Tags

Type your tag names separated by a space and hit enter

Mechanisms of the placebo response.
Pulm Pharmacol Ther. 2013 Oct; 26(5):520-3.PP

Abstract

The concept of placebo response has evolved in the past few years from the clinical trial setting and medical practice to a psychobiological model that gives us important information on how the patient's brain is modified by the psychosocial context around the therapy. In this review, some examples will be given where physiological or pathological conditions are altered following the administration of an inert substance along with verbal instructions tailored to induce expectation of a change, and explanations will be presented with details on neurotransmitter changes and neural pathways activated. Although nothing is known about the biological underpinnings of the placebo response in the respiratory system, this review may help extending the neurobiological investigation of placebos from conditions such as pain and Parkinson's disease to respiratory disorders and symptoms such as cough.

Authors+Show Affiliations

Department of Neuroscience, University of Turin Medical School, Turin, Italy; National Institute of Neuroscience, Turin, Italy. fabrizio.benedetti@unito.itNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

23370213

Citation

Benedetti, Fabrizio, and Martina Amanzio. "Mechanisms of the Placebo Response." Pulmonary Pharmacology & Therapeutics, vol. 26, no. 5, 2013, pp. 520-3.
Benedetti F, Amanzio M. Mechanisms of the placebo response. Pulm Pharmacol Ther. 2013;26(5):520-3.
Benedetti, F., & Amanzio, M. (2013). Mechanisms of the placebo response. Pulmonary Pharmacology & Therapeutics, 26(5), 520-3. https://doi.org/10.1016/j.pupt.2013.01.006
Benedetti F, Amanzio M. Mechanisms of the Placebo Response. Pulm Pharmacol Ther. 2013;26(5):520-3. PubMed PMID: 23370213.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mechanisms of the placebo response. AU - Benedetti,Fabrizio, AU - Amanzio,Martina, Y1 - 2013/01/28/ PY - 2012/12/06/received PY - 2013/01/14/accepted PY - 2013/2/2/entrez PY - 2013/2/2/pubmed PY - 2014/5/6/medline KW - Conditioning KW - Cough KW - Expectation KW - Nocebo KW - Pain KW - Placebo SP - 520 EP - 3 JF - Pulmonary pharmacology & therapeutics JO - Pulm Pharmacol Ther VL - 26 IS - 5 N2 - The concept of placebo response has evolved in the past few years from the clinical trial setting and medical practice to a psychobiological model that gives us important information on how the patient's brain is modified by the psychosocial context around the therapy. In this review, some examples will be given where physiological or pathological conditions are altered following the administration of an inert substance along with verbal instructions tailored to induce expectation of a change, and explanations will be presented with details on neurotransmitter changes and neural pathways activated. Although nothing is known about the biological underpinnings of the placebo response in the respiratory system, this review may help extending the neurobiological investigation of placebos from conditions such as pain and Parkinson's disease to respiratory disorders and symptoms such as cough. SN - 1522-9629 UR - https://www.unboundmedicine.com/medline/citation/23370213/Mechanisms_of_the_placebo_response_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1094-5539(13)00052-7 DB - PRIME DP - Unbound Medicine ER -