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Mycoplasma genitalium: prevalence in men presenting with urethritis to a South Australian public sexual health clinic.
Intern Med J. 2013 May; 43(5):494-500.IM

Abstract

BACKGROUND/AIM

This study aimed to determine the prevalence of Mycoplasma genitalium infection among male patients with dysuria and/or urethral discharge. An analysis of the clinical, demographic and microbiological factors associated with M. genitalium infection was also conducted.

METHOD

From May 2007 to June 2011, men presenting to the clinic with self-reported symptoms of dysuria and/or urethral discharge were identified and underwent urethral swab, which was microscopically assessed for objective non-gonococcal urethritis. A first-void urine sample was tested for Chlamydia trachomatis and Neisseria gonorrhoeae using the Aptima Combo-2 assay. A portion of the urine sample was sent for polymerase chain reaction analysis for M. genitalium.

RESULTS

One thousand, one hundred and eighty-two men with dysuria and/or urethral discharge were tested for M. genitalium. Of those, 96 men (8.1%) were positive for M. genitalium. Men identifying as solely MSM (men who have sex with men) constituted 16.3% (n = 193) of the sample. Their infection rate was 3.1% (n = 6). The infection rate for heterosexual and bisexual men was 9.1%. For all men, the M. genitalium co-infection rate was 14.6% (n = 14) with C. trachomatis and 3.1% (n = 3) with N. gonorrhoeae. Factors associated with M. genitalium infection were analysed by univariate analysis. We determined that five investigated predictors were significantly associated with M. genitalium infection, urethral discharge, non-gonococcal urethritis on Gram stain of urethral smears, identification as heterosexual or bisexual, and absence of co-infection with C. trachomatis or N. gonorrhoeae.

CONCLUSION

In Adelaide, M. genitalium is an important sexually transmitted infection among men with dysuria and/or urethral discharge, and is primarily an infection of heterosexual and bisexual men.

Authors+Show Affiliations

Clinic 275, Royal Adelaide Hospital, Adelaide, South Australia, Australia. tonia_mezzini@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23425506

Citation

Mezzini, T M., et al. "Mycoplasma Genitalium: Prevalence in Men Presenting With Urethritis to a South Australian Public Sexual Health Clinic." Internal Medicine Journal, vol. 43, no. 5, 2013, pp. 494-500.
Mezzini TM, Waddell RG, Douglas RJ, et al. Mycoplasma genitalium: prevalence in men presenting with urethritis to a South Australian public sexual health clinic. Intern Med J. 2013;43(5):494-500.
Mezzini, T. M., Waddell, R. G., Douglas, R. J., & Sadlon, T. A. (2013). Mycoplasma genitalium: prevalence in men presenting with urethritis to a South Australian public sexual health clinic. Internal Medicine Journal, 43(5), 494-500. https://doi.org/10.1111/imj.12103
Mezzini TM, et al. Mycoplasma Genitalium: Prevalence in Men Presenting With Urethritis to a South Australian Public Sexual Health Clinic. Intern Med J. 2013;43(5):494-500. PubMed PMID: 23425506.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mycoplasma genitalium: prevalence in men presenting with urethritis to a South Australian public sexual health clinic. AU - Mezzini,T M, AU - Waddell,R G, AU - Douglas,R J, AU - Sadlon,T A, PY - 2012/08/22/received PY - 2013/02/03/accepted PY - 2013/2/22/entrez PY - 2013/2/22/pubmed PY - 2014/2/20/medline SP - 494 EP - 500 JF - Internal medicine journal JO - Intern Med J VL - 43 IS - 5 N2 - BACKGROUND/AIM: This study aimed to determine the prevalence of Mycoplasma genitalium infection among male patients with dysuria and/or urethral discharge. An analysis of the clinical, demographic and microbiological factors associated with M. genitalium infection was also conducted. METHOD: From May 2007 to June 2011, men presenting to the clinic with self-reported symptoms of dysuria and/or urethral discharge were identified and underwent urethral swab, which was microscopically assessed for objective non-gonococcal urethritis. A first-void urine sample was tested for Chlamydia trachomatis and Neisseria gonorrhoeae using the Aptima Combo-2 assay. A portion of the urine sample was sent for polymerase chain reaction analysis for M. genitalium. RESULTS: One thousand, one hundred and eighty-two men with dysuria and/or urethral discharge were tested for M. genitalium. Of those, 96 men (8.1%) were positive for M. genitalium. Men identifying as solely MSM (men who have sex with men) constituted 16.3% (n = 193) of the sample. Their infection rate was 3.1% (n = 6). The infection rate for heterosexual and bisexual men was 9.1%. For all men, the M. genitalium co-infection rate was 14.6% (n = 14) with C. trachomatis and 3.1% (n = 3) with N. gonorrhoeae. Factors associated with M. genitalium infection were analysed by univariate analysis. We determined that five investigated predictors were significantly associated with M. genitalium infection, urethral discharge, non-gonococcal urethritis on Gram stain of urethral smears, identification as heterosexual or bisexual, and absence of co-infection with C. trachomatis or N. gonorrhoeae. CONCLUSION: In Adelaide, M. genitalium is an important sexually transmitted infection among men with dysuria and/or urethral discharge, and is primarily an infection of heterosexual and bisexual men. SN - 1445-5994 UR - https://www.unboundmedicine.com/medline/citation/23425506/Mycoplasma_genitalium:_prevalence_in_men_presenting_with_urethritis_to_a_South_Australian_public_sexual_health_clinic_ DB - PRIME DP - Unbound Medicine ER -