Tags

Type your tag names separated by a space and hit enter

Studies on the prevention of 5-fluorouracil-induced oral mucositis.
NCI Monogr. 1990NM

Abstract

Oral mucositis is a major toxic effect related to 5-fluorouracil (5-FU) therapy. Clinical studies have attempted to identify an effective antidote for this untoward side effect. Early pilot studies suggested that an allopurinol mouthwash could lessen 5-FU-induced mucositis. However, a randomized, double-blinded, placebo-controlled crossover study did not suggest that an allopurinol mouthwash had any prophylactic value in this clinical situation. An ongoing, randomized clinical protocol is testing cryotherapy as a method of inhibiting 5-FU-induced stomatitis. No clinically appropriate prophylactic measure for preventing 5-FU-induced mucositis has been found to date.

Authors+Show Affiliations

Mayo Clinic, Rochester, MN 55905.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2342597

Citation

Loprinzi, C L., and A M. Dose. "Studies On the Prevention of 5-fluorouracil-induced Oral Mucositis." NCI Monographs : a Publication of the National Cancer Institute, 1990, pp. 93-4.
Loprinzi CL, Dose AM. Studies on the prevention of 5-fluorouracil-induced oral mucositis. NCI Monogr. 1990.
Loprinzi, C. L., & Dose, A. M. (1990). Studies on the prevention of 5-fluorouracil-induced oral mucositis. NCI Monographs : a Publication of the National Cancer Institute, (9), 93-4.
Loprinzi CL, Dose AM. Studies On the Prevention of 5-fluorouracil-induced Oral Mucositis. NCI Monogr. 1990;(9)93-4. PubMed PMID: 2342597.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Studies on the prevention of 5-fluorouracil-induced oral mucositis. AU - Loprinzi,C L, AU - Dose,A M, PY - 1990/1/1/pubmed PY - 1990/1/1/medline PY - 1990/1/1/entrez SP - 93 EP - 4 JF - NCI monographs : a publication of the National Cancer Institute JO - NCI Monogr IS - 9 N2 - Oral mucositis is a major toxic effect related to 5-fluorouracil (5-FU) therapy. Clinical studies have attempted to identify an effective antidote for this untoward side effect. Early pilot studies suggested that an allopurinol mouthwash could lessen 5-FU-induced mucositis. However, a randomized, double-blinded, placebo-controlled crossover study did not suggest that an allopurinol mouthwash had any prophylactic value in this clinical situation. An ongoing, randomized clinical protocol is testing cryotherapy as a method of inhibiting 5-FU-induced stomatitis. No clinically appropriate prophylactic measure for preventing 5-FU-induced mucositis has been found to date. SN - 0893-2751 UR - https://www.unboundmedicine.com/medline/citation/2342597/Studies_on_the_prevention_of_5_fluorouracil_induced_oral_mucositis_ DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.