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Boston type 1 keratoprosthesis outcomes in ocular burns.
Acta Ophthalmol 2013; 91(6):e432-6AO

Abstract

PURPOSE

To report the outcomes of Boston type I keratoprosthesis (BKPro) in the management of ocular burn injuries.

METHODS

This was a prospective study including all cases of BKPro implantation for ocular burns at the External Diseases and Cornea Service of the Federal University of São Paulo, between February 2008 and February 2010. Ten patients (10 eyes) were enrolled. Procedures performed to manage ocular injury were identified, and data were collected regarding patients' ocular history, surgical procedure(s) performed, and postoperative outcomes, including visual acuity, retention, complications and required surgical procedures.

RESULTS

A total of 11 Type 1 BKPro were implanted in 10 eyes of 10 patients. The mean follow-up period was 25.7 ± 10.8 months. Preoperative best-corrected visual acuity (BCVA) ranged from count fingers to light perception. Postoperative BCVA was better than 20/200 in 90% of the patients and better than 20/60 in 60% of the patients. The overall BKPro retention rate was 90%. The most common complications were retroprosthetic membrane formation (50%) and persistent corneal epithelial defect evolving to corneal melting (40%). Patients who underwent ocular surface procedures such as limbal transplantation prior to BKPRo implantation had a lower incidence of corneal melting/thinning (p = 0.07), although this was not statistically significant.

CONCLUSION

The anatomical and functional results identified in this study support the use of BKPro in managing bilateral limbal stem cell deficiency secondary to ocular burns.

Authors+Show Affiliations

Department of Ophthalmology, Federal University of São Paulo, Brazil. fernandapedreiramagalhaes@yahoo.com.brNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23406295

Citation

Magalhães, Fernanda Pedreira, et al. "Boston Type 1 Keratoprosthesis Outcomes in Ocular Burns." Acta Ophthalmologica, vol. 91, no. 6, 2013, pp. e432-6.
Magalhães FP, Hirai FE, de Sousa LB, et al. Boston type 1 keratoprosthesis outcomes in ocular burns. Acta Ophthalmol. 2013;91(6):e432-6.
Magalhães, F. P., Hirai, F. E., de Sousa, L. B., & de Oliveira, L. A. (2013). Boston type 1 keratoprosthesis outcomes in ocular burns. Acta Ophthalmologica, 91(6), pp. e432-6. doi:10.1111/aos.12083.
Magalhães FP, et al. Boston Type 1 Keratoprosthesis Outcomes in Ocular Burns. Acta Ophthalmol. 2013;91(6):e432-6. PubMed PMID: 23406295.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Boston type 1 keratoprosthesis outcomes in ocular burns. AU - Magalhães,Fernanda Pedreira, AU - Hirai,Flavio Eduardo, AU - de Sousa,Luciene Barbosa, AU - de Oliveira,Lauro Augusto, Y1 - 2013/02/14/ PY - 2013/2/15/entrez PY - 2013/2/15/pubmed PY - 2014/2/13/medline KW - chemical burn KW - keratoprosthesis KW - ocular injury SP - e432 EP - 6 JF - Acta ophthalmologica JO - Acta Ophthalmol VL - 91 IS - 6 N2 - PURPOSE: To report the outcomes of Boston type I keratoprosthesis (BKPro) in the management of ocular burn injuries. METHODS: This was a prospective study including all cases of BKPro implantation for ocular burns at the External Diseases and Cornea Service of the Federal University of São Paulo, between February 2008 and February 2010. Ten patients (10 eyes) were enrolled. Procedures performed to manage ocular injury were identified, and data were collected regarding patients' ocular history, surgical procedure(s) performed, and postoperative outcomes, including visual acuity, retention, complications and required surgical procedures. RESULTS: A total of 11 Type 1 BKPro were implanted in 10 eyes of 10 patients. The mean follow-up period was 25.7 ± 10.8 months. Preoperative best-corrected visual acuity (BCVA) ranged from count fingers to light perception. Postoperative BCVA was better than 20/200 in 90% of the patients and better than 20/60 in 60% of the patients. The overall BKPro retention rate was 90%. The most common complications were retroprosthetic membrane formation (50%) and persistent corneal epithelial defect evolving to corneal melting (40%). Patients who underwent ocular surface procedures such as limbal transplantation prior to BKPRo implantation had a lower incidence of corneal melting/thinning (p = 0.07), although this was not statistically significant. CONCLUSION: The anatomical and functional results identified in this study support the use of BKPro in managing bilateral limbal stem cell deficiency secondary to ocular burns. SN - 1755-3768 UR - https://www.unboundmedicine.com/medline/citation/23406295/Boston_type_1_keratoprosthesis_outcomes_in_ocular_burns_ L2 - https://doi.org/10.1111/aos.12083 DB - PRIME DP - Unbound Medicine ER -