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Isolation, structural elucidation, MS profiling, and evaluation of triglyceride accumulation inhibitory effects of benzophenone C-glucosides from leaves of Mangifera indica L.
J Agric Food Chem. 2013 Feb 27; 61(8):1884-95.JA

Abstract

Seventy percent ethanol-water extract from the leaves of Mangifera indica L. (Anacardiaceae) was found to show an inhibitory effect on triglyceride (TG) accumulation in 3T3-L1 cells. From the active fraction, six new benzophenone C-glucosides, foliamangiferosides A(3) (1), A(4) (2), C(4) (3), C(5) (4), C(6) (5), and C(7) (6) together with 11 known benzophenone C-glucosides (7-17) were obtained. In this paper, isolation, structure elucidation (1-6), and MS fragment cleavage pathways of all 17 isolates were studied. 1-6 showed inhibitory effects on TG and free fatty acid accumulation in 3T3-L1 cells at 10 μM.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Zhang Y
Tianjin State Key Laboratory of Modern Chinese Medicine, Nankai District, Tianjin, China.
Han L
No affiliation info available
Ge D
No affiliation info available
Liu X
No affiliation info available
Liu E
No affiliation info available
Wu C
No affiliation info available
Gao X
No affiliation info available
Wang T
No affiliation info available

MeSH

3T3-L1 CellsAnimalsBenzophenonesDown-RegulationGlucosidesMangiferaMass SpectrometryMiceMolecular StructurePlant ExtractsPlant LeavesTriglycerides

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23368644

Citation

Zhang, Yi, et al. "Isolation, Structural Elucidation, MS Profiling, and Evaluation of Triglyceride Accumulation Inhibitory Effects of Benzophenone C-glucosides From Leaves of Mangifera Indica L." Journal of Agricultural and Food Chemistry, vol. 61, no. 8, 2013, pp. 1884-95.
Zhang Y, Han L, Ge D, et al. Isolation, structural elucidation, MS profiling, and evaluation of triglyceride accumulation inhibitory effects of benzophenone C-glucosides from leaves of Mangifera indica L. J Agric Food Chem. 2013;61(8):1884-95.
Zhang, Y., Han, L., Ge, D., Liu, X., Liu, E., Wu, C., Gao, X., & Wang, T. (2013). Isolation, structural elucidation, MS profiling, and evaluation of triglyceride accumulation inhibitory effects of benzophenone C-glucosides from leaves of Mangifera indica L. Journal of Agricultural and Food Chemistry, 61(8), 1884-95. https://doi.org/10.1021/jf305256w
Zhang Y, et al. Isolation, Structural Elucidation, MS Profiling, and Evaluation of Triglyceride Accumulation Inhibitory Effects of Benzophenone C-glucosides From Leaves of Mangifera Indica L. J Agric Food Chem. 2013 Feb 27;61(8):1884-95. PubMed PMID: 23368644.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Isolation, structural elucidation, MS profiling, and evaluation of triglyceride accumulation inhibitory effects of benzophenone C-glucosides from leaves of Mangifera indica L. AU - Zhang,Yi, AU - Han,Lifeng, AU - Ge,Dandan, AU - Liu,Xuefeng, AU - Liu,Erwei, AU - Wu,Chunhua, AU - Gao,Xiumei, AU - Wang,Tao, Y1 - 2013/02/18/ PY - 2013/2/2/entrez PY - 2013/2/2/pubmed PY - 2013/12/16/medline SP - 1884 EP - 95 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 61 IS - 8 N2 - Seventy percent ethanol-water extract from the leaves of Mangifera indica L. (Anacardiaceae) was found to show an inhibitory effect on triglyceride (TG) accumulation in 3T3-L1 cells. From the active fraction, six new benzophenone C-glucosides, foliamangiferosides A(3) (1), A(4) (2), C(4) (3), C(5) (4), C(6) (5), and C(7) (6) together with 11 known benzophenone C-glucosides (7-17) were obtained. In this paper, isolation, structure elucidation (1-6), and MS fragment cleavage pathways of all 17 isolates were studied. 1-6 showed inhibitory effects on TG and free fatty acid accumulation in 3T3-L1 cells at 10 μM. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/23368644/Isolation_structural_elucidation_MS_profiling_and_evaluation_of_triglyceride_accumulation_inhibitory_effects_of_benzophenone_C_glucosides_from_leaves_of_Mangifera_indica_L_ L2 - https://doi.org/10.1021/jf305256w DB - PRIME DP - Unbound Medicine ER -