Tags

Type your tag names separated by a space and hit enter

Flat ductal intraepithelial neoplasia 1A diagnosed at stereotactic core needle biopsy: is excisional biopsy indicated?
AJR Am J Roentgenol. 2013 Mar; 200(3):682-8.AA

Abstract

OBJECTIVE

This study correlates ductal intraepithelial neoplasia (DIN) 1A diagnosed at stereotactic spring core needle biopsy (CNB) or vacuum-assisted biopsy (VAB) with the subsequent surgical histologic results or long-term follow-up imaging findings to predict the likelihood of upgrade to ductal carcinoma in situ (DCIS) or invasive carcinoma.

MATERIALS AND METHODS

Stereotactic imaging-guided CNBs and VABs were performed principally for assessment of microcalcifications seen on mammography. DIN 1A diagnoses made at CNB or VAB were correlated with subsequent excisional biopsy results or imaging follow-up. Patients were included only if there was no concomitant CNB or VAB diagnosis of DIN 1B, atypical lobular hyperplasia, lobular carcinoma in situ or DCIS, papillary lesion, or invasive carcinoma. Surgical biopsy results were obtained for 239 patients. Upgrade was defined as a diagnosis of DCIS or invasive carcinoma at surgery. Patients who did not undergo surgical excision were followed with imaging.

RESULTS

An upgrade rate of 4.2% (10 lesions in 239 patients) is reported. The remaining samples (229/239) had a surgical diagnosis of DIN 1A or DIN 1B, lobular carcinoma in situ, or a benign finding with no atypia.

CONCLUSION

The upgrade rate of DIN 1A diagnosed at CNB or VAB was 4.2%. These results indicate it may be reasonable to avert immediate surgery in favor of short-term imaging follow-up.

Authors+Show Affiliations

Department of Radiology, University of British Columbia, Vancouver, BC, Canada. Becker.annalisa@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

23436863

Citation

Becker, Annalisa K., et al. "Flat Ductal Intraepithelial Neoplasia 1A Diagnosed at Stereotactic Core Needle Biopsy: Is Excisional Biopsy Indicated?" AJR. American Journal of Roentgenology, vol. 200, no. 3, 2013, pp. 682-8.
Becker AK, Gordon PB, Harrison DA, et al. Flat ductal intraepithelial neoplasia 1A diagnosed at stereotactic core needle biopsy: is excisional biopsy indicated? AJR Am J Roentgenol. 2013;200(3):682-8.
Becker, A. K., Gordon, P. B., Harrison, D. A., Hassell, P. R., Hayes, M. M., van Niekerk, D., & Wilson, C. M. (2013). Flat ductal intraepithelial neoplasia 1A diagnosed at stereotactic core needle biopsy: is excisional biopsy indicated? AJR. American Journal of Roentgenology, 200(3), 682-8. https://doi.org/10.2214/AJR.11.8090
Becker AK, et al. Flat Ductal Intraepithelial Neoplasia 1A Diagnosed at Stereotactic Core Needle Biopsy: Is Excisional Biopsy Indicated. AJR Am J Roentgenol. 2013;200(3):682-8. PubMed PMID: 23436863.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Flat ductal intraepithelial neoplasia 1A diagnosed at stereotactic core needle biopsy: is excisional biopsy indicated? AU - Becker,Annalisa K, AU - Gordon,Paula B, AU - Harrison,Dorothy A, AU - Hassell,Patricia R, AU - Hayes,Malcolm M, AU - van Niekerk,Dirk, AU - Wilson,Christine M, PY - 2013/2/26/entrez PY - 2013/2/26/pubmed PY - 2013/4/12/medline SP - 682 EP - 8 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 200 IS - 3 N2 - OBJECTIVE: This study correlates ductal intraepithelial neoplasia (DIN) 1A diagnosed at stereotactic spring core needle biopsy (CNB) or vacuum-assisted biopsy (VAB) with the subsequent surgical histologic results or long-term follow-up imaging findings to predict the likelihood of upgrade to ductal carcinoma in situ (DCIS) or invasive carcinoma. MATERIALS AND METHODS: Stereotactic imaging-guided CNBs and VABs were performed principally for assessment of microcalcifications seen on mammography. DIN 1A diagnoses made at CNB or VAB were correlated with subsequent excisional biopsy results or imaging follow-up. Patients were included only if there was no concomitant CNB or VAB diagnosis of DIN 1B, atypical lobular hyperplasia, lobular carcinoma in situ or DCIS, papillary lesion, or invasive carcinoma. Surgical biopsy results were obtained for 239 patients. Upgrade was defined as a diagnosis of DCIS or invasive carcinoma at surgery. Patients who did not undergo surgical excision were followed with imaging. RESULTS: An upgrade rate of 4.2% (10 lesions in 239 patients) is reported. The remaining samples (229/239) had a surgical diagnosis of DIN 1A or DIN 1B, lobular carcinoma in situ, or a benign finding with no atypia. CONCLUSION: The upgrade rate of DIN 1A diagnosed at CNB or VAB was 4.2%. These results indicate it may be reasonable to avert immediate surgery in favor of short-term imaging follow-up. SN - 1546-3141 UR - https://www.unboundmedicine.com/medline/citation/23436863/Flat_ductal_intraepithelial_neoplasia_1A_diagnosed_at_stereotactic_core_needle_biopsy:_is_excisional_biopsy_indicated L2 - https://www.ajronline.org/doi/10.2214/AJR.11.8090 DB - PRIME DP - Unbound Medicine ER -