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Microencapsulation of menthol by crosslinked chitosan via porous glass membrane emulsification technique and their controlled release properties.
J Microencapsul. 2013; 30(5):498-509.JM

Abstract

Chitosan-encapsulated menthol microcapsules were successfully prepared in an oil-in-water (o/w) emulsion using the Shirasu Porous Glass (SPG) membrane emulsification technique and high-speed dispersion technique for preparing a mixed o/w emulsion. The size of the menthol-loaded chitosan microcapsules was strongly depended on the average pore size of the SPG membrane and the amount of menthol loading in the dispersed phase. The membrane pore size of 5.2 µm was suitable for a viscous dispersed phase containing light mineral oil. The average diameter of emulsion droplets of 28.3 µm was obtained. Increasing the menthol loading in the dispersion phase from 5% to 10% w/w of chitosan decreased the emulsion droplet size with a broad size distribution. The crosslinked microcapsule size and size distribution of mixed emulsion droplets decreased with the increasing crosslinking time. The menthol release was a diffusion control which depended on the proportion of amino group in chitosan-to-tripolyphosphate molar ratio and crosslinking time. This work also demonstrated that hydrophilicity/hydrophobicity of the continuous phase and dispersion phase controlled SPG membrane emulsification efficiency and quality of the resulting emulsion droplets.

Authors+Show Affiliations

Department of Environmental Science, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23398357

Citation

Nuisin, Roongkan, et al. "Microencapsulation of Menthol By Crosslinked Chitosan Via Porous Glass Membrane Emulsification Technique and Their Controlled Release Properties." Journal of Microencapsulation, vol. 30, no. 5, 2013, pp. 498-509.
Nuisin R, Krongsin J, Noppakundilograt S, et al. Microencapsulation of menthol by crosslinked chitosan via porous glass membrane emulsification technique and their controlled release properties. J Microencapsul. 2013;30(5):498-509.
Nuisin, R., Krongsin, J., Noppakundilograt, S., & Kiatkamjornwong, S. (2013). Microencapsulation of menthol by crosslinked chitosan via porous glass membrane emulsification technique and their controlled release properties. Journal of Microencapsulation, 30(5), 498-509. https://doi.org/10.3109/02652048.2012.758179
Nuisin R, et al. Microencapsulation of Menthol By Crosslinked Chitosan Via Porous Glass Membrane Emulsification Technique and Their Controlled Release Properties. J Microencapsul. 2013;30(5):498-509. PubMed PMID: 23398357.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microencapsulation of menthol by crosslinked chitosan via porous glass membrane emulsification technique and their controlled release properties. AU - Nuisin,Roongkan, AU - Krongsin,Jaruwan, AU - Noppakundilograt,Supaporn, AU - Kiatkamjornwong,Suda, Y1 - 2013/02/12/ PY - 2013/2/13/entrez PY - 2013/2/13/pubmed PY - 2014/1/28/medline SP - 498 EP - 509 JF - Journal of microencapsulation JO - J Microencapsul VL - 30 IS - 5 N2 - Chitosan-encapsulated menthol microcapsules were successfully prepared in an oil-in-water (o/w) emulsion using the Shirasu Porous Glass (SPG) membrane emulsification technique and high-speed dispersion technique for preparing a mixed o/w emulsion. The size of the menthol-loaded chitosan microcapsules was strongly depended on the average pore size of the SPG membrane and the amount of menthol loading in the dispersed phase. The membrane pore size of 5.2 µm was suitable for a viscous dispersed phase containing light mineral oil. The average diameter of emulsion droplets of 28.3 µm was obtained. Increasing the menthol loading in the dispersion phase from 5% to 10% w/w of chitosan decreased the emulsion droplet size with a broad size distribution. The crosslinked microcapsule size and size distribution of mixed emulsion droplets decreased with the increasing crosslinking time. The menthol release was a diffusion control which depended on the proportion of amino group in chitosan-to-tripolyphosphate molar ratio and crosslinking time. This work also demonstrated that hydrophilicity/hydrophobicity of the continuous phase and dispersion phase controlled SPG membrane emulsification efficiency and quality of the resulting emulsion droplets. SN - 1464-5246 UR - https://www.unboundmedicine.com/medline/citation/23398357/Microencapsulation_of_menthol_by_crosslinked_chitosan_via_porous_glass_membrane_emulsification_technique_and_their_controlled_release_properties_ L2 - https://www.tandfonline.com/doi/full/10.3109/02652048.2012.758179 DB - PRIME DP - Unbound Medicine ER -