Prediction of papilloma with atypia, not malignancy, was challenging because there were no associated clinical or radiologic factors to predict papilloma with atypia before excision. However, there was no malignancy after excision. Therefore, intensive surveillance is preferable to immediate surgical excision for benign papillomas diagnosed on core needle biopsy. SN - 1550-9613 UR - https://www.unboundmedicine.com/medline/citation/23341387/Comparison_of_sonographically_guided_core_needle_biopsy_and_excision_in_breast_papillomas:_clinical_and_sonographic_features_predictive_of_malignancy_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0278-4297&date=2013&volume=32&issue=2&spage=303 DB - PRIME DP - Unbound Medicine ER -