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Isolation, structural elucidation, MS profiling, and evaluation of triglyceride accumulation inhibitory effects of benzophenone C-glucosides from leaves of Mangifera indica L.
J Agric Food Chem. 2013 Feb 27; 61(8):1884-95.JA

Abstract

Seventy percent ethanol-water extract from the leaves of Mangifera indica L. (Anacardiaceae) was found to show an inhibitory effect on triglyceride (TG) accumulation in 3T3-L1 cells. From the active fraction, six new benzophenone C-glucosides, foliamangiferosides A(3) (1), A(4) (2), C(4) (3), C(5) (4), C(6) (5), and C(7) (6) together with 11 known benzophenone C-glucosides (7-17) were obtained. In this paper, isolation, structure elucidation (1-6), and MS fragment cleavage pathways of all 17 isolates were studied. 1-6 showed inhibitory effects on TG and free fatty acid accumulation in 3T3-L1 cells at 10 μM.

Authors+Show Affiliations

Tianjin State Key Laboratory of Modern Chinese Medicine, Nankai District, Tianjin, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23368644

Citation

Zhang, Yi, et al. "Isolation, Structural Elucidation, MS Profiling, and Evaluation of Triglyceride Accumulation Inhibitory Effects of Benzophenone C-glucosides From Leaves of Mangifera Indica L." Journal of Agricultural and Food Chemistry, vol. 61, no. 8, 2013, pp. 1884-95.
Zhang Y, Han L, Ge D, et al. Isolation, structural elucidation, MS profiling, and evaluation of triglyceride accumulation inhibitory effects of benzophenone C-glucosides from leaves of Mangifera indica L. J Agric Food Chem. 2013;61(8):1884-95.
Zhang, Y., Han, L., Ge, D., Liu, X., Liu, E., Wu, C., Gao, X., & Wang, T. (2013). Isolation, structural elucidation, MS profiling, and evaluation of triglyceride accumulation inhibitory effects of benzophenone C-glucosides from leaves of Mangifera indica L. Journal of Agricultural and Food Chemistry, 61(8), 1884-95. https://doi.org/10.1021/jf305256w
Zhang Y, et al. Isolation, Structural Elucidation, MS Profiling, and Evaluation of Triglyceride Accumulation Inhibitory Effects of Benzophenone C-glucosides From Leaves of Mangifera Indica L. J Agric Food Chem. 2013 Feb 27;61(8):1884-95. PubMed PMID: 23368644.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Isolation, structural elucidation, MS profiling, and evaluation of triglyceride accumulation inhibitory effects of benzophenone C-glucosides from leaves of Mangifera indica L. AU - Zhang,Yi, AU - Han,Lifeng, AU - Ge,Dandan, AU - Liu,Xuefeng, AU - Liu,Erwei, AU - Wu,Chunhua, AU - Gao,Xiumei, AU - Wang,Tao, Y1 - 2013/02/18/ PY - 2013/2/2/entrez PY - 2013/2/2/pubmed PY - 2013/12/16/medline SP - 1884 EP - 95 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 61 IS - 8 N2 - Seventy percent ethanol-water extract from the leaves of Mangifera indica L. (Anacardiaceae) was found to show an inhibitory effect on triglyceride (TG) accumulation in 3T3-L1 cells. From the active fraction, six new benzophenone C-glucosides, foliamangiferosides A(3) (1), A(4) (2), C(4) (3), C(5) (4), C(6) (5), and C(7) (6) together with 11 known benzophenone C-glucosides (7-17) were obtained. In this paper, isolation, structure elucidation (1-6), and MS fragment cleavage pathways of all 17 isolates were studied. 1-6 showed inhibitory effects on TG and free fatty acid accumulation in 3T3-L1 cells at 10 μM. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/23368644/Isolation_structural_elucidation_MS_profiling_and_evaluation_of_triglyceride_accumulation_inhibitory_effects_of_benzophenone_C_glucosides_from_leaves_of_Mangifera_indica_L_ L2 - https://doi.org/10.1021/jf305256w DB - PRIME DP - Unbound Medicine ER -