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Tarlov cysts: clinical evaluation of an italian cohort of patients.
Neurol Sci. 2013 Sep; 34(9):1679-82.NS

Abstract

Tarlov cyst syndrome is a rare, often asymptomatic disorder, characterised by isolated or multiple nerve-root cysts, usually occurring in the sacral spine, near the dorsal root ganglion, between the perineurium and endoneurium. The cysts may cause lower back pain, sacral radiculopathy, dyspareunia and urinary incontinence. There is little data in the literature on the relationship between Tarlov cysts and symptoms. Here, we report further details on the clinical impact of Tarlov cysts and investigate their pathogenesis and role as a cause of lumbosacral symptoms. We examined 157 patients with MRI evidence of symptomatic Tarlov cysts. Patients underwent complete neurological examination and were scored by the Hamilton Depression Rating Scale and the Visual Analogue Scale. Complete lower limb electromyography was performed in 32 patients. Clinical picture was correlated with size and number of cysts detected by MRI. Family history was recorded for signs of genetic inheritance. Almost all patients suffered perineal or lower back pain; 34 complained of sphincter and 46 of sexual disorders. Hamilton scores were abnormal, and family history was positive in a few cases. The scanty literature on Tarlov cysts mainly regards therapy by a neurosurgical approach. Our results provide new data on clinical impact and possible pathogenetic mechanisms.

Authors+Show Affiliations

Department of Neurological, Behavioural and Neurosurgical Sciences, Medical School, University of Siena, Viale Bracci 2, 53100, Siena, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23400656

Citation

Marino, D, et al. "Tarlov Cysts: Clinical Evaluation of an Italian Cohort of Patients." Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, vol. 34, no. 9, 2013, pp. 1679-82.
Marino D, Carluccio MA, Di Donato I, et al. Tarlov cysts: clinical evaluation of an italian cohort of patients. Neurol Sci. 2013;34(9):1679-82.
Marino, D., Carluccio, M. A., Di Donato, I., Sicurelli, F., Chini, E., Di Toro Mammarella, L., Rossi, F., Rubegni, A., & Federico, A. (2013). Tarlov cysts: clinical evaluation of an italian cohort of patients. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 34(9), 1679-82. https://doi.org/10.1007/s10072-013-1321-0
Marino D, et al. Tarlov Cysts: Clinical Evaluation of an Italian Cohort of Patients. Neurol Sci. 2013;34(9):1679-82. PubMed PMID: 23400656.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tarlov cysts: clinical evaluation of an italian cohort of patients. AU - Marino,D, AU - Carluccio,M A, AU - Di Donato,I, AU - Sicurelli,F, AU - Chini,E, AU - Di Toro Mammarella,L, AU - Rossi,F, AU - Rubegni,A, AU - Federico,A, Y1 - 2013/02/12/ PY - 2012/09/16/received PY - 2013/01/22/accepted PY - 2013/2/13/entrez PY - 2013/2/13/pubmed PY - 2014/6/3/medline SP - 1679 EP - 82 JF - Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology JO - Neurol. Sci. VL - 34 IS - 9 N2 - Tarlov cyst syndrome is a rare, often asymptomatic disorder, characterised by isolated or multiple nerve-root cysts, usually occurring in the sacral spine, near the dorsal root ganglion, between the perineurium and endoneurium. The cysts may cause lower back pain, sacral radiculopathy, dyspareunia and urinary incontinence. There is little data in the literature on the relationship between Tarlov cysts and symptoms. Here, we report further details on the clinical impact of Tarlov cysts and investigate their pathogenesis and role as a cause of lumbosacral symptoms. We examined 157 patients with MRI evidence of symptomatic Tarlov cysts. Patients underwent complete neurological examination and were scored by the Hamilton Depression Rating Scale and the Visual Analogue Scale. Complete lower limb electromyography was performed in 32 patients. Clinical picture was correlated with size and number of cysts detected by MRI. Family history was recorded for signs of genetic inheritance. Almost all patients suffered perineal or lower back pain; 34 complained of sphincter and 46 of sexual disorders. Hamilton scores were abnormal, and family history was positive in a few cases. The scanty literature on Tarlov cysts mainly regards therapy by a neurosurgical approach. Our results provide new data on clinical impact and possible pathogenetic mechanisms. SN - 1590-3478 UR - https://www.unboundmedicine.com/medline/citation/23400656/Tarlov_cysts:_clinical_evaluation_of_an_italian_cohort_of_patients_ L2 - https://dx.doi.org/10.1007/s10072-013-1321-0 DB - PRIME DP - Unbound Medicine ER -