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Prescription opioid mortality trends in New York City, 1990-2006: examining the emergence of an epidemic.
Drug Alcohol Depend. 2013 Sep 01; 132(1-2):53-62.DA

Abstract

BACKGROUND

The drug overdose mortality rate tripled between 1990 and 2006; prescription opioids have driven this epidemic. We examined the period 1990-2006 to inform our understanding of how the current prescription opioid overdose epidemic emerged in urban areas.

METHODS

We used data from the Office of the Chief Medical Examiner to examine changes in demographic and spatial patterns in overdose fatalities induced by prescription opioids (i.e., analgesics and methadone) in New York City (NYC) in 1990-2006, and what factors were associated with death from prescription opioids vs. heroin, historically the most prevalent form of opioid overdose in urban areas.

RESULTS

Analgesic-induced overdose fatalities were the only types of overdose fatalities to increase in 1990-2006 in NYC; the fatality rate increased sevenfold from 0.39 in 1990 to 2.7 per 100,000 persons in 2006. Whites and Latinos were the only racial/ethnic groups to exhibit an increase in overdose-related mortality. Relative to heroin overdose decedents, analgesic and methadone overdose decedents were more likely to be female and to concurrently use psychotherapeutic drugs, but less likely to concurrently use alcohol or cocaine. Analgesic overdose decedents were less likely to be Black or Hispanic, while methadone overdose decedents were more likely to be Black or Hispanic in contrast to heroin overdose decedents.

CONCLUSIONS

The distinct epidemiologic profiles exhibited by analgesic and methadone overdose fatalities highlight the need to define drug-specific public health prevention efforts.

Authors+Show Affiliations

Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY 10032, USA. mc3226@columbia.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

23357743

Citation

Cerdá, Magdalena, et al. "Prescription Opioid Mortality Trends in New York City, 1990-2006: Examining the Emergence of an Epidemic." Drug and Alcohol Dependence, vol. 132, no. 1-2, 2013, pp. 53-62.
Cerdá M, Ransome Y, Keyes KM, et al. Prescription opioid mortality trends in New York City, 1990-2006: examining the emergence of an epidemic. Drug Alcohol Depend. 2013;132(1-2):53-62.
Cerdá, M., Ransome, Y., Keyes, K. M., Koenen, K. C., Tracy, M., Tardiff, K. J., Vlahov, D., & Galea, S. (2013). Prescription opioid mortality trends in New York City, 1990-2006: examining the emergence of an epidemic. Drug and Alcohol Dependence, 132(1-2), 53-62. https://doi.org/10.1016/j.drugalcdep.2012.12.027
Cerdá M, et al. Prescription Opioid Mortality Trends in New York City, 1990-2006: Examining the Emergence of an Epidemic. Drug Alcohol Depend. 2013 Sep 1;132(1-2):53-62. PubMed PMID: 23357743.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prescription opioid mortality trends in New York City, 1990-2006: examining the emergence of an epidemic. AU - Cerdá,Magdalena, AU - Ransome,Yusuf, AU - Keyes,Katherine M, AU - Koenen,Karestan C, AU - Tracy,Melissa, AU - Tardiff,Kenneth J, AU - Vlahov,David, AU - Galea,Sandro, Y1 - 2013/01/26/ PY - 2012/09/26/received PY - 2012/12/29/revised PY - 2012/12/29/accepted PY - 2013/1/30/entrez PY - 2013/1/30/pubmed PY - 2014/3/15/medline KW - Epidemiology KW - Methadone KW - Mortality KW - Opioid analgesics KW - Overdose KW - Prescription drugs KW - Urban health SP - 53 EP - 62 JF - Drug and alcohol dependence JO - Drug Alcohol Depend VL - 132 IS - 1-2 N2 - BACKGROUND: The drug overdose mortality rate tripled between 1990 and 2006; prescription opioids have driven this epidemic. We examined the period 1990-2006 to inform our understanding of how the current prescription opioid overdose epidemic emerged in urban areas. METHODS: We used data from the Office of the Chief Medical Examiner to examine changes in demographic and spatial patterns in overdose fatalities induced by prescription opioids (i.e., analgesics and methadone) in New York City (NYC) in 1990-2006, and what factors were associated with death from prescription opioids vs. heroin, historically the most prevalent form of opioid overdose in urban areas. RESULTS: Analgesic-induced overdose fatalities were the only types of overdose fatalities to increase in 1990-2006 in NYC; the fatality rate increased sevenfold from 0.39 in 1990 to 2.7 per 100,000 persons in 2006. Whites and Latinos were the only racial/ethnic groups to exhibit an increase in overdose-related mortality. Relative to heroin overdose decedents, analgesic and methadone overdose decedents were more likely to be female and to concurrently use psychotherapeutic drugs, but less likely to concurrently use alcohol or cocaine. Analgesic overdose decedents were less likely to be Black or Hispanic, while methadone overdose decedents were more likely to be Black or Hispanic in contrast to heroin overdose decedents. CONCLUSIONS: The distinct epidemiologic profiles exhibited by analgesic and methadone overdose fatalities highlight the need to define drug-specific public health prevention efforts. SN - 1879-0046 UR - https://www.unboundmedicine.com/medline/citation/23357743/Prescription_opioid_mortality_trends_in_New_York_City_1990_2006:_examining_the_emergence_of_an_epidemic_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0376-8716(13)00003-3 DB - PRIME DP - Unbound Medicine ER -