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[Minute granular lesions of the retinal pigment epithelium related to choroidal hyperpermeability in patients with central serous chorioretinopathy].
Nippon Ganka Gakkai Zasshi. 2013 Jan; 117(1):44-9.NG

Abstract

PURPOSE

To investigate the relationship between increased permeability of choroidal vessels revealed by indocyanine green angiography (ICGA) and lesions of retinal pigment epithelium (RPE) revealed by Retro-mode (RM) in the eyes of patients with central serous chorioretinopathy (CSC).

DESIGN

A retrospective cross-sectional study.

PATIENTS AND METHODS

We examined the minute granular lesions (MGLs) of the RPE using RM imaging (scanning laser ophthalmoscopy), in relation to the choroidal hyperpermeability visualized by indocyanine green angiography (ICGA) in 40 eyes of 20 Japanese patients with CSC. We classified them into two groups: eyes (25 eyes) with various retinal lesions and eyes without retinal lesions (15 eyes).

RESULTS

MGLs of the RPE in RM imaging were seen in 38 of 40 eyes (95%). The MGLs were detected in all 25 eyes in the group of various retinal lesions, and in 13 of 15 eyes (87%)in the group without retinal lesions. The area of MGLs exceeded the choroidal hyperpermeability in 18 eyes (45%), was the same as choroidal hyperpermeability in 15 eyes (38%), while 7 eyes (17%) had no hyperpermeability.

CONCLUSIONS

Choroidal hyperpermeability may be a possible cause of MGLs in the eyes of patients with CSC.

Authors+Show Affiliations

Souen Muneyasu Eye Clinic, Japan. takedamnjp@ybb.ne.jpNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

23424975

Citation

Takeda, Muneyasu, and Yui Sato. "[Minute Granular Lesions of the Retinal Pigment Epithelium Related to Choroidal Hyperpermeability in Patients With Central Serous Chorioretinopathy]." Nippon Ganka Gakkai Zasshi, vol. 117, no. 1, 2013, pp. 44-9.
Takeda M, Sato Y. [Minute granular lesions of the retinal pigment epithelium related to choroidal hyperpermeability in patients with central serous chorioretinopathy]. Nippon Ganka Gakkai Zasshi. 2013;117(1):44-9.
Takeda, M., & Sato, Y. (2013). [Minute granular lesions of the retinal pigment epithelium related to choroidal hyperpermeability in patients with central serous chorioretinopathy]. Nippon Ganka Gakkai Zasshi, 117(1), 44-9.
Takeda M, Sato Y. [Minute Granular Lesions of the Retinal Pigment Epithelium Related to Choroidal Hyperpermeability in Patients With Central Serous Chorioretinopathy]. Nippon Ganka Gakkai Zasshi. 2013;117(1):44-9. PubMed PMID: 23424975.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Minute granular lesions of the retinal pigment epithelium related to choroidal hyperpermeability in patients with central serous chorioretinopathy]. AU - Takeda,Muneyasu, AU - Sato,Yui, PY - 2013/2/22/entrez PY - 2013/2/22/pubmed PY - 2013/11/2/medline SP - 44 EP - 9 JF - Nippon Ganka Gakkai zasshi JO - Nippon Ganka Gakkai Zasshi VL - 117 IS - 1 N2 - PURPOSE: To investigate the relationship between increased permeability of choroidal vessels revealed by indocyanine green angiography (ICGA) and lesions of retinal pigment epithelium (RPE) revealed by Retro-mode (RM) in the eyes of patients with central serous chorioretinopathy (CSC). DESIGN: A retrospective cross-sectional study. PATIENTS AND METHODS: We examined the minute granular lesions (MGLs) of the RPE using RM imaging (scanning laser ophthalmoscopy), in relation to the choroidal hyperpermeability visualized by indocyanine green angiography (ICGA) in 40 eyes of 20 Japanese patients with CSC. We classified them into two groups: eyes (25 eyes) with various retinal lesions and eyes without retinal lesions (15 eyes). RESULTS: MGLs of the RPE in RM imaging were seen in 38 of 40 eyes (95%). The MGLs were detected in all 25 eyes in the group of various retinal lesions, and in 13 of 15 eyes (87%)in the group without retinal lesions. The area of MGLs exceeded the choroidal hyperpermeability in 18 eyes (45%), was the same as choroidal hyperpermeability in 15 eyes (38%), while 7 eyes (17%) had no hyperpermeability. CONCLUSIONS: Choroidal hyperpermeability may be a possible cause of MGLs in the eyes of patients with CSC. SN - 0029-0203 UR - https://www.unboundmedicine.com/medline/citation/23424975/[Minute_granular_lesions_of_the_retinal_pigment_epithelium_related_to_choroidal_hyperpermeability_in_patients_with_central_serous_chorioretinopathy]_ L2 - http://www.medicalonline.jp/meteo_linkout.php?issn=0029-0203&volume=117&issue=1&spage=44 DB - PRIME DP - Unbound Medicine ER -