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Metabolic syndrome risk factors in overweight, obese, and extremely obese Brazilian adolescents.
Nutr J. 2013 Jan 30; 12:19.NJ

Abstract

BACKGROUND

Obesity in infancy and adolescence has acquired epidemic dimensions worldwide and is considered a risk factor for a number of disorders that can manifest at an early age, such as Metabolic Syndrome (MS). In this study, we evaluated overweight, obese, and extremely obese adolescents for the presence of MS, and studied the prevalence of single factors of the syndrome in this population.

METHODS

A total of 321 adolescents (174 females and 147 males) aged 10 to 16 years, attending the Adolescent Outpatient Clinic of Botucatu School of Medicine, Brazil, between April 2009 and April 2011 were enrolled in this study. Adolescents underwent anthropometric evaluation (weight, height, and abdominal circumference) and Body Mass Index (BMI) was estimated according to age and gender, following Disease Control and Prevention Centers recommendations (CDC, 2000). Blood pressure was measured and individuals with BMI ≥ 85th percentile were submitted to laboratory evaluation for Total Cholesterol, HDL and LDL Cholesterol, Triglycerides, Fasting Insulinemia, and Fasting Glycemia to identify MS factors, according to the criteria suggested by the International Diabetes Federation. Insulin resistance was calculated by HOMA-IR, Quicki, and Fasting Glycemia/Fasting Insulinemia (FGI).

RESULTS AND DISCUSSION

Of the 321 adolescents, 95 (29.6%) were overweight, 129 (40.2%) were obese, and 97 (30.2%) were extremely obese. Around 18% were diagnosed with MS. The most prevalent risk factors were abdominal circumference ≥90th percentile (55%), HDL < 40 mg/dL (35.5%), High Pressure ≥130/85 mm/Hg (21%), Triglycerides ≥150 mg/dL (18.5%), and Fasting Glycemia ≥100 mg/dL (2%). Insulin resistance was observed in 65% of the adolescents.

CONCLUSION

An increased prevalence of overweight and obesity, together with cardiometabolic risk factors such as dyslipidemia and abnormal blood pressure, were observed in adolescents, contributing to the onset of metabolic syndrome at younger ages. Risk factors for MS were more prevalent in females.

Authors+Show Affiliations

Department of Pediatrics, Adolescent Medicine Course, Post Graduate Program in Gynecology, Obstetrics, and Mastology, Botucatu School of Medicine, São Paulo State University (UNESP), São Paulo, Brazil. tamara@fmb.unesp.brNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23363783

Citation

Rizzo, Anapaula Cb, et al. "Metabolic Syndrome Risk Factors in Overweight, Obese, and Extremely Obese Brazilian Adolescents." Nutrition Journal, vol. 12, 2013, p. 19.
Rizzo AC, Goldberg TB, Silva CC, et al. Metabolic syndrome risk factors in overweight, obese, and extremely obese Brazilian adolescents. Nutr J. 2013;12:19.
Rizzo, A. C., Goldberg, T. B., Silva, C. C., Kurokawa, C. S., Nunes, H. R., & Corrente, J. E. (2013). Metabolic syndrome risk factors in overweight, obese, and extremely obese Brazilian adolescents. Nutrition Journal, 12, 19. https://doi.org/10.1186/1475-2891-12-19
Rizzo AC, et al. Metabolic Syndrome Risk Factors in Overweight, Obese, and Extremely Obese Brazilian Adolescents. Nutr J. 2013 Jan 30;12:19. PubMed PMID: 23363783.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Metabolic syndrome risk factors in overweight, obese, and extremely obese Brazilian adolescents. AU - Rizzo,Anapaula Cb, AU - Goldberg,Tamara Bl, AU - Silva,Carla C, AU - Kurokawa,Cilmery S, AU - Nunes,Helio Rc, AU - Corrente,José E, Y1 - 2013/01/30/ PY - 2012/09/05/received PY - 2013/01/23/accepted PY - 2013/2/1/entrez PY - 2013/2/1/pubmed PY - 2013/7/13/medline SP - 19 EP - 19 JF - Nutrition journal JO - Nutr J VL - 12 N2 - BACKGROUND: Obesity in infancy and adolescence has acquired epidemic dimensions worldwide and is considered a risk factor for a number of disorders that can manifest at an early age, such as Metabolic Syndrome (MS). In this study, we evaluated overweight, obese, and extremely obese adolescents for the presence of MS, and studied the prevalence of single factors of the syndrome in this population. METHODS: A total of 321 adolescents (174 females and 147 males) aged 10 to 16 years, attending the Adolescent Outpatient Clinic of Botucatu School of Medicine, Brazil, between April 2009 and April 2011 were enrolled in this study. Adolescents underwent anthropometric evaluation (weight, height, and abdominal circumference) and Body Mass Index (BMI) was estimated according to age and gender, following Disease Control and Prevention Centers recommendations (CDC, 2000). Blood pressure was measured and individuals with BMI ≥ 85th percentile were submitted to laboratory evaluation for Total Cholesterol, HDL and LDL Cholesterol, Triglycerides, Fasting Insulinemia, and Fasting Glycemia to identify MS factors, according to the criteria suggested by the International Diabetes Federation. Insulin resistance was calculated by HOMA-IR, Quicki, and Fasting Glycemia/Fasting Insulinemia (FGI). RESULTS AND DISCUSSION: Of the 321 adolescents, 95 (29.6%) were overweight, 129 (40.2%) were obese, and 97 (30.2%) were extremely obese. Around 18% were diagnosed with MS. The most prevalent risk factors were abdominal circumference ≥90th percentile (55%), HDL < 40 mg/dL (35.5%), High Pressure ≥130/85 mm/Hg (21%), Triglycerides ≥150 mg/dL (18.5%), and Fasting Glycemia ≥100 mg/dL (2%). Insulin resistance was observed in 65% of the adolescents. CONCLUSION: An increased prevalence of overweight and obesity, together with cardiometabolic risk factors such as dyslipidemia and abnormal blood pressure, were observed in adolescents, contributing to the onset of metabolic syndrome at younger ages. Risk factors for MS were more prevalent in females. SN - 1475-2891 UR - https://www.unboundmedicine.com/medline/citation/23363783/Metabolic_syndrome_risk_factors_in_overweight_obese_and_extremely_obese_Brazilian_adolescents_ L2 - https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-12-19 DB - PRIME DP - Unbound Medicine ER -