Tags

Type your tag names separated by a space and hit enter

Outcome of recurrent pterygium with intraoperative 0.02% mitomycin C and free flap limbal conjunctival autograft.
J Coll Physicians Surg Pak. 2013 Mar; 23(3):199-202.JC

Abstract

OBJECTIVE

To determine the re-recurrence and the postoperative complications in recurrent pterygium cases treated by intraoperative 0.02% Mitomycin C (MMC) and conjunctival autograft (CAG).

STUDY DESIGN

Quasi-experimental.

PLACE AND DURATION OF STUDY

Department of Ophthalmology, Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad and Chandka Medical College Hospital, Larkana, from January to December 2010.

METHODOLOGY

Cases with recurrent pterygium were included in this study. Cases with history of first time pterygium and pterygium with conjunctival scarring, dry eye, glaucoma and vitreoretinal disease were excluded. After topical and subconjunctival anaesthesia, pterygium was excised in single piece. Intraoperative 0.02% MMC was applied on bare sclera for 2 minutes. CAG was excised from supero-temporal conjunctiva, and implanted on bare sclera. All cases were followed-up for 6 months. Re-recurrence was defined as postoperative fibrovascular re-growth of 1.0 mm or more crossing the corneo-scleral limbus. Data was analysed as descriptive statistics.

RESULTS

A total of 65 eyes of 65 cases were studied having mean age of 43.26 ± 12.81 years. Among those, 41 (63.1%) were males and 48 (73.8%) belonged to rural area. The size of pterygium on cornea was 2-3 mm in 44 (67.7%) cases and 4-5 mm in 21 (32.3%) cases. Re-recurrence of pterygium was seen in 3 (4.6%) cases. Postoperative complications included conjunctival granuloma in 2 (3.1%) cases, graft necrosis in 2 (3.1%) cases, graft oedema in 3 (4.6%) cases and graft displacement in 3 (4.6%) cases.

CONCLUSION

The intraoperative application of 0.02% MMC with CAG markedly reduces the risk of re-recurrence of pterygium and postoperative complications.

Authors+Show Affiliations

Department of Ophthalmology, Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23458043

Citation

Narsani, Ashok Kumar, et al. "Outcome of Recurrent Pterygium With Intraoperative 0.02% Mitomycin C and Free Flap Limbal Conjunctival Autograft." Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, vol. 23, no. 3, 2013, pp. 199-202.
Narsani AK, Nagdev PR, Memon MN. Outcome of recurrent pterygium with intraoperative 0.02% mitomycin C and free flap limbal conjunctival autograft. J Coll Physicians Surg Pak. 2013;23(3):199-202.
Narsani, A. K., Nagdev, P. R., & Memon, M. N. (2013). Outcome of recurrent pterygium with intraoperative 0.02% mitomycin C and free flap limbal conjunctival autograft. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 23(3), 199-202. https://doi.org/03.2013/JCPSP.199202
Narsani AK, Nagdev PR, Memon MN. Outcome of Recurrent Pterygium With Intraoperative 0.02% Mitomycin C and Free Flap Limbal Conjunctival Autograft. J Coll Physicians Surg Pak. 2013;23(3):199-202. PubMed PMID: 23458043.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcome of recurrent pterygium with intraoperative 0.02% mitomycin C and free flap limbal conjunctival autograft. AU - Narsani,Ashok Kumar, AU - Nagdev,Partab Rai, AU - Memon,Maria Nazish, PY - 2011/07/15/received PY - 2013/01/18/accepted PY - 2013/3/6/entrez PY - 2013/3/6/pubmed PY - 2013/9/10/medline SP - 199 EP - 202 JF - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP JO - J Coll Physicians Surg Pak VL - 23 IS - 3 N2 - OBJECTIVE: To determine the re-recurrence and the postoperative complications in recurrent pterygium cases treated by intraoperative 0.02% Mitomycin C (MMC) and conjunctival autograft (CAG). STUDY DESIGN: Quasi-experimental. PLACE AND DURATION OF STUDY: Department of Ophthalmology, Liaquat University of Medical and Health Sciences, Jamshoro, Hyderabad and Chandka Medical College Hospital, Larkana, from January to December 2010. METHODOLOGY: Cases with recurrent pterygium were included in this study. Cases with history of first time pterygium and pterygium with conjunctival scarring, dry eye, glaucoma and vitreoretinal disease were excluded. After topical and subconjunctival anaesthesia, pterygium was excised in single piece. Intraoperative 0.02% MMC was applied on bare sclera for 2 minutes. CAG was excised from supero-temporal conjunctiva, and implanted on bare sclera. All cases were followed-up for 6 months. Re-recurrence was defined as postoperative fibrovascular re-growth of 1.0 mm or more crossing the corneo-scleral limbus. Data was analysed as descriptive statistics. RESULTS: A total of 65 eyes of 65 cases were studied having mean age of 43.26 ± 12.81 years. Among those, 41 (63.1%) were males and 48 (73.8%) belonged to rural area. The size of pterygium on cornea was 2-3 mm in 44 (67.7%) cases and 4-5 mm in 21 (32.3%) cases. Re-recurrence of pterygium was seen in 3 (4.6%) cases. Postoperative complications included conjunctival granuloma in 2 (3.1%) cases, graft necrosis in 2 (3.1%) cases, graft oedema in 3 (4.6%) cases and graft displacement in 3 (4.6%) cases. CONCLUSION: The intraoperative application of 0.02% MMC with CAG markedly reduces the risk of re-recurrence of pterygium and postoperative complications. SN - 1681-7168 UR - https://www.unboundmedicine.com/medline/citation/23458043/Outcome_of_recurrent_pterygium_with_intraoperative_0_02_mitomycin_C_and_free_flap_limbal_conjunctival_autograft_ DB - PRIME DP - Unbound Medicine ER -