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Vitamin D and gestational diabetes mellitus.
Nutr Rev. 2013 Mar; 71(3):158-67.NR

Abstract

The incidence of gestational diabetes mellitus (GDM) is increasing worldwide. GDM can be responsible for an important proportion of adverse fetal and maternal outcomes during pregnancy, and it is associated with long-term health deterioration for both mother and child. Therefore, it is important to identify potentially modifiable risk factors for GDM. Accumulating evidence links vitamin D deficiency with abnormal glucose metabolism, and epidemiological studies have shown that women who develop GDM are more likely to be vitamin D deficient. This review discusses the prevalence, risk factors, and outcomes of GDM and vitamin D deficiency in pregnant women, outlines the possible mechanism of action of vitamin D in glucose homeostasis, and summarizes emerging evidence that associates vitamin D deficiency with the risk of developing GDM. This critical review of the literature indicates there is a need for intervention trials to test the possible beneficial effect of vitamin D supplementation in pregnant women with low vitamin D status to reduce the risk of developing GDM.

Authors+Show Affiliations

Department of Nutrition, University of Massachusetts, Amherst, Massachusetts 01003, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23452283

Citation

Alzaim, Maysa, and Richard J. Wood. "Vitamin D and Gestational Diabetes Mellitus." Nutrition Reviews, vol. 71, no. 3, 2013, pp. 158-67.
Alzaim M, Wood RJ. Vitamin D and gestational diabetes mellitus. Nutr Rev. 2013;71(3):158-67.
Alzaim, M., & Wood, R. J. (2013). Vitamin D and gestational diabetes mellitus. Nutrition Reviews, 71(3), 158-67. https://doi.org/10.1111/nure.12018
Alzaim M, Wood RJ. Vitamin D and Gestational Diabetes Mellitus. Nutr Rev. 2013;71(3):158-67. PubMed PMID: 23452283.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vitamin D and gestational diabetes mellitus. AU - Alzaim,Maysa, AU - Wood,Richard J, Y1 - 2013/01/29/ PY - 2013/3/5/entrez PY - 2013/3/5/pubmed PY - 2013/4/16/medline SP - 158 EP - 67 JF - Nutrition reviews JO - Nutr Rev VL - 71 IS - 3 N2 - The incidence of gestational diabetes mellitus (GDM) is increasing worldwide. GDM can be responsible for an important proportion of adverse fetal and maternal outcomes during pregnancy, and it is associated with long-term health deterioration for both mother and child. Therefore, it is important to identify potentially modifiable risk factors for GDM. Accumulating evidence links vitamin D deficiency with abnormal glucose metabolism, and epidemiological studies have shown that women who develop GDM are more likely to be vitamin D deficient. This review discusses the prevalence, risk factors, and outcomes of GDM and vitamin D deficiency in pregnant women, outlines the possible mechanism of action of vitamin D in glucose homeostasis, and summarizes emerging evidence that associates vitamin D deficiency with the risk of developing GDM. This critical review of the literature indicates there is a need for intervention trials to test the possible beneficial effect of vitamin D supplementation in pregnant women with low vitamin D status to reduce the risk of developing GDM. SN - 1753-4887 UR - https://www.unboundmedicine.com/medline/citation/23452283/Vitamin_D_and_gestational_diabetes_mellitus_ L2 - https://academic.oup.com/nutritionreviews/article-lookup/doi/10.1111/nure.12018 DB - PRIME DP - Unbound Medicine ER -