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Premaxillary protrusion assessment by the maxilla-nasion-mandible angle in fetuses with facial clefts.
Prenat Diagn. 2013 Apr; 33(4):354-9.PD

Abstract

OBJECTIVE

The aim of the study was to measure the degree of premaxillary protrusion in fetuses with orofacial clefts of various severities.

METHODS

The maxilla-nasion-mandible (MNM) angle was measured retrospectively on by multiplanar corrected volumes. Sixty-two fetuses with orofacial clefts and known outcome volumes of the fetal head were available.

RESULTS

In 48 of the 62 cases, the MNM angle could be measured [mean gestational age 23 (range, 18-30) weeks]. The mean MNM angle was normal in all nine cases with cleft lip and intact alveolar ridge (15.2°; range, 12.5°- 16.9°). In 24 cases with unilateral cleft lip with or without cleft palate (UCL/P), the mean MNM angle was 20.0° (range, 13.3-26.2°), being above the 95th percentile in 79% (n = 19) and normal in 21% (n = 5). In 14 bilateral cleft lip and palate (BCL/P) cases, the mean MNM angle was 26.5° (range, 19.2°-33.7°) and above the 95th percentile in all cases. There was no difference in MNM angle between isolated clefts and clefts associated with other anomalies. In one case with a Tessier 4 cleft, the MNM angle was above the 95th percentile (25.2°).

CONCLUSION

The premaxilla tends to protrude in both BCL/P as UCL/P cases. The degree of protrusion varies greatly, especially in the BCL/P group.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, St. Antonius Hospital, Nieuwegein, The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23362132

Citation

de Jong-Pleij, E A P., et al. "Premaxillary Protrusion Assessment By the Maxilla-nasion-mandible Angle in Fetuses With Facial Clefts." Prenatal Diagnosis, vol. 33, no. 4, 2013, pp. 354-9.
de Jong-Pleij EA, Pistorius LR, Ribbert LS, et al. Premaxillary protrusion assessment by the maxilla-nasion-mandible angle in fetuses with facial clefts. Prenat Diagn. 2013;33(4):354-9.
de Jong-Pleij, E. A., Pistorius, L. R., Ribbert, L. S., Breugem, C. C., Bakker, M., Tromp, E., & Bilardo, C. M. (2013). Premaxillary protrusion assessment by the maxilla-nasion-mandible angle in fetuses with facial clefts. Prenatal Diagnosis, 33(4), 354-9. https://doi.org/10.1002/pd.4062
de Jong-Pleij EA, et al. Premaxillary Protrusion Assessment By the Maxilla-nasion-mandible Angle in Fetuses With Facial Clefts. Prenat Diagn. 2013;33(4):354-9. PubMed PMID: 23362132.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Premaxillary protrusion assessment by the maxilla-nasion-mandible angle in fetuses with facial clefts. AU - de Jong-Pleij,E A P, AU - Pistorius,L R, AU - Ribbert,L S M, AU - Breugem,C C, AU - Bakker,M, AU - Tromp,E, AU - Bilardo,C M, Y1 - 2013/01/30/ PY - 2013/1/31/entrez PY - 2013/1/31/pubmed PY - 2014/1/11/medline SP - 354 EP - 9 JF - Prenatal diagnosis JO - Prenat Diagn VL - 33 IS - 4 N2 - OBJECTIVE: The aim of the study was to measure the degree of premaxillary protrusion in fetuses with orofacial clefts of various severities. METHODS: The maxilla-nasion-mandible (MNM) angle was measured retrospectively on by multiplanar corrected volumes. Sixty-two fetuses with orofacial clefts and known outcome volumes of the fetal head were available. RESULTS: In 48 of the 62 cases, the MNM angle could be measured [mean gestational age 23 (range, 18-30) weeks]. The mean MNM angle was normal in all nine cases with cleft lip and intact alveolar ridge (15.2°; range, 12.5°- 16.9°). In 24 cases with unilateral cleft lip with or without cleft palate (UCL/P), the mean MNM angle was 20.0° (range, 13.3-26.2°), being above the 95th percentile in 79% (n = 19) and normal in 21% (n = 5). In 14 bilateral cleft lip and palate (BCL/P) cases, the mean MNM angle was 26.5° (range, 19.2°-33.7°) and above the 95th percentile in all cases. There was no difference in MNM angle between isolated clefts and clefts associated with other anomalies. In one case with a Tessier 4 cleft, the MNM angle was above the 95th percentile (25.2°). CONCLUSION: The premaxilla tends to protrude in both BCL/P as UCL/P cases. The degree of protrusion varies greatly, especially in the BCL/P group. SN - 1097-0223 UR - https://www.unboundmedicine.com/medline/citation/23362132/Premaxillary_protrusion_assessment_by_the_maxilla_nasion_mandible_angle_in_fetuses_with_facial_clefts_ L2 - https://doi.org/10.1002/pd.4062 DB - PRIME DP - Unbound Medicine ER -