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A cyclic pain: the pathophysiology and treatment of menstrual migraine.
Obstet Gynecol Surv. 2013 Feb; 68(2):130-40.OG

Abstract

Catamenial migraine is a headache disorder occurring in reproductive-aged women relevant to menstrual cycles. Catamenial migraine is defined as attacks of migraine that occurs regularly in at least 2 of 3 consecutive menstrual cycles and occurs exclusively on day 1 to 2 of menstruation, but may range from 2 days before (defined as -2) to 3 days after (defined as +3 with the first day of menstruation as day +1). There are 2 subtypes: the pure menstrual migraine and menstrually related migraine. In pure menstrual migraine, there are no aura and no migraine occurring during any other time of the menstrual cycle. In contrast, menstrually related migraine also occurs in 2 of 3 consecutive menstrual cycles, mostly on days 1 and 2 of menstruation, but it may occur outside the menstrual cycle. Catamenial migraine significantly interferes with the quality of life and causes functional disability in most sufferers. The fluctuation of estrogen levels is believed to play a role in the pathogenesis of catamenial migraine. In this review, we discuss estrogen and its direct and indirect pathophysiologic roles in menstrual-related migraine headaches and the available treatment for women.

TARGET AUDIENCE

Obstetricians and gynecologists, family physicians.

LEARNING OBJECTIVES

After completing this CME activity, physicians should be better able to discuss the pathophysiology of catamenial migraine, identify the risk factors for catamenial migraine among women, and list the prophylactic and abortive treatments for migraines.

Authors+Show Affiliations

Harvard Medical School, Boston, MA, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23417219

Citation

Mathew, Paul G., et al. "A Cyclic Pain: the Pathophysiology and Treatment of Menstrual Migraine." Obstetrical & Gynecological Survey, vol. 68, no. 2, 2013, pp. 130-40.
Mathew PG, Dun EC, Luo JJ. A cyclic pain: the pathophysiology and treatment of menstrual migraine. Obstet Gynecol Surv. 2013;68(2):130-40.
Mathew, P. G., Dun, E. C., & Luo, J. J. (2013). A cyclic pain: the pathophysiology and treatment of menstrual migraine. Obstetrical & Gynecological Survey, 68(2), 130-40. https://doi.org/10.1097/OGX.0b013e31827f2496
Mathew PG, Dun EC, Luo JJ. A Cyclic Pain: the Pathophysiology and Treatment of Menstrual Migraine. Obstet Gynecol Surv. 2013;68(2):130-40. PubMed PMID: 23417219.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A cyclic pain: the pathophysiology and treatment of menstrual migraine. AU - Mathew,Paul G, AU - Dun,Erica C, AU - Luo,Jin Jun, PY - 2013/2/19/entrez PY - 2013/2/19/pubmed PY - 2013/7/28/medline SP - 130 EP - 40 JF - Obstetrical & gynecological survey JO - Obstet Gynecol Surv VL - 68 IS - 2 N2 - UNLABELLED: Catamenial migraine is a headache disorder occurring in reproductive-aged women relevant to menstrual cycles. Catamenial migraine is defined as attacks of migraine that occurs regularly in at least 2 of 3 consecutive menstrual cycles and occurs exclusively on day 1 to 2 of menstruation, but may range from 2 days before (defined as -2) to 3 days after (defined as +3 with the first day of menstruation as day +1). There are 2 subtypes: the pure menstrual migraine and menstrually related migraine. In pure menstrual migraine, there are no aura and no migraine occurring during any other time of the menstrual cycle. In contrast, menstrually related migraine also occurs in 2 of 3 consecutive menstrual cycles, mostly on days 1 and 2 of menstruation, but it may occur outside the menstrual cycle. Catamenial migraine significantly interferes with the quality of life and causes functional disability in most sufferers. The fluctuation of estrogen levels is believed to play a role in the pathogenesis of catamenial migraine. In this review, we discuss estrogen and its direct and indirect pathophysiologic roles in menstrual-related migraine headaches and the available treatment for women. TARGET AUDIENCE: Obstetricians and gynecologists, family physicians. LEARNING OBJECTIVES: After completing this CME activity, physicians should be better able to discuss the pathophysiology of catamenial migraine, identify the risk factors for catamenial migraine among women, and list the prophylactic and abortive treatments for migraines. SN - 1533-9866 UR - https://www.unboundmedicine.com/medline/citation/23417219/A_cyclic_pain:_the_pathophysiology_and_treatment_of_menstrual_migraine_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=23417219.ui DB - PRIME DP - Unbound Medicine ER -