Tags

Type your tag names separated by a space and hit enter

Synthesis of quinolones by nickel-catalyzed cycloaddition via elimination of nitrile.
Org Lett. 2013 Feb 15; 15(4):856-9.OL

Abstract

Substituted quinolones were efficiently synthesized via the nickel-catalyzed cycloaddition of o-cyanophenylbenzamide derivatives with alkynes. The reaction involves elimination of a nitrile group by cleavage of the two independent aryl-cyano and aryl-carbonyl C-C bonds of the amides.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Nakai K
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
Kurahashi T
No affiliation info available
Matsubara S
No affiliation info available

MeSH

AlkynesAmidesCatalysisCycloaddition ReactionMolecular StructureNickelNitrilesQuinolones

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23351012

Citation

Nakai, Kenichiro, et al. "Synthesis of Quinolones By Nickel-catalyzed Cycloaddition Via Elimination of Nitrile." Organic Letters, vol. 15, no. 4, 2013, pp. 856-9.
Nakai K, Kurahashi T, Matsubara S. Synthesis of quinolones by nickel-catalyzed cycloaddition via elimination of nitrile. Org Lett. 2013;15(4):856-9.
Nakai, K., Kurahashi, T., & Matsubara, S. (2013). Synthesis of quinolones by nickel-catalyzed cycloaddition via elimination of nitrile. Organic Letters, 15(4), 856-9. https://doi.org/10.1021/ol303546p
Nakai K, Kurahashi T, Matsubara S. Synthesis of Quinolones By Nickel-catalyzed Cycloaddition Via Elimination of Nitrile. Org Lett. 2013 Feb 15;15(4):856-9. PubMed PMID: 23351012.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of quinolones by nickel-catalyzed cycloaddition via elimination of nitrile. AU - Nakai,Kenichiro, AU - Kurahashi,Takuya, AU - Matsubara,Seijiro, Y1 - 2013/01/25/ PY - 2013/1/29/entrez PY - 2013/1/29/pubmed PY - 2013/6/26/medline SP - 856 EP - 9 JF - Organic letters JO - Org Lett VL - 15 IS - 4 N2 - Substituted quinolones were efficiently synthesized via the nickel-catalyzed cycloaddition of o-cyanophenylbenzamide derivatives with alkynes. The reaction involves elimination of a nitrile group by cleavage of the two independent aryl-cyano and aryl-carbonyl C-C bonds of the amides. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/23351012/Synthesis_of_quinolones_by_nickel_catalyzed_cycloaddition_via_elimination_of_nitrile_ L2 - https://doi.org/10.1021/ol303546p DB - PRIME DP - Unbound Medicine ER -