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Human ultrasonic hearing is induced by a direct ultrasonic stimulation of the cochlea.
Neurosci Lett. 2013 Feb 28; 539:71-6.NL

Abstract

Ultrasound can be perceived by bone-conduction. The cochlear basal turn is involved in processing bone-conducted ultrasound (BCU) information. Previous studies have suggested that ultrasonic perception is induced by ultrasound itself. In contrast, it has also been suggested that a lower frequency sound is generated in non-linear process during the transmission pathway to the cochlea to induce an auditory sensations. To address this issue, we assessed cisplatin-induced changes in BCU sensitivity at 27, 30 and 33kHz in 20 participants (40 ears) who were scheduled to undergo cisplatin chemoradiation therapy. Following the treatment, 62.5% ears were diagnosed with hearing loss according to the criteria of the American Speech-Language-Hearing Association. As expected, significant increases in sensitivity threshold were observed for air-conducted sounds ranging from 8 to 14kHz. In contrast, the BCU threshold significantly decreased after the treatment. Considering that both air-conducted high-frequency sound and BCU are perceived in the cochlear basal turn, these findings indicate that ultrasonic perception is independent of hearing a lower frequency sound generated in non-linear process. In addition, our findings support the hypothesis that ultrasound itself induces ultrasonic perception in the cochlea. The observed cisplatin-induced increase in BCU sensitivity may be explained by hypersensitivity associated with outer hair cells' disorder.

Authors+Show Affiliations

Department of Otolaryngology-Head and Neck Surgery, Nara Medical University, 840 Shijo-cho, Kashihara Nara 634-8522, Japan. tokayasu@naramed-u.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23384569

Citation

Okayasu, Tadao, et al. "Human Ultrasonic Hearing Is Induced By a Direct Ultrasonic Stimulation of the Cochlea." Neuroscience Letters, vol. 539, 2013, pp. 71-6.
Okayasu T, Nishimura T, Yamashita A, et al. Human ultrasonic hearing is induced by a direct ultrasonic stimulation of the cochlea. Neurosci Lett. 2013;539:71-6.
Okayasu, T., Nishimura, T., Yamashita, A., Saito, O., Fukuda, F., Yanai, S., & Hosoi, H. (2013). Human ultrasonic hearing is induced by a direct ultrasonic stimulation of the cochlea. Neuroscience Letters, 539, 71-6. https://doi.org/10.1016/j.neulet.2013.01.040
Okayasu T, et al. Human Ultrasonic Hearing Is Induced By a Direct Ultrasonic Stimulation of the Cochlea. Neurosci Lett. 2013 Feb 28;539:71-6. PubMed PMID: 23384569.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Human ultrasonic hearing is induced by a direct ultrasonic stimulation of the cochlea. AU - Okayasu,Tadao, AU - Nishimura,Tadashi, AU - Yamashita,Akinori, AU - Saito,Osamu, AU - Fukuda,Fumi, AU - Yanai,Shuichi, AU - Hosoi,Hiroshi, Y1 - 2013/02/04/ PY - 2012/11/22/received PY - 2013/01/18/accepted PY - 2013/2/7/entrez PY - 2013/2/7/pubmed PY - 2013/8/1/medline SP - 71 EP - 6 JF - Neuroscience letters JO - Neurosci Lett VL - 539 N2 - Ultrasound can be perceived by bone-conduction. The cochlear basal turn is involved in processing bone-conducted ultrasound (BCU) information. Previous studies have suggested that ultrasonic perception is induced by ultrasound itself. In contrast, it has also been suggested that a lower frequency sound is generated in non-linear process during the transmission pathway to the cochlea to induce an auditory sensations. To address this issue, we assessed cisplatin-induced changes in BCU sensitivity at 27, 30 and 33kHz in 20 participants (40 ears) who were scheduled to undergo cisplatin chemoradiation therapy. Following the treatment, 62.5% ears were diagnosed with hearing loss according to the criteria of the American Speech-Language-Hearing Association. As expected, significant increases in sensitivity threshold were observed for air-conducted sounds ranging from 8 to 14kHz. In contrast, the BCU threshold significantly decreased after the treatment. Considering that both air-conducted high-frequency sound and BCU are perceived in the cochlear basal turn, these findings indicate that ultrasonic perception is independent of hearing a lower frequency sound generated in non-linear process. In addition, our findings support the hypothesis that ultrasound itself induces ultrasonic perception in the cochlea. The observed cisplatin-induced increase in BCU sensitivity may be explained by hypersensitivity associated with outer hair cells' disorder. SN - 1872-7972 UR - https://www.unboundmedicine.com/medline/citation/23384569/Human_ultrasonic_hearing_is_induced_by_a_direct_ultrasonic_stimulation_of_the_cochlea_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0304-3940(13)00082-7 DB - PRIME DP - Unbound Medicine ER -