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Red meat and poultry intakes and risk of total and cause-specific mortality: results from cohort studies of Chinese adults in Shanghai.
PLoS One 2013; 8(2):e56963Plos

Abstract

Most previous studies of meat intake and total or cause-specific mortality were conducted in North America, whereas studies in other areas have been limited and reported inconsistent results. This study investigated the association of red meat or poultry intake with risk of total and cause-specific mortality, including cancer and cardiovascular disease (CVD), in two large population-based prospective cohort studies of 134,290 Chinese adult women and men in Shanghai. Meat intakes were assessed through validated food frequency questionnaires administered in person at baseline. Vital status and dates and causes of deaths were ascertained through annual linkage to the Shanghai Vital Statistics Registry and Shanghai Cancer Registry databases and home visits every 2-3 years. Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for the risk of death associated with quintiles of meat intake. During 803,265 person-years of follow up for women and 334,281 person-years of follow up for men, a total of 4,210 deaths in women and 2,733 deaths in men accrued. The median intakes of red meat were 43 g/day among women and 54 g/day among men, and pork constituted at least 95% of total meat intake for both women and men. Red meat intake was associated with increased total mortality among men, but not among women; the HR (95% CI) comparing the highest with the lowest quintiles were 1.18 (1.02-1.35) and 0.92 (0.82-1.03), respectively. This sex difference was statistically significant (P = 0.01). Red meat intake was associated with increased risk of ischemic heart disease mortality (HR = 1.41, 95% CI = 1.05-1.89) and with decreased risk of hemorrhagic stroke mortality (HR = 0.62, 95% CI = 0.45-0.87). There were suggestive inverse associations of poultry intake with risk of total and all-CVD mortality among men, but not among women. Further investigations are needed to elucidate the sex-specific associations between red meat intake and mortality.

Authors+Show Affiliations

Vanderbilt Epidemiology Center, Vanderbilt University, Nashville, Tennessee, United States of America.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

23451121

Citation

Takata, Yumie, et al. "Red Meat and Poultry Intakes and Risk of Total and Cause-specific Mortality: Results From Cohort Studies of Chinese Adults in Shanghai." PloS One, vol. 8, no. 2, 2013, pp. e56963.
Takata Y, Shu XO, Gao YT, et al. Red meat and poultry intakes and risk of total and cause-specific mortality: results from cohort studies of Chinese adults in Shanghai. PLoS ONE. 2013;8(2):e56963.
Takata, Y., Shu, X. O., Gao, Y. T., Li, H., Zhang, X., Gao, J., ... Zheng, W. (2013). Red meat and poultry intakes and risk of total and cause-specific mortality: results from cohort studies of Chinese adults in Shanghai. PloS One, 8(2), pp. e56963. doi:10.1371/journal.pone.0056963.
Takata Y, et al. Red Meat and Poultry Intakes and Risk of Total and Cause-specific Mortality: Results From Cohort Studies of Chinese Adults in Shanghai. PLoS ONE. 2013;8(2):e56963. PubMed PMID: 23451121.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Red meat and poultry intakes and risk of total and cause-specific mortality: results from cohort studies of Chinese adults in Shanghai. AU - Takata,Yumie, AU - Shu,Xiao-Ou, AU - Gao,Yu-Tang, AU - Li,Honglan, AU - Zhang,Xianglan, AU - Gao,Jing, AU - Cai,Hui, AU - Yang,Gong, AU - Xiang,Yong-Bing, AU - Zheng,Wei, Y1 - 2013/02/22/ PY - 2012/10/18/received PY - 2013/01/16/accepted PY - 2013/3/2/entrez PY - 2013/3/2/pubmed PY - 2013/9/4/medline SP - e56963 EP - e56963 JF - PloS one JO - PLoS ONE VL - 8 IS - 2 N2 - Most previous studies of meat intake and total or cause-specific mortality were conducted in North America, whereas studies in other areas have been limited and reported inconsistent results. This study investigated the association of red meat or poultry intake with risk of total and cause-specific mortality, including cancer and cardiovascular disease (CVD), in two large population-based prospective cohort studies of 134,290 Chinese adult women and men in Shanghai. Meat intakes were assessed through validated food frequency questionnaires administered in person at baseline. Vital status and dates and causes of deaths were ascertained through annual linkage to the Shanghai Vital Statistics Registry and Shanghai Cancer Registry databases and home visits every 2-3 years. Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for the risk of death associated with quintiles of meat intake. During 803,265 person-years of follow up for women and 334,281 person-years of follow up for men, a total of 4,210 deaths in women and 2,733 deaths in men accrued. The median intakes of red meat were 43 g/day among women and 54 g/day among men, and pork constituted at least 95% of total meat intake for both women and men. Red meat intake was associated with increased total mortality among men, but not among women; the HR (95% CI) comparing the highest with the lowest quintiles were 1.18 (1.02-1.35) and 0.92 (0.82-1.03), respectively. This sex difference was statistically significant (P = 0.01). Red meat intake was associated with increased risk of ischemic heart disease mortality (HR = 1.41, 95% CI = 1.05-1.89) and with decreased risk of hemorrhagic stroke mortality (HR = 0.62, 95% CI = 0.45-0.87). There were suggestive inverse associations of poultry intake with risk of total and all-CVD mortality among men, but not among women. Further investigations are needed to elucidate the sex-specific associations between red meat intake and mortality. SN - 1932-6203 UR - https://www.unboundmedicine.com/medline/citation/23451121/Red_meat_and_poultry_intakes_and_risk_of_total_and_cause_specific_mortality:_results_from_cohort_studies_of_Chinese_adults_in_Shanghai_ L2 - http://dx.plos.org/10.1371/journal.pone.0056963 DB - PRIME DP - Unbound Medicine ER -