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Antimicrobial and antioxidant activities of alcoholic extracts of Rumex dentatus L.
Microb Pathog. 2013 Apr; 57:17-20.MP

Abstract

In-vitro antimicrobial and antioxidant activities of various concentrations ranging from 150 to 500 μg/ml of alcoholic (methanol and ethanol) extracts of Rumex dentatus were analyzed on different clinical bacterial strains (Shigella flexneri, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus) and fungal strains (Aspergillus versicolor, Aspergillus flavus, Acremonium spp., Penicillium dimorphosporum, Candida albicans, Candida kruesie, Candida parapsilosis) using agar disk diffusion method and broth dilution method (MIC and MBC determination) for antimicrobial activity and DPPH (1,1-diphenyl-2-picrylhydrazyl) assay, Riboflavin photo-oxidation assay, deoxyribose assay, lipid peroxidation assay for antioxidant activity. The extracts showed maximum inhibitory effect against K. pneumonia and P. aeruginosa with no activity against S. typhimurium from among the bacterial strains while as in case of the fungal strains the maximum effect was observed against C. albicans by both the extracts. MIC and MBC values determined for active fractions of the extracts against some bacterial strains (S. flexneri, K. pneumonia and E. coli) revealed that the test organisms were inhibited by all the extracts with methanol showing lower values of both MIC and MBC indicating it as a better antimicrobial agent. The antioxidant activity showed that the extracts exhibited scavenging effect in concentration-dependent manner on superoxide anion radicals and hydroxyl radicals leading to the conclusion that the plant has got a broad spectrum antimicrobial and antioxidant activity and could be a potential alternative for treating various diseases.

Authors+Show Affiliations

Centre of Research for Development, University of Kashmir, Srinagar 190 006, India. humeranissa2@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23415966

Citation

Humeera, Nisa, et al. "Antimicrobial and Antioxidant Activities of Alcoholic Extracts of Rumex Dentatus L." Microbial Pathogenesis, vol. 57, 2013, pp. 17-20.
Humeera N, Kamili AN, Bandh SA, et al. Antimicrobial and antioxidant activities of alcoholic extracts of Rumex dentatus L. Microb Pathog. 2013;57:17-20.
Humeera, N., Kamili, A. N., Bandh, S. A., Amin, S. U., Lone, B. A., & Gousia, N. (2013). Antimicrobial and antioxidant activities of alcoholic extracts of Rumex dentatus L. Microbial Pathogenesis, 57, 17-20. https://doi.org/10.1016/j.micpath.2013.02.001
Humeera N, et al. Antimicrobial and Antioxidant Activities of Alcoholic Extracts of Rumex Dentatus L. Microb Pathog. 2013;57:17-20. PubMed PMID: 23415966.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial and antioxidant activities of alcoholic extracts of Rumex dentatus L. AU - Humeera,Nisa, AU - Kamili,Azra N, AU - Bandh,Suhaib A, AU - Amin,Shajr-ul-, AU - Lone,Bashir A, AU - Gousia,Nisa, Y1 - 2013/02/13/ PY - 2012/12/22/received PY - 2013/02/02/accepted PY - 2013/2/19/entrez PY - 2013/2/19/pubmed PY - 2013/9/24/medline SP - 17 EP - 20 JF - Microbial pathogenesis JO - Microb Pathog VL - 57 N2 - In-vitro antimicrobial and antioxidant activities of various concentrations ranging from 150 to 500 μg/ml of alcoholic (methanol and ethanol) extracts of Rumex dentatus were analyzed on different clinical bacterial strains (Shigella flexneri, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus) and fungal strains (Aspergillus versicolor, Aspergillus flavus, Acremonium spp., Penicillium dimorphosporum, Candida albicans, Candida kruesie, Candida parapsilosis) using agar disk diffusion method and broth dilution method (MIC and MBC determination) for antimicrobial activity and DPPH (1,1-diphenyl-2-picrylhydrazyl) assay, Riboflavin photo-oxidation assay, deoxyribose assay, lipid peroxidation assay for antioxidant activity. The extracts showed maximum inhibitory effect against K. pneumonia and P. aeruginosa with no activity against S. typhimurium from among the bacterial strains while as in case of the fungal strains the maximum effect was observed against C. albicans by both the extracts. MIC and MBC values determined for active fractions of the extracts against some bacterial strains (S. flexneri, K. pneumonia and E. coli) revealed that the test organisms were inhibited by all the extracts with methanol showing lower values of both MIC and MBC indicating it as a better antimicrobial agent. The antioxidant activity showed that the extracts exhibited scavenging effect in concentration-dependent manner on superoxide anion radicals and hydroxyl radicals leading to the conclusion that the plant has got a broad spectrum antimicrobial and antioxidant activity and could be a potential alternative for treating various diseases. SN - 1096-1208 UR - https://www.unboundmedicine.com/medline/citation/23415966/Antimicrobial_and_antioxidant_activities_of_alcoholic_extracts_of_Rumex_dentatus_L_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0882-4010(13)00013-2 DB - PRIME DP - Unbound Medicine ER -